Reviewed, UniProtKB/Swiss-Prot P04375 (CU38_LOCMI)

Names and origin

Protein names	Recommended name:     Cuticle protein 38 Alternative name(s):     LM-ACP 38       Short name=LM-38
Organism	Locusta migratoria (Migratory locust)
Taxonomic identifier	7004 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Orthopteroidea › Orthoptera › Caelifera › Acridomorpha › Acridoidea › Acrididae › Oedipodinae › Locusta

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	structural constituent of cuticle Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 163	163	Cuticle protein 38		PRO_0000196105
Regions
	Repeat	7 – 10	4	1
	Repeat	13 – 16	4	2
	Repeat	20 – 23	4	3
	Repeat	26 – 29	4	4
	Repeat	56 – 59	4	5
	Repeat	62 – 65	4	6
	Repeat	68 – 71	4	7
	Repeat	75 – 78	4	8
	Repeat	81 – 84	4	9
	Repeat	93 – 96	4	10
	Repeat	123 – 126	4	11
	Repeat	135 – 138	4	12
	Repeat	141 – 144	4	13
	Repeat	156 – 159	4	14

Sequences

	Sequence		Length	Mass (Da)
	P04375-1 [UniParc]. Last modified March 20, 1987. Version 1. Checksum: FBB8C99E2CA66F49	FASTA	163	15,321
	10 20 30 40 50 60 GYLGGIAAPV GYAAPAVGYA APAIAAAPVA VAHAVAPAAA SVANTYRISQ TARVLAAPAA 70 80 90 100 110 120 YAAPAVAAAP AIGYAAPAIA AAPALGYARY AAAAPVAVAH AAVPAAASVA NTYRISQTAR 130 140 150 160 LLAAPAVAHA PVAYAAPAAY AAPAIGYGYG GLAYGAAPVA KVY

References

[1]	"Primary structure of a structural protein from the cuticle of the migratory locust, Locusta migratoria." Hoejrup P., Andersen S.O., Roepstorff P. Biochem. J. 236:713-720(1986) [PubMed: 3790088] [Abstract] Cited for: PROTEIN SEQUENCE.
[2]	"Isolation, characterization, and N-terminal sequence studies of cuticular proteins from the migratory locust, Locusta migratoria." Hoejrup P., Andersen S.O., Roepstorff P. Eur. J. Biochem. 154:153-159(1986) [PubMed: 3943519] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-30.

Cross-references

Sequence databases
PIR	UCLQ38. A03327.
3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CU38_LOCMI

Accession

Primary (citable) accession number: P04375

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 1987
Last sequence update:	March 20, 1987
Last modified:	May 5, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)