P04249 (MYG_PROGU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Myoglobin

Gene names

Name:

MB

Organism

Proechimys guairae (Guaira spiny rat)

Taxonomic identifier

10163 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Hystricognathi › Echimyidae › Proechimys

Protein attributes

Sequence length	154 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Sequence similarities	Belongs to the globin family.

Ontologies

Keywords
Biological process	Oxygen transport Transport
Ligand	Heme Iron Metal-binding
Molecular function	Muscle protein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro oxygen binding Inferred from electronic annotation. Source: InterPro oxygen transporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.1
	Chain	2 – 154	153	Myoglobin		PRO_0000053339
Sites
	Metal binding	65	1	Iron (heme distal ligand)
	Metal binding	94	1	Iron (heme proximal ligand)

Sequences

	Sequence		Length	Mass (Da)
	P04249 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 71F74308FA1A4503	FASTA	154	16,999
	10 20 30 40 50 60 MGLSDGEWQL VLNVWGKVEG DLSGHGQEVL IRLFKGHPET LEKFDKFKHL KAEDEMRASE 70 80 90 100 110 120 ELKKHGTTVL TALGGILKKK GQHAAELAPL AQSHATKHKI PVKYLEFISE AIIQVLQSKH 130 140 150 PGDFGADAQG AMSKALELFR NDIAAKYKEL GFQG

References

[1]	"The myoglobin of rodents Proechimys guairae (casiragua) and Mus musculus (house mouse)." Harris D.E., Gurnett A.M., Lehmann H., Joysey K.A. FEBS Lett. 190:288-292(1985) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-154.

Cross-references

Sequence databases
PIR	MYKS. A02486.
3D structure databases
ProteinModelPortal	P04249.
SMR	P04249. Positions 2-154.
ModBase	Search...
Proteomic databases
PRIDE	P04249.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG107340.
Family and domain databases
Gene3D	1.10.490.10. 1 hit.
InterPro	IPR000971. Globin. IPR009050. Globin-like. IPR012292. Globin_dom. IPR002335. Myoglobin. [Graphical view]
PANTHER	PTHR11442:SF5. PTHR11442:SF5. 1 hit.
Pfam	PF00042. Globin. 1 hit. [Graphical view]
PRINTS	PR00613. MYOGLOBIN.
SUPFAM	SSF46458. Globin_like. 1 hit.
PROSITE	PS01033. GLOBIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MYG_PROGU

Accession

Primary (citable) accession number: P04249

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 1987
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 62 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program