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P04247 (MYG_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 114. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Myoglobin
Gene names
Name:Mb
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length154 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sequence similarities

Belongs to the globin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.3
Chain2 – 154153Myoglobin
PRO_0000053319

Sites

Metal binding651Iron (heme distal ligand)
Metal binding941Iron (heme proximal ligand)

Experimental info

Sequence conflict1161L → K AA sequence Ref.3

Sequences

Sequence LengthMass (Da)Tools
P04247 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 8EE1EE3FFEE36AF0

FASTA15417,070
        10         20         30         40         50         60 
MGLSDGEWQL VLNVWGKVEA DLAGHGQEVL IGLFKTHPET LDKFDKFKNL KSEEDMKGSE 

        70         80         90        100        110        120 
DLKKHGCTVL TALGTILKKK GQHAAEIQPL AQSHATKHKI PVKYLEFISE IIIEVLKKRH 

       130        140        150 
SGDFGADAQG AMSKALELFR NDIAAKYKEL GFQG 

« Hide

References

« Hide 'large scale' references
[1]"The mouse myoglobin gene. Characterisation and sequence comparison with other mammalian myoglobin genes."
Blanchetot A., Price M., Jeffreys A.J.
Eur. J. Biochem. 159:469-474(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Mammary gland.
[3]"The myoglobin of rodents Proechimys guairae (casiragua) and Mus musculus (house mouse)."
Harris D.E., Gurnett A.M., Lehmann H., Joysey K.A.
FEBS Lett. 190:288-292(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-154.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC025172 mRNA. Translation: AAH25172.1.
X04405, X04417 Genomic DNA. Translation: CAA27994.1.
PIRMYMS. A25799.
RefSeqNP_001157519.1. NM_001164047.1.
NP_001157520.1. NM_001164048.1.
NP_038621.2. NM_013593.3.
UniGeneMm.404074.

3D structure databases

ProteinModelPortalP04247.
SMRP04247. Positions 2-154.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP04247. 2 interactions.
MINTMINT-4102659.
STRING10090.ENSMUSP00000019037.

PTM databases

PhosphoSiteP04247.

2D gel databases

SWISS-2DPAGEP04247.

Proteomic databases

PaxDbP04247.
PRIDEP04247.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000019037; ENSMUSP00000019037; ENSMUSG00000018893.
ENSMUST00000166179; ENSMUSP00000128399; ENSMUSG00000018893.
ENSMUST00000169226; ENSMUSP00000125995; ENSMUSG00000018893.
GeneID17189.
KEGGmmu:17189.
UCSCuc007wmx.2. mouse.

Organism-specific databases

CTD4151.
MGIMGI:96922. Mb.

Phylogenomic databases

eggNOGNOG276460.
HOGENOMHOG000070111.
HOVERGENHBG107340.
InParanoidP04247.
OMATKHKIPI.
OrthoDBEOG7KSX9V.
PhylomeDBP04247.
TreeFamTF332967.

Gene expression databases

ArrayExpressP04247.
BgeeP04247.
CleanExMM_MB.
GenevestigatorP04247.

Family and domain databases

Gene3D1.10.490.10. 1 hit.
InterProIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
IPR002335. Myoglobin.
[Graphical view]
PANTHERPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamPF00042. Globin. 1 hit.
[Graphical view]
PRINTSPR00613. MYOGLOBIN.
SUPFAMSSF46458. SSF46458. 1 hit.
PROSITEPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio291526.
PROP04247.
SOURCESearch...

Entry information

Entry nameMYG_MOUSE
AccessionPrimary (citable) accession number: P04247
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 1987
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 114 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot