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P04164

- CY552_THETH

UniProt

P04164 - CY552_THETH

Protein

Cytochrome c-552

Gene

cycA

Organism
Thermus thermophilus
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    This monoheme basic protein appears to function as an electron donor to cytochrome oxidase in T.thermophilus.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei11 – 111Heme (covalent)
    Binding sitei14 – 141Heme (covalent)
    Metal bindingi15 – 151Iron (heme axial ligand)
    Metal bindingi69 – 691Iron (heme axial ligand)

    GO - Molecular functioni

    1. electron carrier activity Source: InterPro
    2. heme binding Source: InterPro
    3. iron ion binding Source: InterPro

    GO - Biological processi

    1. oxidation-reduction process Source: UniProtKB-KW

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c-552
    Alternative name(s):
    Cytochrome c552
    Gene namesi
    Name:cycA
    OrganismiThermus thermophilus
    Taxonomic identifieri274 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 131›131Cytochrome c-552PRO_0000108402Add
    BLAST

    Post-translational modificationi

    Binds 1 heme group per subunit.

    Interactioni

    Protein-protein interaction databases

    STRINGi262724.TTC1058.

    Structurei

    Secondary structure

    1
    131
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi4 – 74
    Helixi9 – 157
    Turni16 – 183
    Turni23 – 253
    Helixi32 – 376
    Helixi42 – 5211
    Beta strandi54 – 607
    Beta strandi63 – 697
    Helixi77 – 8913
    Helixi94 – 963
    Beta strandi97 – 993
    Helixi105 – 1117
    Helixi118 – 1269

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1C52X-ray1.28A1-131[»]
    1QYZX-ray1.40A1-131[»]
    1R0QX-ray1.61A1-131[»]
    2FWLNMR-A1-131[»]
    3VNWX-ray1.97A3-131[»]
    ProteinModelPortaliP04164.
    SMRiP04164. Positions 1-131.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP04164.

    Family & Domainsi

    Family and domain databases

    Gene3Di1.10.760.10. 1 hit.
    InterProiIPR009056. Cyt_c-like_dom.
    IPR003088. Cyt_c_dom.
    [Graphical view]
    PfamiPF00034. Cytochrom_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF46626. SSF46626. 1 hit.
    PROSITEiPS51007. CYTC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P04164-1 [UniParc]FASTAAdd to Basket

    « Hide

    QADGAKIYAQ CAGCHQQNGQ GIPGAFPPLA GHVAEILAKE GGREYLILVL    50
    LYGLQGQIEV KGMKYNGVMS SFAQLKDEEI AAVLNHIATA WGDAKKVKGF 100
    KPFTAEEVKK LRAKKLTPQQ VLAERKKLGL K 131
    Length:131
    Mass (Da):14,173
    Last modified:May 24, 2005 - v3
    Checksum:i2E7E405D8A89C3BF
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    PIRiA00112. CCTW5T.

    Cross-referencesi

    Sequence databases

    PIRi A00112. CCTW5T.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1C52 X-ray 1.28 A 1-131 [» ]
    1QYZ X-ray 1.40 A 1-131 [» ]
    1R0Q X-ray 1.61 A 1-131 [» ]
    2FWL NMR - A 1-131 [» ]
    3VNW X-ray 1.97 A 3-131 [» ]
    ProteinModelPortali P04164.
    SMRi P04164. Positions 1-131.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262724.TTC1058.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei P04164.

    Family and domain databases

    Gene3Di 1.10.760.10. 1 hit.
    InterProi IPR009056. Cyt_c-like_dom.
    IPR003088. Cyt_c_dom.
    [Graphical view ]
    Pfami PF00034. Cytochrom_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46626. SSF46626. 1 hit.
    PROSITEi PS51007. CYTC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Thermus thermophilus cytochrome-c552: a new highly thermostable cytochrome-c structure obtained by MAD phasing."
      Than M.E., Hof P., Huber R., Bourenkov G.P., Bartunik H.D., Buse G., Soulimane T.
      J. Mol. Biol. 271:629-644(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.28 ANGSTROMS).

    Entry informationi

    Entry nameiCY552_THETH
    AccessioniPrimary (citable) accession number: P04164
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 20, 1987
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 95 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    The sequence shown here has been extracted from PDB entry 1C52.Curated

    Keywords - Technical termi

    3D-structure

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3