P04164 (CY552_THETH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c-552

Alternative name(s):
Cytochrome c552

Gene names

Name:

cycA

Organism

Thermus thermophilus

Taxonomic identifier

274 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	131 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This monoheme basic protein appears to function as an electron donor to cytochrome oxidase in T.thermophilus.
Post-translational modification	Binds 1 heme group per subunit.
Caution	The sequence shown here has been extracted from PDB entry 1C52.

Ontologies

Keywords
Biological process	Electron transport Transport
Ligand	Heme Iron Metal-binding
Technical term	3D-structure
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

‹1 – 131

›131

Cytochrome c-552

PRO_0000108402

Sites

Metal binding

15

1

Iron (heme axial ligand)

Metal binding

69

1

Iron (heme axial ligand)

Binding site

11

1

Heme (covalent)

Binding site

14

1

Heme (covalent)

Experimental info

Non-terminal residue

1

1

Secondary structure

1

.

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131

Helix Strand Turn

Details...

Helix

4 – 7

4

Helix

9 – 15

7

Turn

16 – 18

3

Turn

23 – 25

3

Helix

32 – 37

6

Helix

42 – 52

11

Beta strand

54 – 60

7

Beta strand

63 – 69

7

Helix

77 – 89

13

Helix

94 – 96

3

Beta strand

97 – 99

3

Helix

105 – 111

7

Helix

118 – 126

9

Sequences

	Sequence		Length	Mass (Da)
	P04164 [UniParc]. Last modified May 24, 2005. Version 3. Checksum: 2E7E405D8A89C3BF	FASTA	131	14,173
	10 20 30 40 50 60 QADGAKIYAQ CAGCHQQNGQ GIPGAFPPLA GHVAEILAKE GGREYLILVL LYGLQGQIEV 70 80 90 100 110 120 KGMKYNGVMS SFAQLKDEEI AAVLNHIATA WGDAKKVKGF KPFTAEEVKK LRAKKLTPQQ 130 VLAERKKLGL K

References

[1]	"Thermus thermophilus cytochrome-c552: a new highly thermostable cytochrome-c structure obtained by MAD phasing." Than M.E., Hof P., Huber R., Bourenkov G.P., Bartunik H.D., Buse G., Soulimane T. J. Mol. Biol. 271:629-644(1997) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.28 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

PIR

CCTW5T. A00112.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1C52	X-ray	1.28	A	1-131	[»]
1QYZ	X-ray	1.40	A	1-131	[»]
1R0Q	X-ray	1.61	A	1-131	[»]
2FWL	NMR	-	A	1-131	[»]
3VNW	X-ray	1.97	A	3-131	[»]

ProteinModelPortal

P04164.

SMR

P04164. Positions 1-131.

ModBase

Search...

Protein-protein interaction databases

STRING

262724.TTC1058.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR009056. Cyt_c_dom.
IPR003088. Cyt_c_I.
[Graphical view]

Pfam

PF00034. Cytochrom_C. 1 hit.
[Graphical view]

SUPFAM

SSF46626. Cytochrome_c. 1 hit.

PROSITE

PS51007. CYTC. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

P04164.

Entry information

Entry name

CY552_THETH

Accession

Primary (citable) accession number: P04164

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 1987
Last sequence update:	May 24, 2005
Last modified:	April 3, 2013
This is version 91 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program