##gff-version 3
P04155	UniProtKB	Signal peptide	1	24	.	.	.	Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15340161,ECO:0000269|PubMed:15924415,ECO:0000269|PubMed:16308573,ECO:0000269|PubMed:3146413,ECO:0000269|PubMed:3261981;Dbxref=PMID:15340161,PMID:15924415,PMID:16308573,PMID:3146413,PMID:3261981	
P04155	UniProtKB	Chain	25	84	.	.	.	ID=PRO_0000023456;Note=Trefoil factor 1	
P04155	UniProtKB	Domain	29	72	.	.	.	Note=P-type;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00779	
P04155	UniProtKB	Disulfide bond	31	57	.	.	.	.	
P04155	UniProtKB	Disulfide bond	41	56	.	.	.	.	
P04155	UniProtKB	Disulfide bond	51	68	.	.	.	.	
P04155	UniProtKB	Natural variant	22	22	.	.	.	ID=VAR_053563;Note=T->I;Dbxref=dbSNP:rs34795821	
P04155	UniProtKB	Natural variant	32	32	.	.	.	ID=VAR_015281;Note=In a gastric carcinoma sample%3B somatic mutation. T->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10982763;Dbxref=PMID:10982763	
P04155	UniProtKB	Natural variant	32	32	.	.	.	ID=VAR_015282;Note=In a gastric carcinoma sample%3B somatic mutation. T->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10982763;Dbxref=PMID:10982763	
P04155	UniProtKB	Natural variant	34	34	.	.	.	ID=VAR_015283;Note=In a gastric carcinoma sample%3B somatic mutation%3B abolishes inhibition of gastric cancer cell growth%3B abolishes inhibition of apoptosis in gasterointestinal epithelial cells%3B increases invasive activity in epithelial cells. A->D;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10982763,ECO:0000269|PubMed:16697734;Dbxref=dbSNP:rs961505229,PMID:10982763,PMID:16697734	
P04155	UniProtKB	Natural variant	37	37	.	.	.	ID=VAR_015284;Note=In a gastric carcinoma sample%3B somatic mutation%3B abolishes inhibition of gastric cancer cell growth%3B abolishes inhibition of apoptosis in gasterointestinal epithelial cells%3B increases invasive activity in epithelial cells. E->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10982763,ECO:0000269|PubMed:16697734;Dbxref=PMID:10982763,PMID:16697734	
P04155	UniProtKB	Natural variant	46	46	.	.	.	ID=VAR_015285;Note=In a gastric adenoma sample%3B somatic mutation. V->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10982763;Dbxref=PMID:10982763	
P04155	UniProtKB	Natural variant	55	55	.	.	.	ID=VAR_015286;Note=In a gastric carcinoma sample%3B somatic mutation. G->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10982763;Dbxref=dbSNP:rs1203145163,PMID:10982763	
P04155	UniProtKB	Mutagenesis	82	82	.	.	.	Note=Abolishes inhibition of gastric cancer cell growth. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16697734;Dbxref=PMID:16697734	
P04155	UniProtKB	Beta strand	29	31	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6V1D	
P04155	UniProtKB	Helix	35	37	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6V1D	
P04155	UniProtKB	Beta strand	40	42	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1HI7	
P04155	UniProtKB	Helix	48	53	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6V1D	
P04155	UniProtKB	Beta strand	61	65	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1HI7	
P04155	UniProtKB	Beta strand	67	69	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6V1D	
P04155	UniProtKB	Beta strand	72	74	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1HI7	
P04155	UniProtKB	Beta strand	79	82	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1HI7