P04140 (MERT_PSEAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mercuric transport protein

Alternative name(s):
Mercury ion transport protein

Gene names

Name:

merT

Encoded on

Plasmid pVS1

Organism

Pseudomonas aeruginosa

Taxonomic identifier

287 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa group

Protein attributes

Sequence length	116 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function	Involved in mercuric transport. Passes a mercury ion from the periplasmic MerP protein to the mercuric reductase (MerA).
Subcellular location	Cell inner membrane; Multi-pass membrane protein.

Ontologies

Keywords
Biological process	Mercuric resistance Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	Mercury Metal-binding
Technical term	Plasmid Transposable element
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	mercury ion transmembrane transporter activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 116	116	Mercuric transport protein		PRO_0000096430
Regions
	Transmembrane	16 – 36	21	Helical; Potential
	Transmembrane	44 – 64	21	Helical; Potential
	Transmembrane	94 – 114	21	Helical; Potential
Sites
	Metal binding	24	1	Mercury Potential
	Metal binding	25	1	Mercury Potential
	Metal binding	76	1	Mercury Potential
	Metal binding	82	1	Mercury Potential

Sequences

	Sequence		Length	Mass (Da)
	P04140 [UniParc]. Last modified November 1, 1986. Version 1. Checksum: 905B5492AFE08E6C	FASTA	116	12,498
	10 20 30 40 50 60 MSEPKTGRGA LFTGGLAAIL ASACCLGPLV LIALGFSGAW IGNLAVLEPY RPIFIGVALV 70 80 90 100 110 ALFFAWRRIY RQAAACKPGE VCAIPQVRAT YKLIFWIVAA LVLVALGFPY VMPFFY

References

[1]

"Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes." Misra T.K., Brown N.L., Fritzinger D.C., Pridmore R.D., Barnes W.M., Haberstroh L., Silver S. Proc. Natl. Acad. Sci. U.S.A. 81:5975-5979(1984) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Transposon: Tn501.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z00027 Genomic DNA. Translation: CAA77321.1. K02503 Genomic DNA. Translation: AAA27433.1.
PIR	QQPSHT. A04457.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR003457. Transprt_MerT. [Graphical view]
Pfam	PF02411. MerT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MERT_PSEAI

Accession

Primary (citable) accession number: P04140

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1986
Last sequence update:	November 1, 1986
Last modified:	April 3, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program