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Protein

Glutamine synthetase cytosolic isozyme

Gene
N/A
Organism
Medicago sativa (Alfalfa)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

Irreversibly inhibited by the herbicide L-phosphinothricin (PPT).

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processNitrogen fixation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase cytosolic isozyme (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase
OrganismiMedicago sativa (Alfalfa)
Taxonomic identifieri3879 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeTrifolieaeMedicago

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001531831 – 356Glutamine synthetase cytosolic isozymeAdd BLAST356

Proteomic databases

PRIDEiP04078

Interactioni

Subunit structurei

Homooctamer.

Structurei

3D structure databases

ProteinModelPortaliP04078
SMRiP04078
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Family and domain databases

Gene3Di3.10.20.70, 1 hit
InterProiView protein in InterPro
IPR008147 Gln_synt_b-grasp
IPR036651 Gln_synt_N
IPR014746 Gln_synth/guanido_kin_cat_dom
IPR008146 Gln_synth_cat_dom
IPR027303 Gln_synth_gly_rich_site
IPR027302 Gln_synth_N_conserv_site
PfamiView protein in Pfam
PF00120 Gln-synt_C, 1 hit
PF03951 Gln-synt_N, 1 hit
SMARTiView protein in SMART
SM01230 Gln-synt_C, 1 hit
SUPFAMiSSF54368 SSF54368, 1 hit
SSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00180 GLNA_1, 1 hit
PS00181 GLNA_ATP, 1 hit

Sequencei

Sequence statusi: Complete.

P04078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLLSDLINL DLSETTEKII AEYIWIGGSG LDLRSKARTL PGPVTDPSQL
60 70 80 90 100
PKWNYDGSST GQAPGEDSEV IIYPQAIFKD PFRRGNNILV MCDAYTPAGE
110 120 130 140 150
PIPTNKRHAA AKIFSHPDVV AEVPWYGIEQ EYTLLQKDIN WPLGWPVGGF
160 170 180 190 200
PGPQGPYYCG AGADKAFGRD IVDSHYKACL YAGINISGIN GEVMPGQWEF
210 220 230 240 250
QVGPSVGISA GDEIWVARYI LERITEVAGV VLSFDPKPIK GDWNGAGAHT
260 270 280 290 300
NYSTKSMRED GGYEVILKAI EKLGKKHKEH IAAYGEGNER RLTGRHETAD
310 320 330 340 350
INTFLWGVAN RGASIRVGRD TEKAGKGYFE DRRPSSNMDP YVVTSMIADT

TILWKP
Length:356
Mass (Da):39,107
Last modified:November 1, 1986 - v1
Checksum:iB4450F5489B27BD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K03282 mRNA Translation: AAA32654.1
X03931 Genomic DNA Translation: CAA27570.1
PIRiA26025 AJAAQ

Similar proteinsi

Entry informationi

Entry nameiGLNA1_MEDSA
AccessioniPrimary (citable) accession number: P04078
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1986
Last sequence update: November 1, 1986
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health