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P04078

- GLNA1_MEDSA

UniProt

P04078 - GLNA1_MEDSA

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Protein

Glutamine synthetase cytosolic isozyme

Gene
N/A
Organism
Medicago sativa (Alfalfa)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
  2. nitrogen fixation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Nitrogen fixation

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase cytosolic isozyme (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase
OrganismiMedicago sativa (Alfalfa)
Taxonomic identifieri3879 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeTrifolieaeMedicago

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 356356Glutamine synthetase cytosolic isozymePRO_0000153183Add
BLAST

Proteomic databases

ProMEXiP04078.

Interactioni

Subunit structurei

Homooctamer.

Structurei

3D structure databases

ProteinModelPortaliP04078.
SMRiP04078. Positions 4-355.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P04078-1 [UniParc]FASTAAdd to Basket

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MSLLSDLINL DLSETTEKII AEYIWIGGSG LDLRSKARTL PGPVTDPSQL    50
PKWNYDGSST GQAPGEDSEV IIYPQAIFKD PFRRGNNILV MCDAYTPAGE 100
PIPTNKRHAA AKIFSHPDVV AEVPWYGIEQ EYTLLQKDIN WPLGWPVGGF 150
PGPQGPYYCG AGADKAFGRD IVDSHYKACL YAGINISGIN GEVMPGQWEF 200
QVGPSVGISA GDEIWVARYI LERITEVAGV VLSFDPKPIK GDWNGAGAHT 250
NYSTKSMRED GGYEVILKAI EKLGKKHKEH IAAYGEGNER RLTGRHETAD 300
INTFLWGVAN RGASIRVGRD TEKAGKGYFE DRRPSSNMDP YVVTSMIADT 350
TILWKP 356
Length:356
Mass (Da):39,107
Last modified:November 1, 1986 - v1
Checksum:iB4450F5489B27BD7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
K03282 mRNA. Translation: AAA32654.1.
X03931 Genomic DNA. Translation: CAA27570.1.
PIRiA26025. AJAAQ.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
K03282 mRNA. Translation: AAA32654.1 .
X03931 Genomic DNA. Translation: CAA27570.1 .
PIRi A26025. AJAAQ.

3D structure databases

ProteinModelPortali P04078.
SMRi P04078. Positions 4-355.
ModBasei Search...
MobiDBi Search...

Proteomic databases

ProMEXi P04078.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence of an alfalfa glutamine synthetase gene."
    Tischer E., Dassarma S., Goodman H.M.
    Mol. Gen. Genet. 203:221-229(1986)
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Herbicide-resistant alfalfa cells: an example of gene amplification in plants."
    Donn G., Tischer E., Smith J.A., Goodman H.M.
    J. Mol. Appl. Genet. 2:621-635(1984) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 266-356.

Entry informationi

Entry nameiGLNA1_MEDSA
AccessioniPrimary (citable) accession number: P04078
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1986
Last sequence update: November 1, 1986
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Irreversibly inhibited by the herbicide L-phosphinothricin (PPT).

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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