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P03975 (IGEB_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
IgE-binding protein
Gene names
Name:Iap
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length557 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Miscellaneous

This hybridoma was generated by fusion of rat lymphocytes with cells of the AKR mouse thyoma BW5147.

This sequence binds only rat IgE.

Sequence similarities

Contains 1 integrase catalytic domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 557557IgE-binding protein
PRO_0000084173

Regions

Domain344 – 534191Integrase catalytic

Sequences

Sequence LengthMass (Da)Tools
P03975 [UniParc].

Last modified October 23, 1986. Version 1.
Checksum: C53C479890B7FD82

FASTA55762,747
        10         20         30         40         50         60 
MALQVMFGLE FFLVLEALLF LFTCYQVVKA GRILDEIQDK LSEVKRGERV GTKRKYGTQN 

        70         80         90        100        110        120 
KYTGLSKGLE PEEKLRLGRN TWREIRRKRG KREKKKDQLA EVSRKRSLCS SLDGLGKPAL 

       130        140        150        160        170        180 
SSSEAGEESS SEETDWEEEA AHYQPANWSR KKPKAAGEGQ FADWPQGSRL QGPPYAESPP 

       190        200        210        220        230        240 
CVVRQQCAER CAERQCAERQ CADSFIPREE QRKIQQAFPV FEGAEGGRVH APVEYLQIKE 

       250        260        270        280        290        300 
IAESVRKYGT NANFTLVQLD RLAGMALTPA DWQTVVKAAL PSMGKYMEWR ALWHEAAQAQ 

       310        320        330        340        350        360 
ARANAAALTP EQRDWTFDLL TGQGAYSADQ TNYHWGAYAQ ISSTAIRPGR RSRAGETTGQ 

       370        380        390        400        410        420 
LTKIIQGPQE SFSDFVARMT EAAERIFGES EQAAPLIEQL IYEQATKECR AVHSPKKEQR 

       430        440        450        460        470        480 
LTRLAQGLSR AWGKPRLLKT DNGPAYTSQK FQQFCRQMDV THLTGLPYNP QGQGIVERAH 

       490        500        510        520        530        540 
RTLKAYLIKQ KRGTFEETVP RAPRVSVSLA LFTLNFLNID AHGHTAAERH VQSQIGPMRW 

       550 
LNGKMSLIIN GMARILS 

« Hide

References

[1]"cDNA clones encoding IgE-binding factors from a rat-mouse T-cell hybridoma."
Martens C.L., Huff T.F., Jardieu P., Trounstine M.L., Coffman R.L., Ishizaka K., Moore K.W.
Proc. Natl. Acad. Sci. U.S.A. 82:2460-2464(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M10062 mRNA. Translation: AAA37291.1.
PIREBRTMS. A01858.

3D structure databases

ProteinModelPortalP03975.
SMRP03975. Positions 219-419, 433-534.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP03975.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:96306. Iap.

Gene expression databases

GenevestigatorP03975.

Family and domain databases

Gene3D1.10.1200.30. 1 hit.
1.10.375.10. 1 hit.
3.30.420.10. 1 hit.
InterProIPR000721. Gag_p24.
IPR001584. Integrase_cat-core.
IPR008916. Retrov_capsid_C.
IPR008919. Retrov_capsid_N.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamPF00607. Gag_p24. 1 hit.
PF00665. rve. 1 hit.
[Graphical view]
SUPFAMSSF47353. SSF47353. 1 hit.
SSF47943. SSF47943. 1 hit.
SSF53098. SSF53098. 1 hit.
PROSITEPS50994. INTEGRASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameIGEB_MOUSE
AccessionPrimary (citable) accession number: P03975
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 1986
Last sequence update: October 23, 1986
Last modified: April 16, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot