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Protein

IgE-binding protein

Gene

Iap

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro

GO - Biological processi

  1. DNA integration Source: InterPro
  2. viral process Source: InterPro
Complete GO annotation...

Keywords - Ligandi

IgE-binding protein

Names & Taxonomyi

Protein namesi
Recommended name:
IgE-binding protein
Gene namesi
Name:Iap
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:96306. Iap.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 557557IgE-binding proteinPRO_0000084173Add
BLAST

Proteomic databases

MaxQBiP03975.
PRIDEiP03975.

Expressioni

Gene expression databases

GenevestigatoriP03975.

Structurei

3D structure databases

ProteinModelPortaliP03975.
SMRiP03975. Positions 219-351, 433-534.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini344 – 534191Integrase catalyticPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 integrase catalytic domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.1200.30. 1 hit.
1.10.375.10. 1 hit.
3.30.420.10. 1 hit.
InterProiIPR000721. Gag_p24.
IPR001584. Integrase_cat-core.
IPR008916. Retrov_capsid_C.
IPR008919. Retrov_capsid_N.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00607. Gag_p24. 1 hit.
PF00665. rve. 1 hit.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF47943. SSF47943. 1 hit.
SSF53098. SSF53098. 1 hit.
PROSITEiPS50994. INTEGRASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P03975-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALQVMFGLE FFLVLEALLF LFTCYQVVKA GRILDEIQDK LSEVKRGERV
60 70 80 90 100
GTKRKYGTQN KYTGLSKGLE PEEKLRLGRN TWREIRRKRG KREKKKDQLA
110 120 130 140 150
EVSRKRSLCS SLDGLGKPAL SSSEAGEESS SEETDWEEEA AHYQPANWSR
160 170 180 190 200
KKPKAAGEGQ FADWPQGSRL QGPPYAESPP CVVRQQCAER CAERQCAERQ
210 220 230 240 250
CADSFIPREE QRKIQQAFPV FEGAEGGRVH APVEYLQIKE IAESVRKYGT
260 270 280 290 300
NANFTLVQLD RLAGMALTPA DWQTVVKAAL PSMGKYMEWR ALWHEAAQAQ
310 320 330 340 350
ARANAAALTP EQRDWTFDLL TGQGAYSADQ TNYHWGAYAQ ISSTAIRPGR
360 370 380 390 400
RSRAGETTGQ LTKIIQGPQE SFSDFVARMT EAAERIFGES EQAAPLIEQL
410 420 430 440 450
IYEQATKECR AVHSPKKEQR LTRLAQGLSR AWGKPRLLKT DNGPAYTSQK
460 470 480 490 500
FQQFCRQMDV THLTGLPYNP QGQGIVERAH RTLKAYLIKQ KRGTFEETVP
510 520 530 540 550
RAPRVSVSLA LFTLNFLNID AHGHTAAERH VQSQIGPMRW LNGKMSLIIN

GMARILS
Length:557
Mass (Da):62,747
Last modified:October 23, 1986 - v1
Checksum:iC53C479890B7FD82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M10062 mRNA. Translation: AAA37291.1.
PIRiA01858. EBRTMS.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M10062 mRNA. Translation: AAA37291.1.
PIRiA01858. EBRTMS.

3D structure databases

ProteinModelPortaliP03975.
SMRiP03975. Positions 219-351, 433-534.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiP03975.
PRIDEiP03975.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:96306. Iap.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

GenevestigatoriP03975.

Family and domain databases

Gene3Di1.10.1200.30. 1 hit.
1.10.375.10. 1 hit.
3.30.420.10. 1 hit.
InterProiIPR000721. Gag_p24.
IPR001584. Integrase_cat-core.
IPR008916. Retrov_capsid_C.
IPR008919. Retrov_capsid_N.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00607. Gag_p24. 1 hit.
PF00665. rve. 1 hit.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF47943. SSF47943. 1 hit.
SSF53098. SSF53098. 1 hit.
PROSITEiPS50994. INTEGRASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiIGEB_MOUSE
AccessioniPrimary (citable) accession number: P03975
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 1986
Last sequence update: October 23, 1986
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This hybridoma was generated by fusion of rat lymphocytes with cells of the AKR mouse thyoma BW5147.
This sequence binds only rat IgE.

Keywords - Technical termi

Complete proteome, Hybridoma, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.