Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P03897

- NU3M_HUMAN

UniProt

P03897 - NU3M_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

NADH-ubiquinone oxidoreductase chain 3

Gene

MT-ND3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).

GO - Molecular functioni

  1. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB

GO - Biological processi

  1. cellular metabolic process Source: Reactome
  2. mitochondrial electron transport, NADH to ubiquinone Source: UniProtKB
  3. respiratory electron transport chain Source: Reactome
  4. small molecule metabolic process Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Enzyme and pathway databases

ReactomeiREACT_22393. Respiratory electron transport.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase chain 3 (EC:1.6.5.3)
Alternative name(s):
NADH dehydrogenase subunit 3
Gene namesi
Name:MT-ND3
Synonyms:MTND3, NADH3, ND3
Encoded oniMitochondrion
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Mitochondrion

Organism-specific databases

HGNCiHGNC:7458. MT-ND3.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: Reactome
  3. mitochondrial respiratory chain complex I Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion

Pathology & Biotechi

Involvement in diseasei

Leigh syndrome (LS) [MIM:256000]: An early-onset progressive neurodegenerative disorder characterized by the presence of focal, bilateral lesions in one or more areas of the central nervous system including the brainstem, thalamus, basal ganglia, cerebellum and spinal cord. Clinical features depend on which areas of the central nervous system are involved and include subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, and dysphagia.1 Publication
Note: The disease is caused by mutations affecting the gene represented in this entry.
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti47 – 471A → T in LS and MT-C1D. 2 Publications
VAR_035092
Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.3 Publications
Note: The disease is caused by mutations affecting the gene represented in this entry.
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti34 – 341S → P in MT-C1D. 2 Publications
VAR_064564
Natural varianti45 – 451S → P in MT-C1D. 2 Publications
VAR_035091
Natural varianti47 – 471A → T in LS and MT-C1D. 2 Publications
VAR_035092

Keywords - Diseasei

Disease mutation, Leigh syndrome

Organism-specific databases

MIMi252010. phenotype.
256000. phenotype.
Orphaneti99718. Leber plus disease.
255210. Maternally-inherited Leigh syndrome.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 115115NADH-ubiquinone oxidoreductase chain 3PRO_0000117752Add
BLAST

Proteomic databases

MaxQBiP03897.
PaxDbiP03897.
PRIDEiP03897.

PTM databases

PhosphoSiteiP03897.

Expressioni

Gene expression databases

BgeeiP03897.
ExpressionAtlasiP03897. baseline.
GenevestigatoriP03897.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
APPP050672EBI-1246249,EBI-821758

Protein-protein interaction databases

IntActiP03897. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliP03897.
SMRiP03897. Positions 3-112.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalSequence AnalysisAdd
BLAST
Transmembranei55 – 7521HelicalSequence AnalysisAdd
BLAST
Transmembranei84 – 10421HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 3 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG282870.
HOVERGENiHBG017392.
InParanoidiP03897.
KOiK03880.
OMAiTTNLPLM.
OrthoDBiEOG7RV9K7.
PhylomeDBiP03897.
TreeFamiTF343336.

Family and domain databases

InterProiIPR000440. NADH_UbQ/plastoQ_OxRdtase_su3.
[Graphical view]
PANTHERiPTHR11058. PTHR11058. 1 hit.
PfamiPF00507. Oxidored_q4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P03897-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNFALILMIN TLLALLLMII TFWLPQLNGY MEKSTPYECG FDPMSPARVP
60 70 80 90 100
FSMKFFLVAI TFLLFDLEIA LLLPLPWALQ TTNLPLMVMS SLLLIIILAL
110
SLAYEWLQKG LDWTE
Length:115
Mass (Da):13,186
Last modified:July 21, 1986 - v1
Checksum:iFA9E0C13B5108EE6
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti10 – 101N → D.1 Publication
Corresponds to variant rs28358274 [ dbSNP | Ensembl ].
VAR_008391
Natural varianti34 – 341S → P in MT-C1D. 2 Publications
VAR_064564
Natural varianti45 – 451S → P in MT-C1D. 2 Publications
VAR_035091
Natural varianti47 – 471A → T in LS and MT-C1D. 2 Publications
VAR_035092
Natural varianti53 – 531M → V.1 Publication
VAR_008598
Natural varianti114 – 1141T → A.2 Publications
Corresponds to variant rs2853826 [ dbSNP | Ensembl ].
VAR_008392

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
J01415 Genomic DNA. Translation: AAB58950.1.
V00662 Genomic DNA. Translation: CAA24033.1.
AY339402 Genomic DNA. Translation: AAP89043.1.
AY339403 Genomic DNA. Translation: AAP89056.1.
AY339404 Genomic DNA. Translation: AAP89069.1.
AY339405 Genomic DNA. Translation: AAP89082.1.
AY339406 Genomic DNA. Translation: AAP89095.1.
AY339407 Genomic DNA. Translation: AAP89108.1.
AY339408 Genomic DNA. Translation: AAP89121.1.
AY339409 Genomic DNA. Translation: AAP89134.1.
AY339410 Genomic DNA. Translation: AAP89147.1.
AY339411 Genomic DNA. Translation: AAP89160.1.
AY339412 Genomic DNA. Translation: AAP89173.1.
AY339413 Genomic DNA. Translation: AAP89186.1.
AY339414 Genomic DNA. Translation: AAP89199.1.
AY339415 Genomic DNA. Translation: AAP89212.1.
AY339416 Genomic DNA. Translation: AAP89225.1.
AY339417 Genomic DNA. Translation: AAP89238.1.
AY339418 Genomic DNA. Translation: AAP89251.1.
AY339419 Genomic DNA. Translation: AAP89264.1.
AY339420 Genomic DNA. Translation: AAP89277.1.
AY339421 Genomic DNA. Translation: AAP89290.1.
AY339422 Genomic DNA. Translation: AAP89303.1.
AY339423 Genomic DNA. Translation: AAP89316.1.
AY339424 Genomic DNA. Translation: AAP89329.1.
AY339425 Genomic DNA. Translation: AAP89342.1.
AY339426 Genomic DNA. Translation: AAP89355.1.
AY339427 Genomic DNA. Translation: AAP89368.1.
AY339428 Genomic DNA. Translation: AAP89381.1.
AY339429 Genomic DNA. Translation: AAP89394.1.
AY339430 Genomic DNA. Translation: AAP89407.1.
AY339431 Genomic DNA. Translation: AAP89420.1.
AY339432 Genomic DNA. Translation: AAP89433.1.
AY339433 Genomic DNA. Translation: AAP89446.1.
AY339434 Genomic DNA. Translation: AAP89459.1.
AY339435 Genomic DNA. Translation: AAP89472.1.
AY339436 Genomic DNA. Translation: AAP89485.1.
AY339437 Genomic DNA. Translation: AAP89498.1.
AY339438 Genomic DNA. Translation: AAP89511.1.
AY339439 Genomic DNA. Translation: AAP89524.1.
AY339440 Genomic DNA. Translation: AAP89537.1.
AY339441 Genomic DNA. Translation: AAP89550.1.
AY339442 Genomic DNA. Translation: AAP89563.1.
AY339443 Genomic DNA. Translation: AAP89576.1.
AY339444 Genomic DNA. Translation: AAP89589.1.
AY339445 Genomic DNA. Translation: AAP89602.1.
AY339446 Genomic DNA. Translation: AAP89615.1.
AY339447 Genomic DNA. Translation: AAP89628.1.
AY339448 Genomic DNA. Translation: AAP89641.1.
AY339449 Genomic DNA. Translation: AAP89654.1.
AY339450 Genomic DNA. Translation: AAP89667.1.
AY339451 Genomic DNA. Translation: AAP89680.1.
AY339452 Genomic DNA. Translation: AAP89693.1.
AY339453 Genomic DNA. Translation: AAP89706.1.
AY339454 Genomic DNA. Translation: AAP89719.1.
AY339455 Genomic DNA. Translation: AAP89732.1.
AY339456 Genomic DNA. Translation: AAP89745.1.
AY339457 Genomic DNA. Translation: AAP89758.1.
AY339458 Genomic DNA. Translation: AAP89771.1.
AY339459 Genomic DNA. Translation: AAP89784.1.
AY339460 Genomic DNA. Translation: AAP89797.1.
AY339461 Genomic DNA. Translation: AAP89810.1.
AY339462 Genomic DNA. Translation: AAP89823.1.
AY339463 Genomic DNA. Translation: AAP89836.1.
AY339464 Genomic DNA. Translation: AAP89849.1.
AY339465 Genomic DNA. Translation: AAP89862.1.
AY339475 Genomic DNA. Translation: AAP89992.1.
AY339476 Genomic DNA. Translation: AAP90005.1.
AY339477 Genomic DNA. Translation: AAP90018.1.
AY339478 Genomic DNA. Translation: AAP90031.1.
AY339479 Genomic DNA. Translation: AAP90044.1.
AY339480 Genomic DNA. Translation: AAP90057.1.
AY339481 Genomic DNA. Translation: AAP90070.1.
AY339482 Genomic DNA. Translation: AAP90083.1.
AY339483 Genomic DNA. Translation: AAP90096.1.
AY339484 Genomic DNA. Translation: AAP90109.1.
AY339485 Genomic DNA. Translation: AAP90122.1.
AY339486 Genomic DNA. Translation: AAP90135.1.
AY339487 Genomic DNA. Translation: AAP90148.1.
AY339488 Genomic DNA. Translation: AAP90161.1.
AY339489 Genomic DNA. Translation: AAP90174.1.
AY339490 Genomic DNA. Translation: AAP90187.1.
AY339491 Genomic DNA. Translation: AAP90200.1.
AY339492 Genomic DNA. Translation: AAP90213.1.
AY339493 Genomic DNA. Translation: AAP90226.1.
AY339494 Genomic DNA. Translation: AAP90239.1.
AY339495 Genomic DNA. Translation: AAP90252.1.
AY339496 Genomic DNA. Translation: AAP90265.1.
AY339510 Genomic DNA. Translation: AAP90447.1.
AY339511 Genomic DNA. Translation: AAP90460.1.
AY339512 Genomic DNA. Translation: AAP90473.1.
AY339513 Genomic DNA. Translation: AAP90486.1.
AY339523 Genomic DNA. Translation: AAP90616.1.
AY339524 Genomic DNA. Translation: AAP90629.1.
AY339525 Genomic DNA. Translation: AAP90642.1.
AY339526 Genomic DNA. Translation: AAP90655.1.
AY339527 Genomic DNA. Translation: AAP90668.1.
AY339528 Genomic DNA. Translation: AAP90681.1.
AY339529 Genomic DNA. Translation: AAP90694.1.
AY339530 Genomic DNA. Translation: AAP90707.1.
AY339531 Genomic DNA. Translation: AAP90720.1.
AY339532 Genomic DNA. Translation: AAP90733.1.
AY339533 Genomic DNA. Translation: AAP90746.1.
AY339534 Genomic DNA. Translation: AAP90759.1.
AY339535 Genomic DNA. Translation: AAP90772.1.
AY339536 Genomic DNA. Translation: AAP90785.1.
AY339537 Genomic DNA. Translation: AAP90798.1.
AY339538 Genomic DNA. Translation: AAP90811.1.
AY339539 Genomic DNA. Translation: AAP90824.1.
AY339540 Genomic DNA. Translation: AAP90837.1.
AY339541 Genomic DNA. Translation: AAP90850.1.
AY339542 Genomic DNA. Translation: AAP90863.1.
AY339543 Genomic DNA. Translation: AAP90876.1.
AY339544 Genomic DNA. Translation: AAP90889.1.
AY339545 Genomic DNA. Translation: AAP90902.1.
AY339546 Genomic DNA. Translation: AAP90915.1.
AY339549 Genomic DNA. Translation: AAP90954.1.
AY339550 Genomic DNA. Translation: AAP90967.1.
AY339551 Genomic DNA. Translation: AAP90980.1.
AY339552 Genomic DNA. Translation: AAP90993.1.
AY339553 Genomic DNA. Translation: AAP91006.1.
AY339566 Genomic DNA. Translation: AAP91175.1.
AY339567 Genomic DNA. Translation: AAP91188.1.
AY339568 Genomic DNA. Translation: AAP91201.1.
AY339569 Genomic DNA. Translation: AAP91214.1.
AY339570 Genomic DNA. Translation: AAP91227.1.
AY339571 Genomic DNA. Translation: AAP91240.1.
AY339572 Genomic DNA. Translation: AAP91253.1.
AY339573 Genomic DNA. Translation: AAP91266.1.
AY339574 Genomic DNA. Translation: AAP91279.1.
AF346963 Genomic DNA. Translation: AAK17214.1.
AF346964 Genomic DNA. Translation: AAK17227.2.
AF346971 Genomic DNA. Translation: AAK17318.2.
AF346973 Genomic DNA. Translation: AAK17344.2.
AF346974 Genomic DNA. Translation: AAK17357.2.
AF346975 Genomic DNA. Translation: AAK17370.2.
AF346978 Genomic DNA. Translation: AAK17409.1.
AF346981 Genomic DNA. Translation: AAK17448.2.
AF346982 Genomic DNA. Translation: AAK17461.1.
AF346988 Genomic DNA. Translation: AAK17539.1.
AF346993 Genomic DNA. Translation: AAK17604.2.
AF347001 Genomic DNA. Translation: AAK17708.2.
AF347002 Genomic DNA. Translation: AAK17721.2.
AF347004 Genomic DNA. Translation: AAK17747.2.
AF347005 Genomic DNA. Translation: AAK17760.2.
AF347006 Genomic DNA. Translation: AAK17773.2.
AF347007 Genomic DNA. Translation: AAK17786.2.
AF347011 Genomic DNA. Translation: AAK17838.2.
AY289051 Genomic DNA. Translation: AAP47887.1.
AY289052 Genomic DNA. Translation: AAP47900.1.
AY289053 Genomic DNA. Translation: AAP47913.1.
AY289054 Genomic DNA. Translation: AAP47926.1.
AY289055 Genomic DNA. Translation: AAP47939.1.
AY289056 Genomic DNA. Translation: AAP47952.1.
AY289058 Genomic DNA. Translation: AAP47978.1.
AY289059 Genomic DNA. Translation: AAP47991.1.
AY289060 Genomic DNA. Translation: AAP48004.1.
AY289061 Genomic DNA. Translation: AAP48017.1.
AY289062 Genomic DNA. Translation: AAP48030.1.
AY289063 Genomic DNA. Translation: AAP48043.1.
AY289065 Genomic DNA. Translation: AAP48069.1.
AY289068 Genomic DNA. Translation: AAP48108.1.
AY289069 Genomic DNA. Translation: AAP48121.1.
AY289073 Genomic DNA. Translation: AAP48173.1.
AY289076 Genomic DNA. Translation: AAP48212.1.
AY289077 Genomic DNA. Translation: AAP48225.1.
AY289080 Genomic DNA. Translation: AAP48264.1.
AY289083 Genomic DNA. Translation: AAP48303.1.
AY289084 Genomic DNA. Translation: AAP48316.1.
AY289086 Genomic DNA. Translation: AAP48342.1.
AY289087 Genomic DNA. Translation: AAP48355.1.
AY289088 Genomic DNA. Translation: AAP48368.1.
AY289091 Genomic DNA. Translation: AAP48407.1.
AY289092 Genomic DNA. Translation: AAP48420.1.
AY289093 Genomic DNA. Translation: AAP48432.1.
AY289094 Genomic DNA. Translation: AAP48445.1.
AY289095 Genomic DNA. Translation: AAP48458.1.
AY289096 Genomic DNA. Translation: AAP48471.1.
AY289099 Genomic DNA. Translation: AAP48510.1.
AY289100 Genomic DNA. Translation: AAP48523.1.
AY289101 Genomic DNA. Translation: AAP48536.1.
AY289102 Genomic DNA. Translation: AAP48549.1.
AY495090 Genomic DNA. Translation: AAR92503.1.
AY495091 Genomic DNA. Translation: AAR92516.1.
AY495092 Genomic DNA. Translation: AAR92529.1.
AY495093 Genomic DNA. Translation: AAR92542.1.
AY495094 Genomic DNA. Translation: AAR92555.1.
AY495095 Genomic DNA. Translation: AAR92568.1.
AY495096 Genomic DNA. Translation: AAR92581.1.
AY495097 Genomic DNA. Translation: AAR92594.1.
AY495098 Genomic DNA. Translation: AAR92607.1.
AY495099 Genomic DNA. Translation: AAR92620.1.
AY495100 Genomic DNA. Translation: AAR92633.1.
AY495101 Genomic DNA. Translation: AAR92646.1.
AY495102 Genomic DNA. Translation: AAR92659.1.
AY495103 Genomic DNA. Translation: AAR92672.1.
AY495104 Genomic DNA. Translation: AAR92685.1.
AY495105 Genomic DNA. Translation: AAR92698.1.
AY495106 Genomic DNA. Translation: AAR92711.1.
AY495107 Genomic DNA. Translation: AAR92724.1.
AY495108 Genomic DNA. Translation: AAR92737.1.
AY495109 Genomic DNA. Translation: AAR92750.1.
AY495110 Genomic DNA. Translation: AAR92763.1.
AY495111 Genomic DNA. Translation: AAR92776.1.
AY495112 Genomic DNA. Translation: AAR92789.1.
AY495113 Genomic DNA. Translation: AAR92802.1.
AY495114 Genomic DNA. Translation: AAR92815.1.
AY495115 Genomic DNA. Translation: AAR92828.1.
AY495116 Genomic DNA. Translation: AAR92841.1.
AY495117 Genomic DNA. Translation: AAR92854.1.
AY495118 Genomic DNA. Translation: AAR92867.1.
AY495119 Genomic DNA. Translation: AAR92880.1.
AY495120 Genomic DNA. Translation: AAR92893.1.
AY495121 Genomic DNA. Translation: AAR92906.1.
AY495122 Genomic DNA. Translation: AAR92919.1.
AY495123 Genomic DNA. Translation: AAR92932.1.
AY495124 Genomic DNA. Translation: AAR92945.1.
AY495125 Genomic DNA. Translation: AAR92958.1.
AY495126 Genomic DNA. Translation: AAR92971.1.
AY495127 Genomic DNA. Translation: AAR92984.1.
AY495128 Genomic DNA. Translation: AAR92997.1.
AY495129 Genomic DNA. Translation: AAR93010.1.
AY495130 Genomic DNA. Translation: AAR93023.1.
AY495131 Genomic DNA. Translation: AAR93036.1.
AY495132 Genomic DNA. Translation: AAR93049.1.
AY495133 Genomic DNA. Translation: AAR93062.1.
AY495134 Genomic DNA. Translation: AAR93075.1.
AY495135 Genomic DNA. Translation: AAR93088.1.
AY495136 Genomic DNA. Translation: AAR93101.1.
AY495137 Genomic DNA. Translation: AAR93114.1.
AY495138 Genomic DNA. Translation: AAR93127.1.
AY495139 Genomic DNA. Translation: AAR93140.1.
AY495140 Genomic DNA. Translation: AAR93153.1.
AY495141 Genomic DNA. Translation: AAR93166.1.
AY495142 Genomic DNA. Translation: AAR93179.1.
AY495143 Genomic DNA. Translation: AAR93192.1.
AY495144 Genomic DNA. Translation: AAR93205.1.
AY495145 Genomic DNA. Translation: AAR93218.1.
AY495146 Genomic DNA. Translation: AAR93231.1.
AY495147 Genomic DNA. Translation: AAR93244.1.
AY495148 Genomic DNA. Translation: AAR93257.1.
AY495149 Genomic DNA. Translation: AAR93270.1.
AY495150 Genomic DNA. Translation: AAR93283.1.
AY495151 Genomic DNA. Translation: AAR93296.1.
AY495152 Genomic DNA. Translation: AAR93309.1.
AY495153 Genomic DNA. Translation: AAR93322.1.
AY495154 Genomic DNA. Translation: AAR93335.1.
AY495155 Genomic DNA. Translation: AAR93348.1.
AY495156 Genomic DNA. Translation: AAR93361.1.
AY495157 Genomic DNA. Translation: AAR93374.1.
AY495158 Genomic DNA. Translation: AAR93387.1.
AY495159 Genomic DNA. Translation: AAR93400.1.
AY495160 Genomic DNA. Translation: AAR93413.1.
AY495161 Genomic DNA. Translation: AAR93426.1.
AY495162 Genomic DNA. Translation: AAR93439.1.
AY495163 Genomic DNA. Translation: AAR93452.1.
AY495164 Genomic DNA. Translation: AAR93465.1.
AY495165 Genomic DNA. Translation: AAR93478.1.
AY495166 Genomic DNA. Translation: AAR93491.1.
AY495167 Genomic DNA. Translation: AAR93504.1.
AY495168 Genomic DNA. Translation: AAR93517.1.
AY495169 Genomic DNA. Translation: AAR93530.1.
AY495171 Genomic DNA. Translation: AAR93556.1.
AY495172 Genomic DNA. Translation: AAR93569.1.
AY495173 Genomic DNA. Translation: AAR93582.1.
AY495174 Genomic DNA. Translation: AAR93595.1.
AY495175 Genomic DNA. Translation: AAR93608.1.
AY495176 Genomic DNA. Translation: AAR93621.1.
AY495177 Genomic DNA. Translation: AAR93634.1.
AY495178 Genomic DNA. Translation: AAR93647.1.
AY495179 Genomic DNA. Translation: AAR93660.1.
AY495180 Genomic DNA. Translation: AAR93673.1.
AY495181 Genomic DNA. Translation: AAR93686.1.
AY495182 Genomic DNA. Translation: AAR93699.1.
AY495183 Genomic DNA. Translation: AAR93712.1.
AY495184 Genomic DNA. Translation: AAR93725.1.
AY495185 Genomic DNA. Translation: AAR93738.1.
AY495186 Genomic DNA. Translation: AAR93751.1.
AY495187 Genomic DNA. Translation: AAR93764.1.
AY495188 Genomic DNA. Translation: AAR93777.1.
AY495189 Genomic DNA. Translation: AAR93790.1.
AY495190 Genomic DNA. Translation: AAR93803.1.
AY495191 Genomic DNA. Translation: AAR93816.1.
AY495192 Genomic DNA. Translation: AAR93829.1.
AY495193 Genomic DNA. Translation: AAR93842.1.
AY495194 Genomic DNA. Translation: AAR93855.1.
AY495239 Genomic DNA. Translation: AAR94440.1.
AY495240 Genomic DNA. Translation: AAR94453.1.
AY495241 Genomic DNA. Translation: AAR94466.1.
AY495242 Genomic DNA. Translation: AAR94479.1.
AY495244 Genomic DNA. Translation: AAR94505.1.
AY495246 Genomic DNA. Translation: AAR94531.1.
AY495247 Genomic DNA. Translation: AAR94544.1.
AY495248 Genomic DNA. Translation: AAR94557.1.
AY495249 Genomic DNA. Translation: AAR94570.1.
AY495252 Genomic DNA. Translation: AAR94609.1.
AY495267 Genomic DNA. Translation: AAR94804.1.
AY495268 Genomic DNA. Translation: AAR94817.1.
AY495269 Genomic DNA. Translation: AAR94830.1.
AY495270 Genomic DNA. Translation: AAR94843.1.
AY495271 Genomic DNA. Translation: AAR94856.1.
AY495272 Genomic DNA. Translation: AAR94869.1.
AY495273 Genomic DNA. Translation: AAR94882.1.
AY495274 Genomic DNA. Translation: AAR94895.1.
AY495275 Genomic DNA. Translation: AAR94908.1.
AY495276 Genomic DNA. Translation: AAR94921.1.
AY495277 Genomic DNA. Translation: AAR94934.1.
AY495278 Genomic DNA. Translation: AAR94947.1.
AY495279 Genomic DNA. Translation: AAR94960.1.
AY495280 Genomic DNA. Translation: AAR94973.1.
AY495281 Genomic DNA. Translation: AAR94986.1.
AY495282 Genomic DNA. Translation: AAR94999.1.
AY495283 Genomic DNA. Translation: AAR95012.1.
AY495284 Genomic DNA. Translation: AAR95025.1.
AY495285 Genomic DNA. Translation: AAR95038.1.
AY495286 Genomic DNA. Translation: AAR95051.1.
AY495287 Genomic DNA. Translation: AAR95064.1.
AY495288 Genomic DNA. Translation: AAR95077.1.
AY495289 Genomic DNA. Translation: AAR95090.1.
AY495290 Genomic DNA. Translation: AAR95103.1.
AY495291 Genomic DNA. Translation: AAR95116.1.
AY495292 Genomic DNA. Translation: AAR95129.1.
AY495293 Genomic DNA. Translation: AAR95142.1.
AY495294 Genomic DNA. Translation: AAR95155.1.
AY495295 Genomic DNA. Translation: AAR95168.1.
AY495297 Genomic DNA. Translation: AAR95194.1.
AY495298 Genomic DNA. Translation: AAR95207.1.
AY495299 Genomic DNA. Translation: AAR95220.1.
AY495300 Genomic DNA. Translation: AAR95233.1.
AY495301 Genomic DNA. Translation: AAR95246.1.
AY495302 Genomic DNA. Translation: AAR95259.1.
AY495303 Genomic DNA. Translation: AAR95272.1.
AY495304 Genomic DNA. Translation: AAR95285.1.
AY495305 Genomic DNA. Translation: AAR95298.1.
AY495306 Genomic DNA. Translation: AAR95311.1.
AY495307 Genomic DNA. Translation: AAR95324.1.
AY495308 Genomic DNA. Translation: AAR95337.1.
AY495309 Genomic DNA. Translation: AAR95350.1.
AY495310 Genomic DNA. Translation: AAR95363.1.
AY495311 Genomic DNA. Translation: AAR95376.1.
AY495312 Genomic DNA. Translation: AAR95389.1.
AY495313 Genomic DNA. Translation: AAR95402.1.
AY495314 Genomic DNA. Translation: AAR95415.1.
AY495315 Genomic DNA. Translation: AAR95428.1.
AY495316 Genomic DNA. Translation: AAR95441.1.
AY495317 Genomic DNA. Translation: AAR95454.1.
AY495318 Genomic DNA. Translation: AAR95467.1.
AY495319 Genomic DNA. Translation: AAR95480.1.
AY495320 Genomic DNA. Translation: AAR95493.1.
AY495321 Genomic DNA. Translation: AAR95506.1.
AY495322 Genomic DNA. Translation: AAR95519.1.
AY495323 Genomic DNA. Translation: AAR95532.1.
AY495324 Genomic DNA. Translation: AAR95545.1.
AY495325 Genomic DNA. Translation: AAR95558.1.
AY495326 Genomic DNA. Translation: AAR95571.1.
AY495327 Genomic DNA. Translation: AAR95584.1.
AY495328 Genomic DNA. Translation: AAR95597.1.
AY495329 Genomic DNA. Translation: AAR95610.1.
AY495330 Genomic DNA. Translation: AAR95623.1.
PIRiA00422. DNHUN3.
RefSeqiYP_003024033.1. NC_012920.1.

Genome annotation databases

EnsembliENST00000361227; ENSP00000355206; ENSG00000198840.
GeneIDi4537.
KEGGihsa:4537.

Polymorphism databases

DMDMi128710.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
J01415 Genomic DNA. Translation: AAB58950.1 .
V00662 Genomic DNA. Translation: CAA24033.1 .
AY339402 Genomic DNA. Translation: AAP89043.1 .
AY339403 Genomic DNA. Translation: AAP89056.1 .
AY339404 Genomic DNA. Translation: AAP89069.1 .
AY339405 Genomic DNA. Translation: AAP89082.1 .
AY339406 Genomic DNA. Translation: AAP89095.1 .
AY339407 Genomic DNA. Translation: AAP89108.1 .
AY339408 Genomic DNA. Translation: AAP89121.1 .
AY339409 Genomic DNA. Translation: AAP89134.1 .
AY339410 Genomic DNA. Translation: AAP89147.1 .
AY339411 Genomic DNA. Translation: AAP89160.1 .
AY339412 Genomic DNA. Translation: AAP89173.1 .
AY339413 Genomic DNA. Translation: AAP89186.1 .
AY339414 Genomic DNA. Translation: AAP89199.1 .
AY339415 Genomic DNA. Translation: AAP89212.1 .
AY339416 Genomic DNA. Translation: AAP89225.1 .
AY339417 Genomic DNA. Translation: AAP89238.1 .
AY339418 Genomic DNA. Translation: AAP89251.1 .
AY339419 Genomic DNA. Translation: AAP89264.1 .
AY339420 Genomic DNA. Translation: AAP89277.1 .
AY339421 Genomic DNA. Translation: AAP89290.1 .
AY339422 Genomic DNA. Translation: AAP89303.1 .
AY339423 Genomic DNA. Translation: AAP89316.1 .
AY339424 Genomic DNA. Translation: AAP89329.1 .
AY339425 Genomic DNA. Translation: AAP89342.1 .
AY339426 Genomic DNA. Translation: AAP89355.1 .
AY339427 Genomic DNA. Translation: AAP89368.1 .
AY339428 Genomic DNA. Translation: AAP89381.1 .
AY339429 Genomic DNA. Translation: AAP89394.1 .
AY339430 Genomic DNA. Translation: AAP89407.1 .
AY339431 Genomic DNA. Translation: AAP89420.1 .
AY339432 Genomic DNA. Translation: AAP89433.1 .
AY339433 Genomic DNA. Translation: AAP89446.1 .
AY339434 Genomic DNA. Translation: AAP89459.1 .
AY339435 Genomic DNA. Translation: AAP89472.1 .
AY339436 Genomic DNA. Translation: AAP89485.1 .
AY339437 Genomic DNA. Translation: AAP89498.1 .
AY339438 Genomic DNA. Translation: AAP89511.1 .
AY339439 Genomic DNA. Translation: AAP89524.1 .
AY339440 Genomic DNA. Translation: AAP89537.1 .
AY339441 Genomic DNA. Translation: AAP89550.1 .
AY339442 Genomic DNA. Translation: AAP89563.1 .
AY339443 Genomic DNA. Translation: AAP89576.1 .
AY339444 Genomic DNA. Translation: AAP89589.1 .
AY339445 Genomic DNA. Translation: AAP89602.1 .
AY339446 Genomic DNA. Translation: AAP89615.1 .
AY339447 Genomic DNA. Translation: AAP89628.1 .
AY339448 Genomic DNA. Translation: AAP89641.1 .
AY339449 Genomic DNA. Translation: AAP89654.1 .
AY339450 Genomic DNA. Translation: AAP89667.1 .
AY339451 Genomic DNA. Translation: AAP89680.1 .
AY339452 Genomic DNA. Translation: AAP89693.1 .
AY339453 Genomic DNA. Translation: AAP89706.1 .
AY339454 Genomic DNA. Translation: AAP89719.1 .
AY339455 Genomic DNA. Translation: AAP89732.1 .
AY339456 Genomic DNA. Translation: AAP89745.1 .
AY339457 Genomic DNA. Translation: AAP89758.1 .
AY339458 Genomic DNA. Translation: AAP89771.1 .
AY339459 Genomic DNA. Translation: AAP89784.1 .
AY339460 Genomic DNA. Translation: AAP89797.1 .
AY339461 Genomic DNA. Translation: AAP89810.1 .
AY339462 Genomic DNA. Translation: AAP89823.1 .
AY339463 Genomic DNA. Translation: AAP89836.1 .
AY339464 Genomic DNA. Translation: AAP89849.1 .
AY339465 Genomic DNA. Translation: AAP89862.1 .
AY339475 Genomic DNA. Translation: AAP89992.1 .
AY339476 Genomic DNA. Translation: AAP90005.1 .
AY339477 Genomic DNA. Translation: AAP90018.1 .
AY339478 Genomic DNA. Translation: AAP90031.1 .
AY339479 Genomic DNA. Translation: AAP90044.1 .
AY339480 Genomic DNA. Translation: AAP90057.1 .
AY339481 Genomic DNA. Translation: AAP90070.1 .
AY339482 Genomic DNA. Translation: AAP90083.1 .
AY339483 Genomic DNA. Translation: AAP90096.1 .
AY339484 Genomic DNA. Translation: AAP90109.1 .
AY339485 Genomic DNA. Translation: AAP90122.1 .
AY339486 Genomic DNA. Translation: AAP90135.1 .
AY339487 Genomic DNA. Translation: AAP90148.1 .
AY339488 Genomic DNA. Translation: AAP90161.1 .
AY339489 Genomic DNA. Translation: AAP90174.1 .
AY339490 Genomic DNA. Translation: AAP90187.1 .
AY339491 Genomic DNA. Translation: AAP90200.1 .
AY339492 Genomic DNA. Translation: AAP90213.1 .
AY339493 Genomic DNA. Translation: AAP90226.1 .
AY339494 Genomic DNA. Translation: AAP90239.1 .
AY339495 Genomic DNA. Translation: AAP90252.1 .
AY339496 Genomic DNA. Translation: AAP90265.1 .
AY339510 Genomic DNA. Translation: AAP90447.1 .
AY339511 Genomic DNA. Translation: AAP90460.1 .
AY339512 Genomic DNA. Translation: AAP90473.1 .
AY339513 Genomic DNA. Translation: AAP90486.1 .
AY339523 Genomic DNA. Translation: AAP90616.1 .
AY339524 Genomic DNA. Translation: AAP90629.1 .
AY339525 Genomic DNA. Translation: AAP90642.1 .
AY339526 Genomic DNA. Translation: AAP90655.1 .
AY339527 Genomic DNA. Translation: AAP90668.1 .
AY339528 Genomic DNA. Translation: AAP90681.1 .
AY339529 Genomic DNA. Translation: AAP90694.1 .
AY339530 Genomic DNA. Translation: AAP90707.1 .
AY339531 Genomic DNA. Translation: AAP90720.1 .
AY339532 Genomic DNA. Translation: AAP90733.1 .
AY339533 Genomic DNA. Translation: AAP90746.1 .
AY339534 Genomic DNA. Translation: AAP90759.1 .
AY339535 Genomic DNA. Translation: AAP90772.1 .
AY339536 Genomic DNA. Translation: AAP90785.1 .
AY339537 Genomic DNA. Translation: AAP90798.1 .
AY339538 Genomic DNA. Translation: AAP90811.1 .
AY339539 Genomic DNA. Translation: AAP90824.1 .
AY339540 Genomic DNA. Translation: AAP90837.1 .
AY339541 Genomic DNA. Translation: AAP90850.1 .
AY339542 Genomic DNA. Translation: AAP90863.1 .
AY339543 Genomic DNA. Translation: AAP90876.1 .
AY339544 Genomic DNA. Translation: AAP90889.1 .
AY339545 Genomic DNA. Translation: AAP90902.1 .
AY339546 Genomic DNA. Translation: AAP90915.1 .
AY339549 Genomic DNA. Translation: AAP90954.1 .
AY339550 Genomic DNA. Translation: AAP90967.1 .
AY339551 Genomic DNA. Translation: AAP90980.1 .
AY339552 Genomic DNA. Translation: AAP90993.1 .
AY339553 Genomic DNA. Translation: AAP91006.1 .
AY339566 Genomic DNA. Translation: AAP91175.1 .
AY339567 Genomic DNA. Translation: AAP91188.1 .
AY339568 Genomic DNA. Translation: AAP91201.1 .
AY339569 Genomic DNA. Translation: AAP91214.1 .
AY339570 Genomic DNA. Translation: AAP91227.1 .
AY339571 Genomic DNA. Translation: AAP91240.1 .
AY339572 Genomic DNA. Translation: AAP91253.1 .
AY339573 Genomic DNA. Translation: AAP91266.1 .
AY339574 Genomic DNA. Translation: AAP91279.1 .
AF346963 Genomic DNA. Translation: AAK17214.1 .
AF346964 Genomic DNA. Translation: AAK17227.2 .
AF346971 Genomic DNA. Translation: AAK17318.2 .
AF346973 Genomic DNA. Translation: AAK17344.2 .
AF346974 Genomic DNA. Translation: AAK17357.2 .
AF346975 Genomic DNA. Translation: AAK17370.2 .
AF346978 Genomic DNA. Translation: AAK17409.1 .
AF346981 Genomic DNA. Translation: AAK17448.2 .
AF346982 Genomic DNA. Translation: AAK17461.1 .
AF346988 Genomic DNA. Translation: AAK17539.1 .
AF346993 Genomic DNA. Translation: AAK17604.2 .
AF347001 Genomic DNA. Translation: AAK17708.2 .
AF347002 Genomic DNA. Translation: AAK17721.2 .
AF347004 Genomic DNA. Translation: AAK17747.2 .
AF347005 Genomic DNA. Translation: AAK17760.2 .
AF347006 Genomic DNA. Translation: AAK17773.2 .
AF347007 Genomic DNA. Translation: AAK17786.2 .
AF347011 Genomic DNA. Translation: AAK17838.2 .
AY289051 Genomic DNA. Translation: AAP47887.1 .
AY289052 Genomic DNA. Translation: AAP47900.1 .
AY289053 Genomic DNA. Translation: AAP47913.1 .
AY289054 Genomic DNA. Translation: AAP47926.1 .
AY289055 Genomic DNA. Translation: AAP47939.1 .
AY289056 Genomic DNA. Translation: AAP47952.1 .
AY289058 Genomic DNA. Translation: AAP47978.1 .
AY289059 Genomic DNA. Translation: AAP47991.1 .
AY289060 Genomic DNA. Translation: AAP48004.1 .
AY289061 Genomic DNA. Translation: AAP48017.1 .
AY289062 Genomic DNA. Translation: AAP48030.1 .
AY289063 Genomic DNA. Translation: AAP48043.1 .
AY289065 Genomic DNA. Translation: AAP48069.1 .
AY289068 Genomic DNA. Translation: AAP48108.1 .
AY289069 Genomic DNA. Translation: AAP48121.1 .
AY289073 Genomic DNA. Translation: AAP48173.1 .
AY289076 Genomic DNA. Translation: AAP48212.1 .
AY289077 Genomic DNA. Translation: AAP48225.1 .
AY289080 Genomic DNA. Translation: AAP48264.1 .
AY289083 Genomic DNA. Translation: AAP48303.1 .
AY289084 Genomic DNA. Translation: AAP48316.1 .
AY289086 Genomic DNA. Translation: AAP48342.1 .
AY289087 Genomic DNA. Translation: AAP48355.1 .
AY289088 Genomic DNA. Translation: AAP48368.1 .
AY289091 Genomic DNA. Translation: AAP48407.1 .
AY289092 Genomic DNA. Translation: AAP48420.1 .
AY289093 Genomic DNA. Translation: AAP48432.1 .
AY289094 Genomic DNA. Translation: AAP48445.1 .
AY289095 Genomic DNA. Translation: AAP48458.1 .
AY289096 Genomic DNA. Translation: AAP48471.1 .
AY289099 Genomic DNA. Translation: AAP48510.1 .
AY289100 Genomic DNA. Translation: AAP48523.1 .
AY289101 Genomic DNA. Translation: AAP48536.1 .
AY289102 Genomic DNA. Translation: AAP48549.1 .
AY495090 Genomic DNA. Translation: AAR92503.1 .
AY495091 Genomic DNA. Translation: AAR92516.1 .
AY495092 Genomic DNA. Translation: AAR92529.1 .
AY495093 Genomic DNA. Translation: AAR92542.1 .
AY495094 Genomic DNA. Translation: AAR92555.1 .
AY495095 Genomic DNA. Translation: AAR92568.1 .
AY495096 Genomic DNA. Translation: AAR92581.1 .
AY495097 Genomic DNA. Translation: AAR92594.1 .
AY495098 Genomic DNA. Translation: AAR92607.1 .
AY495099 Genomic DNA. Translation: AAR92620.1 .
AY495100 Genomic DNA. Translation: AAR92633.1 .
AY495101 Genomic DNA. Translation: AAR92646.1 .
AY495102 Genomic DNA. Translation: AAR92659.1 .
AY495103 Genomic DNA. Translation: AAR92672.1 .
AY495104 Genomic DNA. Translation: AAR92685.1 .
AY495105 Genomic DNA. Translation: AAR92698.1 .
AY495106 Genomic DNA. Translation: AAR92711.1 .
AY495107 Genomic DNA. Translation: AAR92724.1 .
AY495108 Genomic DNA. Translation: AAR92737.1 .
AY495109 Genomic DNA. Translation: AAR92750.1 .
AY495110 Genomic DNA. Translation: AAR92763.1 .
AY495111 Genomic DNA. Translation: AAR92776.1 .
AY495112 Genomic DNA. Translation: AAR92789.1 .
AY495113 Genomic DNA. Translation: AAR92802.1 .
AY495114 Genomic DNA. Translation: AAR92815.1 .
AY495115 Genomic DNA. Translation: AAR92828.1 .
AY495116 Genomic DNA. Translation: AAR92841.1 .
AY495117 Genomic DNA. Translation: AAR92854.1 .
AY495118 Genomic DNA. Translation: AAR92867.1 .
AY495119 Genomic DNA. Translation: AAR92880.1 .
AY495120 Genomic DNA. Translation: AAR92893.1 .
AY495121 Genomic DNA. Translation: AAR92906.1 .
AY495122 Genomic DNA. Translation: AAR92919.1 .
AY495123 Genomic DNA. Translation: AAR92932.1 .
AY495124 Genomic DNA. Translation: AAR92945.1 .
AY495125 Genomic DNA. Translation: AAR92958.1 .
AY495126 Genomic DNA. Translation: AAR92971.1 .
AY495127 Genomic DNA. Translation: AAR92984.1 .
AY495128 Genomic DNA. Translation: AAR92997.1 .
AY495129 Genomic DNA. Translation: AAR93010.1 .
AY495130 Genomic DNA. Translation: AAR93023.1 .
AY495131 Genomic DNA. Translation: AAR93036.1 .
AY495132 Genomic DNA. Translation: AAR93049.1 .
AY495133 Genomic DNA. Translation: AAR93062.1 .
AY495134 Genomic DNA. Translation: AAR93075.1 .
AY495135 Genomic DNA. Translation: AAR93088.1 .
AY495136 Genomic DNA. Translation: AAR93101.1 .
AY495137 Genomic DNA. Translation: AAR93114.1 .
AY495138 Genomic DNA. Translation: AAR93127.1 .
AY495139 Genomic DNA. Translation: AAR93140.1 .
AY495140 Genomic DNA. Translation: AAR93153.1 .
AY495141 Genomic DNA. Translation: AAR93166.1 .
AY495142 Genomic DNA. Translation: AAR93179.1 .
AY495143 Genomic DNA. Translation: AAR93192.1 .
AY495144 Genomic DNA. Translation: AAR93205.1 .
AY495145 Genomic DNA. Translation: AAR93218.1 .
AY495146 Genomic DNA. Translation: AAR93231.1 .
AY495147 Genomic DNA. Translation: AAR93244.1 .
AY495148 Genomic DNA. Translation: AAR93257.1 .
AY495149 Genomic DNA. Translation: AAR93270.1 .
AY495150 Genomic DNA. Translation: AAR93283.1 .
AY495151 Genomic DNA. Translation: AAR93296.1 .
AY495152 Genomic DNA. Translation: AAR93309.1 .
AY495153 Genomic DNA. Translation: AAR93322.1 .
AY495154 Genomic DNA. Translation: AAR93335.1 .
AY495155 Genomic DNA. Translation: AAR93348.1 .
AY495156 Genomic DNA. Translation: AAR93361.1 .
AY495157 Genomic DNA. Translation: AAR93374.1 .
AY495158 Genomic DNA. Translation: AAR93387.1 .
AY495159 Genomic DNA. Translation: AAR93400.1 .
AY495160 Genomic DNA. Translation: AAR93413.1 .
AY495161 Genomic DNA. Translation: AAR93426.1 .
AY495162 Genomic DNA. Translation: AAR93439.1 .
AY495163 Genomic DNA. Translation: AAR93452.1 .
AY495164 Genomic DNA. Translation: AAR93465.1 .
AY495165 Genomic DNA. Translation: AAR93478.1 .
AY495166 Genomic DNA. Translation: AAR93491.1 .
AY495167 Genomic DNA. Translation: AAR93504.1 .
AY495168 Genomic DNA. Translation: AAR93517.1 .
AY495169 Genomic DNA. Translation: AAR93530.1 .
AY495171 Genomic DNA. Translation: AAR93556.1 .
AY495172 Genomic DNA. Translation: AAR93569.1 .
AY495173 Genomic DNA. Translation: AAR93582.1 .
AY495174 Genomic DNA. Translation: AAR93595.1 .
AY495175 Genomic DNA. Translation: AAR93608.1 .
AY495176 Genomic DNA. Translation: AAR93621.1 .
AY495177 Genomic DNA. Translation: AAR93634.1 .
AY495178 Genomic DNA. Translation: AAR93647.1 .
AY495179 Genomic DNA. Translation: AAR93660.1 .
AY495180 Genomic DNA. Translation: AAR93673.1 .
AY495181 Genomic DNA. Translation: AAR93686.1 .
AY495182 Genomic DNA. Translation: AAR93699.1 .
AY495183 Genomic DNA. Translation: AAR93712.1 .
AY495184 Genomic DNA. Translation: AAR93725.1 .
AY495185 Genomic DNA. Translation: AAR93738.1 .
AY495186 Genomic DNA. Translation: AAR93751.1 .
AY495187 Genomic DNA. Translation: AAR93764.1 .
AY495188 Genomic DNA. Translation: AAR93777.1 .
AY495189 Genomic DNA. Translation: AAR93790.1 .
AY495190 Genomic DNA. Translation: AAR93803.1 .
AY495191 Genomic DNA. Translation: AAR93816.1 .
AY495192 Genomic DNA. Translation: AAR93829.1 .
AY495193 Genomic DNA. Translation: AAR93842.1 .
AY495194 Genomic DNA. Translation: AAR93855.1 .
AY495239 Genomic DNA. Translation: AAR94440.1 .
AY495240 Genomic DNA. Translation: AAR94453.1 .
AY495241 Genomic DNA. Translation: AAR94466.1 .
AY495242 Genomic DNA. Translation: AAR94479.1 .
AY495244 Genomic DNA. Translation: AAR94505.1 .
AY495246 Genomic DNA. Translation: AAR94531.1 .
AY495247 Genomic DNA. Translation: AAR94544.1 .
AY495248 Genomic DNA. Translation: AAR94557.1 .
AY495249 Genomic DNA. Translation: AAR94570.1 .
AY495252 Genomic DNA. Translation: AAR94609.1 .
AY495267 Genomic DNA. Translation: AAR94804.1 .
AY495268 Genomic DNA. Translation: AAR94817.1 .
AY495269 Genomic DNA. Translation: AAR94830.1 .
AY495270 Genomic DNA. Translation: AAR94843.1 .
AY495271 Genomic DNA. Translation: AAR94856.1 .
AY495272 Genomic DNA. Translation: AAR94869.1 .
AY495273 Genomic DNA. Translation: AAR94882.1 .
AY495274 Genomic DNA. Translation: AAR94895.1 .
AY495275 Genomic DNA. Translation: AAR94908.1 .
AY495276 Genomic DNA. Translation: AAR94921.1 .
AY495277 Genomic DNA. Translation: AAR94934.1 .
AY495278 Genomic DNA. Translation: AAR94947.1 .
AY495279 Genomic DNA. Translation: AAR94960.1 .
AY495280 Genomic DNA. Translation: AAR94973.1 .
AY495281 Genomic DNA. Translation: AAR94986.1 .
AY495282 Genomic DNA. Translation: AAR94999.1 .
AY495283 Genomic DNA. Translation: AAR95012.1 .
AY495284 Genomic DNA. Translation: AAR95025.1 .
AY495285 Genomic DNA. Translation: AAR95038.1 .
AY495286 Genomic DNA. Translation: AAR95051.1 .
AY495287 Genomic DNA. Translation: AAR95064.1 .
AY495288 Genomic DNA. Translation: AAR95077.1 .
AY495289 Genomic DNA. Translation: AAR95090.1 .
AY495290 Genomic DNA. Translation: AAR95103.1 .
AY495291 Genomic DNA. Translation: AAR95116.1 .
AY495292 Genomic DNA. Translation: AAR95129.1 .
AY495293 Genomic DNA. Translation: AAR95142.1 .
AY495294 Genomic DNA. Translation: AAR95155.1 .
AY495295 Genomic DNA. Translation: AAR95168.1 .
AY495297 Genomic DNA. Translation: AAR95194.1 .
AY495298 Genomic DNA. Translation: AAR95207.1 .
AY495299 Genomic DNA. Translation: AAR95220.1 .
AY495300 Genomic DNA. Translation: AAR95233.1 .
AY495301 Genomic DNA. Translation: AAR95246.1 .
AY495302 Genomic DNA. Translation: AAR95259.1 .
AY495303 Genomic DNA. Translation: AAR95272.1 .
AY495304 Genomic DNA. Translation: AAR95285.1 .
AY495305 Genomic DNA. Translation: AAR95298.1 .
AY495306 Genomic DNA. Translation: AAR95311.1 .
AY495307 Genomic DNA. Translation: AAR95324.1 .
AY495308 Genomic DNA. Translation: AAR95337.1 .
AY495309 Genomic DNA. Translation: AAR95350.1 .
AY495310 Genomic DNA. Translation: AAR95363.1 .
AY495311 Genomic DNA. Translation: AAR95376.1 .
AY495312 Genomic DNA. Translation: AAR95389.1 .
AY495313 Genomic DNA. Translation: AAR95402.1 .
AY495314 Genomic DNA. Translation: AAR95415.1 .
AY495315 Genomic DNA. Translation: AAR95428.1 .
AY495316 Genomic DNA. Translation: AAR95441.1 .
AY495317 Genomic DNA. Translation: AAR95454.1 .
AY495318 Genomic DNA. Translation: AAR95467.1 .
AY495319 Genomic DNA. Translation: AAR95480.1 .
AY495320 Genomic DNA. Translation: AAR95493.1 .
AY495321 Genomic DNA. Translation: AAR95506.1 .
AY495322 Genomic DNA. Translation: AAR95519.1 .
AY495323 Genomic DNA. Translation: AAR95532.1 .
AY495324 Genomic DNA. Translation: AAR95545.1 .
AY495325 Genomic DNA. Translation: AAR95558.1 .
AY495326 Genomic DNA. Translation: AAR95571.1 .
AY495327 Genomic DNA. Translation: AAR95584.1 .
AY495328 Genomic DNA. Translation: AAR95597.1 .
AY495329 Genomic DNA. Translation: AAR95610.1 .
AY495330 Genomic DNA. Translation: AAR95623.1 .
PIRi A00422. DNHUN3.
RefSeqi YP_003024033.1. NC_012920.1.

3D structure databases

ProteinModelPortali P03897.
SMRi P03897. Positions 3-112.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P03897. 1 interaction.

Chemistry

BindingDBi P03897.
ChEMBLi CHEMBL2363065.

PTM databases

PhosphoSitei P03897.

Polymorphism databases

DMDMi 128710.

Proteomic databases

MaxQBi P03897.
PaxDbi P03897.
PRIDEi P03897.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000361227 ; ENSP00000355206 ; ENSG00000198840 .
GeneIDi 4537.
KEGGi hsa:4537.

Organism-specific databases

CTDi 4537.
GeneCardsi GCMTP010061.
GeneReviewsi MT-ND3.
HGNCi HGNC:7458. MT-ND3.
MIMi 252010. phenotype.
256000. phenotype.
516002. gene.
neXtProti NX_P03897.
Orphaneti 99718. Leber plus disease.
255210. Maternally-inherited Leigh syndrome.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG282870.
HOVERGENi HBG017392.
InParanoidi P03897.
KOi K03880.
OMAi TTNLPLM.
OrthoDBi EOG7RV9K7.
PhylomeDBi P03897.
TreeFami TF343336.

Enzyme and pathway databases

Reactomei REACT_22393. Respiratory electron transport.

Miscellaneous databases

GeneWikii MT-ND3.
GenomeRNAii 4537.
NextBioi 17502.
PROi P03897.
SOURCEi Search...

Gene expression databases

Bgeei P03897.
ExpressionAtlasi P03897. baseline.
Genevestigatori P03897.

Family and domain databases

InterProi IPR000440. NADH_UbQ/plastoQ_OxRdtase_su3.
[Graphical view ]
PANTHERi PTHR11058. PTHR11058. 1 hit.
Pfami PF00507. Oxidored_q4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Lineage-specific selection in human mtDNA: lack of polymorphisms in a segment of MTND5 gene in haplogroup J."
    Moilanen J.S., Finnila S., Majamaa K.
    Mol. Biol. Evol. 20:2132-2142(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Mitochondrial genome variation and the origin of modern humans."
    Ingman M., Kaessmann H., Paeaebo S., Gyllensten U.
    Nature 408:708-713(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  4. "Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines."
    Ingman M., Gyllensten U.
    Genome Res. 13:1600-1606(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  5. "Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians."
    Coble M.D., Just R.S., O'Callaghan J.E., Letmanyi I.H., Peterson C.T., Irwin J.A., Parsons T.J.
    Int. J. Legal Med. 118:137-146(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  6. "Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase."
    Chomyn A., Mariottini P., Cleeter M.W.J., Ragan C.I., Matsuno-Yagi A., Hatefi Y., Doolittle R.F., Attardi G.
    Nature 314:592-597(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF PROTEIN.
  7. "The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."
    Murray J., Zhang B., Taylor S.W., Oglesbee D., Fahy E., Marusich M.F., Ghosh S.S., Capaldi R.A.
    J. Biol. Chem. 278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  9. "Assignment of a polymorphic polypeptide to the human mitochondrial DNA unidentified reading frame 3 gene by a new peptide mapping strategy."
    Oliver N.A., Greenberg B.D., Wallace D.C.
    J. Biol. Chem. 258:5834-5839(1983) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS ASP-10 AND ALA-114.
  10. "Normal variants of human mitochondrial DNA and translation products: the building of a reference data base."
    Marzuki S., Noer A.S., Lertrit P., Thyagarajan D., Kapsa R., Utthanaphol P., Byrne E.
    Hum. Genet. 88:139-145(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS VAL-53 AND ALA-114.
  11. "Progressive mitochondrial disease resulting from a novel missense mutation in the mitochondrial DNA ND3 gene."
    Taylor R.W., Singh-Kler R., Hayes C.M., Smith P.E., Turnbull D.M.
    Ann. Neurol. 50:104-107(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANT MT-C1D PRO-45.
  12. "De novo mutations in the mitochondrial ND3 gene as a cause of infantile mitochondrial encephalopathy and complex I deficiency."
    McFarland R., Kirby D.M., Fowler K.J., Ohtake A., Ryan M.T., Amor D.J., Fletcher J.M., Dixon J.W., Collins F.A., Turnbull D.M., Taylor R.W., Thorburn D.R.
    Ann. Neurol. 55:58-64(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANT MT-C1D PRO-34.
  13. "A novel recurrent mitochondrial DNA mutation in ND3 gene is associated with isolated complex I deficiency causing Leigh syndrome and dystonia."
    Sarzi E., Brown M.D., Lebon S., Chretien D., Munnich A., Rotig A., Procaccio V.
    Am. J. Med. Genet. A 143:33-41(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANT LS THR-47.
  14. Cited for: VARIANTS MT-C1D PRO-34; PRO-45 AND THR-47.

Entry informationi

Entry nameiNU3M_HUMAN
AccessioniPrimary (citable) accession number: P03897
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 29, 2014
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3