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Protein

Putative COX1/OXI3 intron 2 protein

Gene

AI2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • aerobic respiration Source: InterPro
  • intron homing Source: SGD
  • mRNA processing Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-34373-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative COX1/OXI3 intron 2 protein
Gene namesi
Name:AI2
Ordered Locus Names:Q0055
Encoded oniMitochondrion
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Mitochondrion

Organism-specific databases

EuPathDBiFungiDB:Q0055.
SGDiS000007262. AI2.

Subcellular locationi

GO - Cellular componenti

  • integral component of membrane Source: InterPro
  • mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001968811 – 854Putative COX1/OXI3 intron 2 proteinAdd BLAST854

Proteomic databases

MaxQBiP03876.
PRIDEiP03876.

Interactioni

Protein-protein interaction databases

BioGridi34786. 3 interactors.

Structurei

3D structure databases

ProteinModelPortaliP03876.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini329 – 613Reverse transcriptasePROSITE-ProRule annotationAdd BLAST285

Sequence similaritiesi

Contains 1 reverse transcriptase domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00840000130858.
HOGENOMiHOG000172601.
InParanoidiP03876.
OMAiWYIKGDF.
OrthoDBiEOG092C608C.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR000883. COX1.
IPR023616. Cyt_c_oxase-like_su1_dom.
IPR024937. Domain_X.
IPR003615. HNH_nuc.
IPR000477. RT_dom.
[Graphical view]
PfamiPF01348. Intron_maturas2. 1 hit.
PF00078. RVT_1. 1 hit.
[Graphical view]
PRINTSiPR01165. CYCOXIDASEI.
SMARTiSM00507. HNHc. 1 hit.
[Graphical view]
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiPS50855. COX1. 1 hit.
PS50878. RT_POL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P03876-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
60 70 80 90 100
NSQLFNVLVV GHAVLMIFCA PFRLIYHCIE VLIDKHISVY SINENFTVSF
110 120 130 140 150
WFWLLVVTYM VFRYVNHMAY PVGANSTGTM ACHKSAGVKQ PAQGKNCPMA
160 170 180 190 200
RLTNSCKECL GFSLTPSHLG IVIHAYVLEE EVHELTKNES LALSKSWHLE
210 220 230 240 250
GCTSSNGKLR NTGLSERGNP GDNGVFMVPK FNLNKVRYFS TLSKLNARKE
260 270 280 290 300
DSLAYLTKIN TTDFSELNKL MENNHNKTET INTRILKLMS DIRMLLIAYN
310 320 330 340 350
KIKSKKGNMS KGSNNITLDG INISYLNKLS KDINTNMFKF SPVRRVEIPK
360 370 380 390 400
TSGGFRPLSV GNPREKIVQE SMRMMLEIIY NNSFSYYSHG FRPNLSCLTA
410 420 430 440 450
IIQCKNYMQY CNWFIKVDLN KCFDTIPHNM LINVLNERIK DKGFMDLLYK
460 470 480 490 500
LLRAGYVDKN NNYHNTTLGI PQGSVVSPIL CNIFLDKLDK YLENKFENEF
510 520 530 540 550
NTGNMSNRGR NPIYNSLSSK IYRCKLLSEK LKLIRLRDHY QRNMGSDKSF
560 570 580 590 600
KRAYFVRYAD DIIIGVMGSH NDCKNILNDI NNFLKENLGM SINMDKSVIK
610 620 630 640 650
HSKEGVSFLG YDVKVTPWEK RPYRMIKKGD NFIRVRHHTS LVVNAPIRSI
660 670 680 690 700
VMKLNKHGYC SHGILGKPRG VGRLIHEEMK TILMHYLAVG RGIMNYYRLA
710 720 730 740 750
TNFTTLRGRI TYILFYSCCL TLARKFKLNT VKKVILKFGK VLVDPHSKVS
760 770 780 790 800
FSIDDFKIRH KMNMTDSNYT PDEILDRYKY MLPRSLSLFS GICQICGSKH
810 820 830 840 850
DLEVHHVRTL NNAANKIKDD YLLGRMIKMN RKQITICKTC HFKVHQGKYN

GPGL
Length:854
Mass (Da):98,008
Last modified:December 20, 2005 - v2
Checksum:i6E22D9B5ABCD43F2
GO

Sequence cautioni

The sequence CAA24060 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti236V → A in CAA24060 (PubMed:6254986).Curated1
Sequence conflicti724R → S in CAA24060 (PubMed:6254986).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00694 Genomic DNA. Translation: CAA24060.1. Sequence problems.
KP263414 Genomic DNA. Translation: AIZ98885.1.
PIRiA04509. QXBY32.
S78644.
RefSeqiNP_009309.1. NC_001224.1.

Genome annotation databases

EnsemblFungiiQ0055; Q0055; Q0055.
GeneIDi854594.
KEGGisce:Q0055.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00694 Genomic DNA. Translation: CAA24060.1. Sequence problems.
KP263414 Genomic DNA. Translation: AIZ98885.1.
PIRiA04509. QXBY32.
S78644.
RefSeqiNP_009309.1. NC_001224.1.

3D structure databases

ProteinModelPortaliP03876.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34786. 3 interactors.

Proteomic databases

MaxQBiP03876.
PRIDEiP03876.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiQ0055; Q0055; Q0055.
GeneIDi854594.
KEGGisce:Q0055.

Organism-specific databases

EuPathDBiFungiDB:Q0055.
SGDiS000007262. AI2.

Phylogenomic databases

GeneTreeiENSGT00840000130858.
HOGENOMiHOG000172601.
InParanoidiP03876.
OMAiWYIKGDF.
OrthoDBiEOG092C608C.

Enzyme and pathway databases

BioCyciYEAST:G3O-34373-MONOMER.

Miscellaneous databases

PROiP03876.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR000883. COX1.
IPR023616. Cyt_c_oxase-like_su1_dom.
IPR024937. Domain_X.
IPR003615. HNH_nuc.
IPR000477. RT_dom.
[Graphical view]
PfamiPF01348. Intron_maturas2. 1 hit.
PF00078. RVT_1. 1 hit.
[Graphical view]
PRINTSiPR01165. CYCOXIDASEI.
SMARTiSM00507. HNHc. 1 hit.
[Graphical view]
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiPS50855. COX1. 1 hit.
PS50878. RT_POL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAI2M_YEAST
AccessioniPrimary (citable) accession number: P03876
Secondary accession number(s): A0A0A7NYJ2, Q9ZZX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: December 20, 2005
Last modified: November 30, 2016
This is version 129 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

This protein is coded in group-II intron 2 of OXI3 (COX1).

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.