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Protein

Putative COX1/OXI3 intron 1 protein

Gene

AI1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • cytochrome-c oxidase activity Source: InterPro
  • RNA-directed DNA polymerase activity Source: SGD

GO - Biological processi

  • homing of group II introns Source: SGD
  • mRNA processing Source: SGD
  • RNA-dependent DNA biosynthetic process Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-34372-MONOMER.

Protein family/group databases

REBASEi2622. I-SceIII.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative COX1/OXI3 intron 1 protein
Gene namesi
Name:AI1
Ordered Locus Names:Q0050
Encoded oniMitochondrion
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Mitochondrion

Organism-specific databases

EuPathDBiFungiDB:Q0050.
SGDiS000007261. AI1.

Subcellular locationi

GO - Cellular componenti

  • mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001968801 – 834Putative COX1/OXI3 intron 1 proteinAdd BLAST834

Proteomic databases

MaxQBiP03875.
PRIDEiP03875.

Interactioni

Protein-protein interaction databases

BioGridi34785. 6 interactors.
DIPiDIP-8242N.
MINTiMINT-690265.

Structurei

3D structure databases

ProteinModelPortaliP03875.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini296 – 577Reverse transcriptasePROSITE-ProRule annotationAdd BLAST282

Sequence similaritiesi

Contains 1 reverse transcriptase domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00840000130858.
HOGENOMiHOG000172601.
InParanoidiP03875.
OMAiITCATET.
OrthoDBiEOG092C47G1.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR023616. Cyt_c_oxase-like_su1_dom.
IPR024937. Domain_X.
IPR003615. HNH_nuc.
IPR000477. RT_dom.
[Graphical view]
PfamiPF01348. Intron_maturas2. 1 hit.
PF00078. RVT_1. 1 hit.
[Graphical view]
SMARTiSM00507. HNHc. 1 hit.
[Graphical view]
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiPS50878. RT_POL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P03875-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
60 70 80 90 100
NSQLFNGAPT SAYISLMRTA LVLWIINRYL KHMTNSVGAN FTGTMACHKT
110 120 130 140 150
PMISVGGVKC YMVRLTNFLQ VFIRITISSY HLDMVKQVWL FYVEVIRLWF
160 170 180 190 200
IVLDSTGSVK KMKDTNNTKG NTKSEGSTER GNSGVDRGMV VPNTQMKMRF
210 220 230 240 250
LNQVRYYSVN NNLKMGKDTN IELSKDTSTS DLLEFEKLVM DNMNEENMNN
260 270 280 290 300
NLLSIMKNVD MLMLAYNRIK SKPGNMTPGT TLETLDGMNM MYLNKLSNEL
310 320 330 340 350
GTGKFKFKPM RMVNIPKPKG GMRPLSVGNP RDKIVQEVMR MILDTIFDKK
360 370 380 390 400
MSTHSHGFRK NMSCQTAIWE VRNMFGGSNW FIEVDLKKCF DTISHDLIIK
410 420 430 440 450
ELKRYISDKG FIDLVYKLLR AGYIDEKGTY HKPMLGLPQG SLISPILCNI
460 470 480 490 500
VMTLVDNWLE DYINLYNKGK VKKQHPTYKK LSRMIAKAKM FSTRLKLHKE
510 520 530 540 550
RAKGPTFIYN DPNFKRMKYV RYADDILIGV LGSKNDCKMI KRDLNNFLNS
560 570 580 590 600
LGLTMNEEKT LITCATETPA RFLGYNISIT PLKRMPTVTK TIRGKTIRSR
610 620 630 640 650
NTTRPIINAP IRDIINKLAT NGYCKHNKNG RMGVPTRVGR WTYEEPRTII
660 670 680 690 700
NNYKALGRGI LNYYKLATNY KRLRERIYYV LYYSCVLTLA SKYRLKTMSK
710 720 730 740 750
TIKKFGYNLN IIENDKLIAN FPRNTFDNIK KIENHGMFMY MSEAKVTDPF
760 770 780 790 800
EYIDSIKYML PTAKANFNKP CSICNSTIDV EMHHVKQLHR GMLKATKDYI
810 820 830
TGRMITMNRK QIPLCKQCHI KTHKNKFKNM GPGM
Length:834
Mass (Da):96,079
Last modified:December 20, 2005 - v2
Checksum:iBFB64B6F36416A5A
GO

Sequence cautioni

The sequence CAA24071 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti118F → N (PubMed:6254986).Curated1
Sequence conflicti118F → N (PubMed:3549452).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00694 Genomic DNA. Translation: CAA24071.1. Different initiation.
L36897 Genomic DNA. Translation: AAA67532.1.
KP263414 Genomic DNA. Translation: AIZ98886.1.
PIRiA04508. QXBY31.
S78642.
RefSeqiNP_009310.1. NC_001224.1.

Genome annotation databases

EnsemblFungiiQ0050; Q0050; Q0050.
GeneIDi854593.
KEGGisce:Q0050.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00694 Genomic DNA. Translation: CAA24071.1. Different initiation.
L36897 Genomic DNA. Translation: AAA67532.1.
KP263414 Genomic DNA. Translation: AIZ98886.1.
PIRiA04508. QXBY31.
S78642.
RefSeqiNP_009310.1. NC_001224.1.

3D structure databases

ProteinModelPortaliP03875.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34785. 6 interactors.
DIPiDIP-8242N.
MINTiMINT-690265.

Protein family/group databases

REBASEi2622. I-SceIII.

Proteomic databases

MaxQBiP03875.
PRIDEiP03875.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiQ0050; Q0050; Q0050.
GeneIDi854593.
KEGGisce:Q0050.

Organism-specific databases

EuPathDBiFungiDB:Q0050.
SGDiS000007261. AI1.

Phylogenomic databases

GeneTreeiENSGT00840000130858.
HOGENOMiHOG000172601.
InParanoidiP03875.
OMAiITCATET.
OrthoDBiEOG092C47G1.

Enzyme and pathway databases

BioCyciYEAST:G3O-34372-MONOMER.

Miscellaneous databases

PROiP03875.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR023616. Cyt_c_oxase-like_su1_dom.
IPR024937. Domain_X.
IPR003615. HNH_nuc.
IPR000477. RT_dom.
[Graphical view]
PfamiPF01348. Intron_maturas2. 1 hit.
PF00078. RVT_1. 1 hit.
[Graphical view]
SMARTiSM00507. HNHc. 1 hit.
[Graphical view]
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiPS50878. RT_POL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAI1M_YEAST
AccessioniPrimary (citable) accession number: P03875
Secondary accession number(s): A0A0A7NYG1, Q9ZZX5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: December 20, 2005
Last modified: November 30, 2016
This is version 133 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

This protein is coded in group-II intron 1 of OXI3 (COX1).

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.