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Protein

Transposase InsG for insertion sequence element IS4

Gene

insG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the transposition of the insertion sequence IS4.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA recombination, Transposition

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7900-MONOMER.
ECOL316407:JW5767-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transposase InsG for insertion sequence element IS4
Gene namesi
Name:insG
Ordered Locus Names:b4278, JW5767
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG40007. insG.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 442442Transposase InsG for insertion sequence element IS4PRO_0000173291Add
BLAST

Proteomic databases

PaxDbiP03835.
PRIDEiP03835.

Interactioni

Protein-protein interaction databases

STRINGi511145.b4278.

Structurei

3D structure databases

ProteinModelPortaliP03835.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transposase 11 family.Curated

Phylogenomic databases

eggNOGiENOG4105VNT. Bacteria.
COG3385. LUCA.
HOGENOMiHOG000119822.
InParanoidiP03835.
KOiK07495.
OMAiTVFDKGF.
OrthoDBiEOG6384GM.
PhylomeDBiP03835.

Family and domain databases

InterProiIPR012337. RNaseH-like_dom.
IPR002559. Transposase_11.
IPR024473. Transposases_IS4_N.
[Graphical view]
PfamiPF01609. DDE_Tnp_1. 1 hit.
PF13006. Nterm_IS4. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

P03835-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHIGQALDLV SRYDSLRNPL TSLGDYLDPE LISRCLAESG TVTLRKRRLP
60 70 80 90 100
LEMMVWCIVG MALERKEPLH QIVNRLDIML PGNRPFVAPS AVIQARQRLG
110 120 130 140 150
SEAVRRVFTK TAQLWHNATP HPHWCGLTLL AIDGVFWRTP DTPENDAAFP
160 170 180 190 200
RQTHAGNPAL YPQVKMVCQM ELTSHLLTAA AFGTMKNSEN ELAEQLIEQT
210 220 230 240 250
GDNTLTLMDK GYYSLGLLNA WSLAGEHRHW MIPLRKGAQY EEIRKLGKGD
260 270 280 290 300
HLVKLKTSPQ ARKKWPGLGN EVTARLLTVT RKGKVCHLLT SMTDAMRFPG
310 320 330 340 350
GEMGDLYSHR WEIELGYREI KQTMQRSRLT LRSKKPELVE QELWGVLLAY
360 370 380 390 400
NLVRYQMIKM AEHLKGYWPN QLSFSESCGM VMRMLMTLQG ASPGRIPELM
410 420 430 440
RDLASMGQLV KLPTRRERAF PRVVKERPWK YPTAPKKSQS VA
Length:442
Mass (Da):50,386
Last modified:July 21, 1986 - v1
Checksum:i0B9CAAA0FFAC724E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01733 Genomic DNA. No translation available.
U14003 Genomic DNA. Translation: AAA97174.1.
U00096 Genomic DNA. Translation: AAC77234.1.
AP009048 Genomic DNA. Translation: BAE78272.1.
PIRiA04463. IEEC41.
RefSeqiNP_418698.1. NC_000913.3.
WP_000547191.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77234; AAC77234; b4278.
BAE78272; BAE78272; BAE78272.
GeneIDi948805.
KEGGiecj:JW5767.
eco:b4278.
PATRICi32124129. VBIEscCol129921_4408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01733 Genomic DNA. No translation available.
U14003 Genomic DNA. Translation: AAA97174.1.
U00096 Genomic DNA. Translation: AAC77234.1.
AP009048 Genomic DNA. Translation: BAE78272.1.
PIRiA04463. IEEC41.
RefSeqiNP_418698.1. NC_000913.3.
WP_000547191.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP03835.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi511145.b4278.

Proteomic databases

PaxDbiP03835.
PRIDEiP03835.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77234; AAC77234; b4278.
BAE78272; BAE78272; BAE78272.
GeneIDi948805.
KEGGiecj:JW5767.
eco:b4278.
PATRICi32124129. VBIEscCol129921_4408.

Organism-specific databases

EchoBASEiEB4735.
EcoGeneiEG40007. insG.

Phylogenomic databases

eggNOGiENOG4105VNT. Bacteria.
COG3385. LUCA.
HOGENOMiHOG000119822.
InParanoidiP03835.
KOiK07495.
OMAiTVFDKGF.
OrthoDBiEOG6384GM.
PhylomeDBiP03835.

Enzyme and pathway databases

BioCyciEcoCyc:G7900-MONOMER.
ECOL316407:JW5767-MONOMER.

Miscellaneous databases

PROiP03835.

Family and domain databases

InterProiIPR012337. RNaseH-like_dom.
IPR002559. Transposase_11.
IPR024473. Transposases_IS4_N.
[Graphical view]
PfamiPF01609. DDE_Tnp_1. 1 hit.
PF13006. Nterm_IS4. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. "Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
    Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
    Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiINSG_ECOLI
AccessioniPrimary (citable) accession number: P03835
Secondary accession number(s): Q2M634
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 11, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.