Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Overcome classical restriction gp0.3

Gene

0.3

Organism
Enterobacteria phage T7 (Bacteriophage T7)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Prevents both degradation and modification of T7 DNA by the host restriction-modification complex. Structural mimic of the phosphate backbone of B-form DNA that binds to and completely occupies the DNA-binding site of all guO21970. Thereby, inhibits the restriction endonuclease activity and protects the phage genome as it penetrates into host cytoplasm.2 Publications

GO - Biological processi

Keywordsi

Biological processHost-virus interaction, Restriction-modification system evasion by virus

Names & Taxonomyi

Protein namesi
Recommended name:
Overcome classical restriction gp0.3
Alternative name(s):
Gene product 0.3
Short name:
Gp0.3
OCR
Gene namesi
Ordered Locus Names:0.3
OrganismiEnterobacteria phage T7 (Bacteriophage T7)
Taxonomic identifieri10760 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000000840 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001064621 – 117Overcome classical restriction gp0.3Add BLAST117

Expressioni

Keywords - Developmental stagei

Early protein

Interactioni

Subunit structurei

Homodimer. Interacts with host type I restriction enzyme EcoKI M protein/HsdM.2 Publications

Protein-protein interaction databases

IntActiP03775, 1 interactor
MINTiP03775

Structurei

Secondary structure

1117
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi8 – 25Combined sources18
Helixi31 – 33Combined sources3
Helixi35 – 45Combined sources11
Helixi50 – 57Combined sources8
Helixi69 – 71Combined sources3
Helixi78 – 96Combined sources19
Helixi98 – 106Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1S7ZX-ray1.83A1-117[»]
2Y7Celectron microscopy18.00D/E1-116[»]
ProteinModelPortaliP03775
SMRiP03775
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP03775

Family & Domainsi

Phylogenomic databases

OrthoDBiVOG090001NG

Family and domain databases

Gene3Di1.20.120.780, 1 hit
InterProiView protein in InterPro
IPR036207 B-form_Ocr
IPR014798 Ocr
PfamiView protein in Pfam
PF08684 ocr, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD069042 Ocr, 1 hit
SUPFAMiSSF101059 SSF101059, 1 hit

Sequencei

Sequence statusi: Complete.

P03775-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMSNMTYNN VFDHAYEMLK ENIRYDDIRD TDDLHDAIHM AADNAVPHYY
60 70 80 90 100
ADIFSVMASE GIDLEFEDSG LMPDTKDVIR ILQARIYEQL TIDLWEDAED
110
LLNEYLEEVE EYEEDEE
Length:117
Mass (Da):13,809
Last modified:July 21, 1986 - v1
Checksum:iBB7D3D45068EB17D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti43D → S in AAA32564 (Ref. 3) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M38334 Genomic DNA Translation: AAA32564.1
V01146 Genomic DNA Translation: CAA24384.1
V01127 Genomic DNA Translation: CAA24327.1
PIRiA43002 W0BP37
RefSeqiNP_041954.1, NC_001604.1

Genome annotation databases

GeneIDi1261063
KEGGivg:1261063

Similar proteinsi

Entry informationi

Entry nameiOCR_BPT7
AccessioniPrimary (citable) accession number: P03775
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health