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Protein

Tail tubular protein gp12

Gene

12

Organism
Enterobacteria phage T7 (Bacteriophage T7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Structural component of the short non-contractile tail. The tail complex is involved in viral genome delivery. Forms the end of the tail, including the canonical tube, the nozzle, and the small extensions below the fibers. Once the tail tubular structure is formed, the interface between gp11 and gp12 generates the proper environment to interact with the six gp17 trimers.1 Publication

GO - Biological processi

Keywordsi

Molecular functionViral short tail ejection system
Biological processViral genome ejection through host cell envelope, Viral penetration into host cytoplasm, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Tail tubular protein gp12
Alternative name(s):
Gene product 12
Short name:
Gp12
Gene namesi
Ordered Locus Names:12
OrganismiEnterobacteria phage T7 (Bacteriophage T7)
Taxonomic identifieri10760 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000000840 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Viral tail protein, Viral tail tube protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001065261 – 794Tail tubular protein gp12Add BLAST794

Interactioni

Subunit structurei

Interacts with head-to-tail connector protein gp8, the tail component gp11, and the fiber protein gp17.1 Publication

Protein-protein interaction databases

MINTiMINT-1513641.

Family & Domainsi

Phylogenomic databases

OrthoDBiVOG0900003C.

Sequencei

Sequence statusi: Complete.

P03747-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALISQSIKN LKGGISQQPD ILRYPDQGSR QVNGWSSETE GLQKRPPLVF
60 70 80 90 100
LNTLGDNGAL GQAPYIHLIN RDEHEQYYAV FTGSGIRVFD LSGNEKQVRY
110 120 130 140 150
PNGSNYIKTA NPRNDLRMVT VADYTFIVNR NVVAQKNTKS VNLPNYNPNQ
160 170 180 190 200
DGLINVRGGQ YGRELIVHIN GKDVAKYKIP DGSQPEHVNN TDAQWLAEEL
210 220 230 240 250
AKQMRTNLSD WTVNVGQGFI HVTAPSGQQI DSFTTKDGYA DQLINPVTHY
260 270 280 290 300
AQSFSKLPPN APNGYMVKIV GDASKSADQY YVRYDAERKV WTETLGWNTE
310 320 330 340 350
DQVLWETMPH ALVRAADGNF DFKWLEWSPK SCGDVDTNPW PSFVGSSIND
360 370 380 390 400
VFFFRNRLGF LSGENIILSR TAKYFNFYPA SIANLSDDDP IDVAVSTNRI
410 420 430 440 450
AILKYAVPFS EELLIWSDEA QFVLTASGTL TSKSVELNLT TQFDVQDRAR
460 470 480 490 500
PFGIGRNVYF ASPRSSFTSI HRYYAVQDVS SVKNAEDITS HVPNYIPNGV
510 520 530 540 550
FSICGSGTEN FCSVLSHGDP SKIFMYKFLY LNEELRQQSW SHWDFGENVQ
560 570 580 590 600
VLACQSISSD MYVILRNEFN TFLARISFTK NAIDLQGEPY RAFMDMKIRY
610 620 630 640 650
TIPSGTYNDD TFTTSIHIPT IYGANFGRGK ITVLEPDGKI TVFEQPTAGW
660 670 680 690 700
NSDPWLRLSG NLEGRMVYIG FNINFVYEFS KFLIKQTADD GSTSTEDIGR
710 720 730 740 750
LQLRRAWVNY ENSGTFDIYV ENQSSNWKYT MAGARLGSNT LRAGRLNLGT
760 770 780 790
GQYRFPVVGN AKFNTVYILS DETTPLNIIG CGWEGNYLRR SSGI
Length:794
Mass (Da):89,396
Last modified:July 21, 1986 - v1
Checksum:iC55E87879B266F4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01146 Genomic DNA. Translation: CAA24430.1.
PIRiA04372. TLBPB7.
RefSeqiNP_042000.1. NC_001604.1.

Genome annotation databases

GeneIDi1261024.
KEGGivg:1261024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01146 Genomic DNA. Translation: CAA24430.1.
PIRiA04372. TLBPB7.
RefSeqiNP_042000.1. NC_001604.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1513641.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1261024.
KEGGivg:1261024.

Phylogenomic databases

OrthoDBiVOG0900003C.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiTUBE2_BPT7
AccessioniPrimary (citable) accession number: P03747
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 10, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.