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Protein

Portal protein

Gene

8

Organism
Enterobacteria phage T7 (Bacteriophage T7)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Forms the portal vertex of the capsid (PubMed:15784250, PubMed:23884409). This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.Curated2 Publications

GO - Biological processi

Keywordsi

Molecular functionViral short tail ejection system
Biological processViral capsid assembly, Viral genome ejection through host cell envelope, Viral genome packaging, Viral penetration into host cytoplasm, Virus entry into host cell, Virus exit from host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Portal proteinCurated
Alternative name(s):
Gene product 8Curated
Short name:
Gp8
Head-to-tail connector gp8Curated
Gene namesi
Ordered Locus Names:8
OrganismiEnterobacteria phage T7 (Bacteriophage T7)
Taxonomic identifieri10760 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000000840 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001065171 – 536Portal proteinAdd BLAST536

Proteomic databases

PRIDEiP03728.

Interactioni

Subunit structurei

Homododecamer. Interacts with gp10, gp11, gp12, and the large terminase subunit gp19.4 Publications

Protein-protein interaction databases

MINTiMINT-1513362.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J4Aelectron microscopy12.00A/B/C/D/E/F/G/H/I/J/K/L1-497[»]
SMRiP03728.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

OrthoDBiVOG0900008P.

Family and domain databases

InterProiView protein in InterPro
IPR020991. Connector_podovirus.
PfamiView protein in Pfam
PF12236. Head-tail_con. 1 hit.

Sequencei

Sequence statusi: Complete.

P03728-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKRTGLAE DGAKSVYERL KNDRAPYETR AQNCAQYTIP SLFPKDSDNA
60 70 80 90 100
STDYQTPWQA VGARGLNNLA SKLMLALFPM QTWMRLTISE YEAKQLLSDP
110 120 130 140 150
DGLAKVDEGL SMVERIIMNY IESNSYRVTL FEALKQLVVA GNVLLYLPEP
160 170 180 190 200
EGSNYNPMKL YRLSSYVVQR DAFGNVLQMV TRDQIAFGAL PEDIRKAVEG
210 220 230 240 250
QGGEKKADET IDVYTHIYLD EDSGEYLRYE EVEGMEVQGS DGTYPKEACP
260 270 280 290 300
YIPIRMVRLD GESYGRSYIE EYLGDLRSLE NLQEAIVKMS MISSKVIGLV
310 320 330 340 350
NPAGITQPRR LTKAQTGDFV TGRPEDISFL QLEKQADFTV AKAVSDAIEA
360 370 380 390 400
RLSFAFMLNS AVQRTGERVT AEEIRYVASE LEDTLGGVYS ILSQELQLPL
410 420 430 440 450
VRVLLKQLQA TQQIPELPKE AVEPTISTGL EAIGRGQDLD KLERCVTAWA
460 470 480 490 500
ALAPMRDDPD INLAMIKLRI ANAIGIDTSG ILLTEEQKQQ KMAQQSMQMG
510 520 530
MDNGAAALAQ GMAAQATASP EAMAAAADSV GLQPGI
Length:536
Mass (Da):59,120
Last modified:July 21, 1986 - v1
Checksum:iCDE87B92DC4A6C65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01146 Genomic DNA. Translation: CAA24425.1.
PIRiA04354. JQBPT7.
RefSeqiNP_041995.1. NC_001604.1.

Genome annotation databases

GeneIDi1261033.
KEGGivg:1261033.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPORTL_BPT7
AccessioniPrimary (citable) accession number: P03728
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 10, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families