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Protein

Portal protein

Gene

8

Organism
Enterobacteria phage T7 (Bacteriophage T7)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Forms the portal vertex of the capsid. This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.UniRule annotation2 Publications

GO - Biological processi

Keywordsi

Molecular functionViral short tail ejection system
Biological processViral capsid assembly, Viral genome ejection through host cell envelope, Viral genome packaging, Viral penetration into host cytoplasm, Viral release from host cell, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Portal proteinUniRule annotationCurated
Alternative name(s):
Gene product 8Curated
Short name:
Gp8
Head-to-tail connectorUniRule annotationCurated
Gene namesi
Ordered Locus Names:8
OrganismiEnterobacteria phage T7 (Bacteriophage T7)
Taxonomic identifieri10760 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000000840 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

  • viral portal complex Source: UniProtKB

Keywords - Cellular componenti

Capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001065171 – 536Portal proteinAdd BLAST536

Interactioni

Subunit structurei

Homododecamer. Interacts with major capsid protein. Interacts with the tail tube protein gp11. Interacts with the terminase large subunit. Interacts with the internal virion protein gp14.UniRule annotation4 Publications

Protein-protein interaction databases

MINTiP03728

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J4Aelectron microscopy12.00A/B/C/D/E/F/G/H/I/J/K/L1-497[»]
SMRiP03728
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the podoviridae portal protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG0900008P

Family and domain databases

HAMAPiMF_04120 PORTAL_PROTEIN_T7, 1 hit
InterProiView protein in InterPro
IPR020991 Connector_podovirus
IPR038995 Portal_prot_Caudovirale
PfamiView protein in Pfam
PF12236 Head-tail_con, 1 hit

Sequencei

Sequence statusi: Complete.

P03728-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKRTGLAE DGAKSVYERL KNDRAPYETR AQNCAQYTIP SLFPKDSDNA
60 70 80 90 100
STDYQTPWQA VGARGLNNLA SKLMLALFPM QTWMRLTISE YEAKQLLSDP
110 120 130 140 150
DGLAKVDEGL SMVERIIMNY IESNSYRVTL FEALKQLVVA GNVLLYLPEP
160 170 180 190 200
EGSNYNPMKL YRLSSYVVQR DAFGNVLQMV TRDQIAFGAL PEDIRKAVEG
210 220 230 240 250
QGGEKKADET IDVYTHIYLD EDSGEYLRYE EVEGMEVQGS DGTYPKEACP
260 270 280 290 300
YIPIRMVRLD GESYGRSYIE EYLGDLRSLE NLQEAIVKMS MISSKVIGLV
310 320 330 340 350
NPAGITQPRR LTKAQTGDFV TGRPEDISFL QLEKQADFTV AKAVSDAIEA
360 370 380 390 400
RLSFAFMLNS AVQRTGERVT AEEIRYVASE LEDTLGGVYS ILSQELQLPL
410 420 430 440 450
VRVLLKQLQA TQQIPELPKE AVEPTISTGL EAIGRGQDLD KLERCVTAWA
460 470 480 490 500
ALAPMRDDPD INLAMIKLRI ANAIGIDTSG ILLTEEQKQQ KMAQQSMQMG
510 520 530
MDNGAAALAQ GMAAQATASP EAMAAAADSV GLQPGI
Length:536
Mass (Da):59,120
Last modified:July 21, 1986 - v1
Checksum:iCDE87B92DC4A6C65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01146 Genomic DNA Translation: CAA24425.1
PIRiA04354 JQBPT7
RefSeqiNP_041995.1, NC_001604.1

Genome annotation databases

GeneIDi1261033
KEGGivg:1261033

Similar proteinsi

Entry informationi

Entry nameiPORTL_BPT7
AccessioniPrimary (citable) accession number: P03728
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 23, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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