Reviewed, UniProtKB/Swiss-Prot P03726 (VIVD_BPT7)

Names and origin

Protein names

Recommended name:
    Internal virion protein D

Gene names

Name:

16

Organism

Enterobacteria phage T7 (Bacteriophage T7)

Taxonomic identifier

10760 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Caudovirales › Podoviridae › Autographivirinae › T7-like viruses

Virus host

Escherichia coli [TaxID: 562]

Protein attributes

Sequence length	1318 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	May be involved in the lysis of the bacterial cell wall during the release of the phage progeny.
Sequence similarities	Belongs to the transglycosylase slt family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Molecular function	Lyase
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lyase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1318	1318	Internal virion protein D		PRO_0000196560
Regions
	Region	24 – 111	88	Slt-type domain
Sites
	Active site	37	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P03726-1 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 51A0AAA920CBF210	FASTA	1,318	143,838
	10 20 30 40 50 60 MDKYDKNVPS DYDGLFQKAA DANGVSYDLL RKVAWTESRF VPTAKSKTGP LGMMQFTKAT 70 80 90 100 110 120 AKALGLRVTD GPDDDRLNPE LAINAAAKQL AGLVGKFDGD ELKAALAYNQ GEGRLGNPQL 130 140 150 160 170 180 EAYSKGDFAS ISEEGRNYMR NLLDVAKSPM AGQLETFGGI TPKGKGIPAE VGLAGIGHKQ 190 200 210 220 230 240 KVTQELPEST SFDVKGIEQE ATAKPFAKDF WETHGETLDE YNSRSTFFGF KNAAEAELSN 250 260 270 280 290 300 SVAGMAFRAG RLDNGFDVFK DTITPTRWNS HIWTPEELEK IRTEVKNPAY INVVTGGSPE 310 320 330 340 350 360 NLDDLIKLAN ENFENDSRAA EAGLGAKLSA GIIGAGVDPL SYVPMVGVTG KGFKLINKAL 370 380 390 400 410 420 VVGAESAALN VASEGLRTSV AGGDADYAGA ALGGFVFGAG MSAISDAVAA GLKRSKPEAE 430 440 450 460 470 480 FDNEFIGPMM RLEARETARN ANSADLSRMN TENMKFEGEH NGVPYEDLPT ERGAVVLHDG 490 500 510 520 530 540 SVLSASNPIN PKTLKEFSEV DPEKAARGIK LAGFTEIGLK TLGSDDADIR RVAIDLVRSP 550 560 570 580 590 600 TGMQSGASGK FGATASDIHE RLHGTDQRTY NDLYKAMSDA MKDPEFSTGG AKMSREETRY 610 620 630 640 650 660 TIYRRAALAI ERPELQKALT PSERIVMDII KRHFDTKREL MENPAIFGNT KAVSIFPESR 670 680 690 700 710 720 HKGTYVPHVY DRHAKALMIQ RYGAEGLQEG IARSWMNSYV SRPEVKARVD EMLKELHGVK 730 740 750 760 770 780 EVTPEMVEKY AMDKAYGISH SDQFTNSSII EENIEGLVGI ENNSFLEARN LFDSDLSITM 790 800 810 820 830 840 PDGQQFSVND LRDFDMFRIM PAYDRRVNGD IAIMGSTGKT TKELKDEILA LKAKAEGDGK 850 860 870 880 890 900 KTGEVHALMD TVKILTGRAR RNQDTVWETS LRAINDLGFF AKNAYMGAQN ITEIAGMIVT 910 920 930 940 950 960 GNVRALGHGI PILRDTLYKS KPVSAKELKE LHASLFGKEV DQLIRPKRAD IVQRLREATD 970 980 990 1000 1010 1020 TGPAVANIVG TLKYSTQELA ARSPWTKLLN GTTNYLLDAA RQGMLGDVIS ATLTGKTTRW 1030 1040 1050 1060 1070 1080 EKEGFLRGAS VTPEQMAGIK SLIKEHMVRG EDGKFTVKDK QAFSMDPRAM DLWRLADKVA 1090 1100 1110 1120 1130 1140 DEAMLRPHKV SLQDSHAFGA LGKMVMQFKS FTIKSLNSKF LRTFYDGYKN NRAIDAALSI 1150 1160 1170 1180 1190 1200 ITSMGLAGGF YAMAAHVKAY ALPKEKRKEY LERALDPTMI AHAALSRSSQ LGAPLAMVDL 1210 1220 1230 1240 1250 1260 VGGVLGFESS KMARSTILPK DTVKERDPNK PYTSREVMGA MGSNLLEQMP SAGFVANVGA 1270 1280 1290 1300 1310 TLMNAAGVVN SPNKATEQDF MTGLMNSTKE LVPNDPLTQQ LVLKIYEANG VNLRERRK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of bacteriophage T7 DNA and the locations of T7 genetic elements." Dunn J.J., Studier F.W. J. Mol. Biol. 166:477-535(1983) [PubMed: 6864790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"A conserved domain in putative bacterial and bacteriophage transglycosylases." Koonin E.V., Rudd K.E. Trends Biochem. Sci. 19:106-107(1994) [PubMed: 8203016] [Abstract] Cited for: SIMILARITY TO SLT.

Cross-references

Sequence databases
EMBLGenBankDDBJ	V01146 Genomic DNA. Translation: CAA24434.1.
PIR	HIBPD7. A04352.
RefSeq	NP_042004.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH23. Glycoside Hydrolase Family 23.
TCDB	3.A.17.1.1. phage T7 injectisome family.
Genome annotation databases
GeneID	1261031.
GenomeReviews	Gene locus 16 in contig V01146_GR.
Family and domain databases
InterPro	IPR008258. Lytic_TGlycosylase-like_cat. IPR000189. Transglyc_AS. [Graphical view]
Pfam	PF01464. SLT. 1 hit. [Graphical view]
PROSITE	PS00922. TRANSGLYCOSYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VIVD_BPT7

Accession

Primary (citable) accession number: P03726

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	April 14, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Virus (Virus annotation project)