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P03699 (VXIS_LAMBD) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Excisionase
Gene names
Name:xis
OrganismEnterobacteria phage lambda (Bacteriophage lambda)
Taxonomic identifier10710 [NCBI]
Taxonomic lineageViruses › dsDNA viruses, no RNA stage › Caudovirales › Siphoviridae › Lambda-like viruses
Virus hostEscherichia coli [TaxID: 562]

Protein attributes

Sequence length72 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination at the att site.

Ontologies

Keywords
   Biological processDNA recombination
   LigandDNA-binding
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processDNA recombination

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7272Excisionase
PRO_0000077714

Secondary structure

1 ............. 72
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P03699 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 0E6A4843502200AA

FASTA728,605
        10         20         30         40         50         60 
MYLTLQEWNA RQRRPRSLET VRRWVRECRI FPPPVKDGRE YLFHESAVKV DLNRPVTGGL 

        70 
LKRIRNGKKA KS

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence of bacteriophage lambda DNA."
Sanger F., Coulson A.R., Hong G.F., Hill D.F., Petersen G.B.
J. Mol. Biol. 162:729-773(1982) [PubMed: 6221115] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"DNA sequence of the int-xis-Pi region of the bacteriophage lambda; overlap of the int and xis genes."
Davies R.W.
Nucleic Acids Res. 8:1765-1782(1980) [PubMed: 6253947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"Site-specific recombination functions of bacteriophage lambda: DNA sequence of regulatory regions and overlapping structural genes for Int and Xis."
Hoess R.H., Foeller C., Bidwell K., Landy A.
Proc. Natl. Acad. Sci. U.S.A. 77:2482-2486(1980) [PubMed: 6446713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		J02459 Genomic DNA. Translation: AAA96563.1.
PIRRSBPXL. C94164.
RefSeqNP_040610.1. NC_001416.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1LX8NMR-A1-55[»]
1RH6X-ray1.70A/B1-55[»]
2IEFX-ray2.60A/B/C1-55[»]
2OG0X-ray1.90A/B1-52[»]
ProteinModelPortalP03699.
SMRP03699. Positions 1-72.
ModBaseSearch...

Protein-protein interaction databases

IntActP03699. 2 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2703504.
GenomeReviewsGene locus lambdap35 in contig J02459_GR.

Phylogenomic databases

ProtClustDBCLSP987264.

Family and domain databases

InterProIPR009061. DNA-bd_dom_put.
IPR012884. Excisionase-like.
[Graphical view]
Gene3DG3DSA:1.10.1660.20. Excisionase-like. 1 hit.
PfamPF07825. Exc. 1 hit.
[Graphical view]
SUPFAMSSF46955. Putativ_DNA_bind. 1 hit.
ProtoNetSearch...

Entry information

Entry nameVXIS_LAMBD
AccessionPrimary (citable) accession number: P03699
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

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