Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Virion export protein

Gene

IV

Organism
Enterobacteria phage f1 (Bacteriophage f1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Acts in the assembly and extrusion of the bacteriophage by forming a channel across the host outer membrane. This channel is just large enough to allow a newly synthesized phage particle to pass through. Extrusion is a process of concomitant assembly and secretion and takes place at specific assembly sites where host inner and outer membranes are in close contacts.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processViral extrusion, Viral release from host cell

Protein family/group databases

TCDBi1.B.22.5.1 the outer bacterial membrane secretin (secretin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Virion export protein
Alternative name(s):
Gene 4 protein
Short name:
G4P
Gene namesi
Name:IV
OrganismiEnterobacteria phage f1 (Bacteriophage f1)
Taxonomic identifieri10863 [NCBI]
Taxonomic lineageiVirusesssDNA virusesInoviridaeInovirus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000002557 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei317 – 337HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000020944822 – 426Virion export proteinAdd BLAST405

Proteomic databases

PRIDEiP03666

Interactioni

Subunit structurei

Homomultimer. The channel is composed of 14 G4P subunits that confer a barrel-like structure. Interacts with G1P; this interaction results in a complex that spans the inner an outer host membranes (By similarity).By similarity

Structurei

3D structure databases

SMRiP03666
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inovirus G4P protein family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090000G8

Family and domain databases

Gene3Di3.30.1370.120, 1 hit
InterProiView protein in InterPro
IPR001775 GspD/PilQ
IPR038591 NolW-like_sf
IPR004846 T2SS/T3SS
IPR004845 T2SS_GspD_CS
PfamiView protein in Pfam
PF00263 Secretin, 1 hit
PRINTSiPR00811 BCTERIALGSPD
PROSITEiView protein in PROSITE
PS00875 T2SP_D, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P03666-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLNVINFV FLMFVSSSSF AQVIEMNNSS LRDFVTWYSK QTGESVIVSP
60 70 80 90 100
DVKGTVTVYS SDVKPENLRD FFISVLRANN FDMVGSIPSI IQKYNPNNQD
110 120 130 140 150
YIDELPSSDN QEYDDNSAPS GGFFVPQNDN VTQTFKINNV RAKDLIRVVE
160 170 180 190 200
LFVKSNTSKS SNVLSVDGSN LLVVSAPKDI LDNLPQFLST VDLPTDQILI
210 220 230 240 250
EGLIFEVQQG DALDFSFAAG SQRGTVAGGV NTDRLTSVLS SAGGSFGIFN
260 270 280 290 300
GDVLGLSVRA LKTNSHSKIL SVPRILTLSG QKGSISVGQN VPFITGRVTG
310 320 330 340 350
ESANVNNPFQ TVERQNVGIS MSVFPVAMAG GNIVLDITSK ADSLSSSTQA
360 370 380 390 400
SDVITNQRSI ATTVNLRDGQ TLLLGGLTDY KNTSQDSGVP FLSKIPLIGL
410 420
LFSSRSDSNE ESTLYVLVKA TIVRAL
Length:426
Mass (Da):45,842
Last modified:July 21, 1986 - v1
Checksum:i27593CC35BAE610B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti30S → P in AAA32218 (PubMed:6292494).Curated1
Sequence conflicti70D → N in AAA32218 (PubMed:6292494).Curated1
Sequence conflicti87I → N in AAA32218 (PubMed:6292494).Curated1
Sequence conflicti166V → I in AAA32218 (PubMed:6292494).Curated1
Sequence conflicti312V → I in AAA32218 (PubMed:6292494).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00606 Genomic DNA Translation: CAA23875.1
J02448 Genomic DNA Translation: AAA32218.1
M10641 Genomic DNA Translation: AAA32222.1
M38348 Genomic DNA Translation: AAA32221.1 Sequence problems.
PIRiC04268 Z4BPF1

Similar proteinsi

Entry informationi

Entry nameiG4P_BPF1
AccessioniPrimary (citable) accession number: P03666
Secondary accession number(s): Q96223
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: March 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health