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Protein

Major spike protein G

Gene

G

Organism
Enterobacteria phage phiX174 (Isolate Sanger) (Bacteriophage phi-X174)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Attaches the circulating virion to the bacterial lipopolysaccharides which serve as receptor for the virus. Determines the phage host-range. Probably triggers with protein H the injection of the phage DNA into the host cytoplasm upon conformational changes induced by the interaction with host lipopolysaccharides.2 Publications

GO - Biological processi

Keywordsi

Biological processHost-virus interaction, Viral attachment to host cell, Viral genome ejection through host cell envelope, Viral penetration into host cytoplasm, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Major spike protein G
Alternative name(s):
G protein
GPG
Gene namesi
Name:G
OrganismiEnterobacteria phage phiX174 (Isolate Sanger) (Bacteriophage phi-X174)
Taxonomic identifieri1217068 [NCBI]
Taxonomic lineageiVirusesssDNA virusesMicroviridaeBullavirinaePhix174microvirus
Virus hostiEscherichia coli C [TaxID: 498388]
Proteomesi
  • UP000005893 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001648951 – 175Major spike protein GAdd BLAST175

Interactioni

Subunit structurei

Pentamerizes and interacts with H protein, F and B pentamers to form 12S pre-assembly complex. Joining of twelve 12S complex form the procapsid.

Protein-protein interaction databases

DIPiDIP-6199N.

Structurei

Secondary structure

1175
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi13 – 17Combined sources5
Beta strandi26 – 28Combined sources3
Beta strandi30 – 33Combined sources4
Beta strandi36 – 49Combined sources14
Beta strandi51 – 61Combined sources11
Beta strandi69 – 83Combined sources15
Beta strandi88 – 98Combined sources11
Beta strandi108 – 110Combined sources3
Beta strandi115 – 117Combined sources3
Beta strandi120 – 130Combined sources11
Beta strandi134 – 137Combined sources4
Beta strandi139 – 150Combined sources12
Beta strandi152 – 163Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AL0X-ray3.50G1-175[»]
1CD3X-ray3.50G1-175[»]
1PHXmodel-21-175[»]
2BPAX-ray3.0021-175[»]
ProteinModelPortaliP03643.
SMRiP03643.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP03643.

Family & Domainsi

Sequence similaritiesi

Belongs to the microvirus G protein family.Curated

Phylogenomic databases

OrthoDBiVOG090000UM.

Family and domain databases

InterProiView protein in InterPro
IPR016184. Capsid/spike_ssDNA_virus.
IPR003515. Spike_G.
PfamiView protein in Pfam
PF02306. Phage_G. 1 hit.
PIRSFiPIRSF004159. Spike_G. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD013365. Spike_G. 1 hit.
SUPFAMiSSF88645. SSF88645. 1 hit.

Sequencei

Sequence statusi: Complete.

P03643-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFQTFISRHN SNFFSDKLVL TSVTPASSAP VLQTPKATSS TLYFDSLTVN
60 70 80 90 100
AGNGGFLHCI QMDTSVNAAN QVVSVGADIA FDADPKFFAC LVRFESSSVP
110 120 130 140 150
TTLPTAYDVY PLNGRHDGGY YTVKDCVTID VLPRTPGNNV YVGFMVWSNF
160 170
TATKCRGLVS LNQVIKEIIC LQPLK
Length:175
Mass (Da):19,047
Last modified:July 21, 1986 - v1
Checksum:iAA2418CD82666A7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02482 Genomic DNA. Translation: AAA32579.1.
PIRiC93185. ZGBPF4.

Similar proteinsi

Entry informationi

Entry nameiG_BPPHS
AccessioniPrimary (citable) accession number: P03643
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 10, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families