P03608 (COAT_TYMV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Coat protein Alternative name(s): Virion protein
Organism	Turnip yellow mosaic virus [Reference proteome]
Taxonomic identifier	12154 [NCBI]
Taxonomic lineage	Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Tymovirales › Tymoviridae › Tymovirus
Virus host	Brassica [TaxID: 3705] Cardamine lilacina [TaxID: 82359]

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	The virus coat is composed of 180 copies of the coat protein arranged in a icosahedral shell.
Subcellular location	Virion Potential.
Sequence similarities	Belongs to the tymoviruses coat protein family.

Ontologies

Keywords
Cellular component	Virion
Molecular function	Capsid protein T=3 icosahedral capsid protein
PTM	Acetylation
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Cellular_component	T=3 icosahedral viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 189

189

Coat protein

PRO_0000222931

Amino acid modifications

Modified residue

1

1

N-acetylmethionine; by host

Experimental info

Sequence conflict

86

1

T → A in CAA30323. Ref.6

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

189

Helix Strand Turn

Details...

Beta strand

30 – 45

16

Beta strand

47 – 52

6

Helix

53 – 55

3

Helix

57 – 63

7

Beta strand

66 – 80

15

Helix

83 – 86

4

Beta strand

89 – 97

9

Helix

104 – 109

6

Beta strand

110 – 112

3

Beta strand

114 – 118

5

Beta strand

129 – 131

3

Helix

134 – 136

3

Beta strand

140 – 142

3

Beta strand

151 – 158

8

Beta strand

168 – 182

15

Sequences

	Sequence		Length	Mass (Da)
	P03608 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 082F7EF9307554BC	FASTA	189	20,088
	10 20 30 40 50 60 MEIDKELAPQ DRTVTVATVL PAVPGPSPLT IKQPFQSEVL FAGTKDAEAS LTIANIDSVS 70 80 90 100 110 120 TLTTFYRHAS LESLWVTIHP TLQAPTFPTT VGVCWVPANS PVTPAQITKT YGGQIFCIGG 130 140 150 160 170 180 AINTLSPLIV KCPLEMMNPR VKDSIQYLDS PKLLISITAQ PTAPPASTCI ITVSGTLSMH SPLITDTST

References

[1]	"Study of the primary structure of the protein from turnip yellow mosaic virus. III. Sequence of the chymotryptic peptides of the aminoethylated protein and of order of the tryptic peptides." Stehelin D., Peter R., Duranton H. Biochim. Biophys. Acta 317:253-265(1973) Cited for: PROTEIN SEQUENCE.
[2]	"Nucleotide sequence of turnip yellow mosaic virus coat protein mRNA." Guilley H., Briand J.-P. Cell 15:113-122(1978) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]	"Nucleotide sequence (n=159) of the amino-acid-accepting 3'-OH extremity of turnip-yellow-mosaic-virus RNA and the last portion of its coat-protein cistron." Briand J.-P., Jonard G., Guilley H., Richards K., Hirth L. Eur. J. Biochem. 72:453-463(1977) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[4]	"Studies on the sequence of the 3'-terminal region of turnip-yellow-mosaic-virus RNA." Silberklang M., Prochiantz A., Haenni A.L., RajBhandary U.L. Eur. J. Biochem. 72:465-478(1977) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[5]	"Analysis of the in vitro coding properties of the 3' region of turnip yellow mosaic virus genomic RNA." Morch M.D., Drugeon G., Benicourt C. Virology 119:193-198(1982) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[6]	"Overlapping open reading frames revealed by complete nucleotide sequencing of turnip yellow mosaic virus genomic RNA." Morch M.D., Boyer J.C., Haenni A.L. Nucleic Acids Res. 16:6157-6173(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[7]	"Genomic RNA sequence of turnip yellow mosaic virus isolate TYMC, a cDNA-based clone with verified infectivity." Dreher T.W., Bransom K.L. Plant Mol. Biol. 18:403-406(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: Isolate TYMC.
[8]	"Crystal structure of turnip yellow mosaic virus." Canady M.A., Larson S.B., Day J., McPherson A. Nat. Struct. Biol. 3:771-781(1996) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS).
+	Additional computationally mapped references.

Web resources

Virus Particle ExploreR db

Icosahedral capsid structure

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

V01418 mRNA. Translation: CAA24690.1.
K00602 Genomic RNA. Translation: AAA46590.1.
X07441 Genomic RNA. Translation: CAA30323.1.
X16378 Genomic RNA. Translation: CAA34416.1.
M54918 Genomic RNA. Translation: AAA46604.1.

PIR

VCTY. S19153.

RefSeq

NP_663298.1. NC_004063.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1AUY	X-ray	3.00	A/B/C	1-189	[»]
1W39	X-ray	3.75	A/B/C	1-189	[»]

ProteinModelPortal

P03608.

SMR

P03608. Positions 1-189.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

951157.

Family and domain databases

InterPro

IPR000574. Tymo_coat.
[Graphical view]

Pfam

PF00983. Tymo_coat. 1 hit.
[Graphical view]

ProDom

PD003886. Tymo_coat. 1 hit.
[Graphical view] [Entries sharing at least one domain]

ProtoNet

Search...

Other

EvolutionaryTrace

P03608.

Entry information

Entry name

COAT_TYMV

Accession

Primary (citable) accession number: P03608

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	April 3, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program