P03579 (CAPSD_TMGMV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Capsid protein

Alternative name(s):
Coat protein

Gene names

Name:

CP

Organism

Tobacco mild green mosaic virus (TMGMV) (TMV strain U2) [Complete proteome]

Taxonomic identifier

12241 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Virgaviridae › Tobamovirus

Virus host

Capsicum annuum (Bell pepper) [TaxID: 4072]
Eryngium planum [TaxID: 43071]
Nicotiana glauca (Glaucous tobacco) (Tree tobacco) [TaxID: 4090]
Nicotiana tabacum (Common tobacco) [TaxID: 4097]

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
Subcellular location	Virion Potential.
Sequence similarities	Belongs to the virgaviridae capsid protein family.

Ontologies

Keywords
Cellular component	Virion
Molecular function	Capsid protein
Technical term	3D-structure Complete proteome Direct protein sequencing
Gene Ontology (GO)
Cellular_component	viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

1

1

Removed; by host Ref.4

Chain

2 – 159

158

Capsid protein

PRO_0000144945

Experimental info

Sequence conflict

23

1

Q → E AA sequence Ref.4

Sequence conflict

56 – 58

3

VPS → SPV AA sequence Ref.4

Sequence conflict

101 – 112

12

PAPNT…IVNAT → ABPTTAVPIBTZ AA sequence Ref.5

Secondary structure

1

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159

Helix Strand Turn

Details...

Turn

8 – 10

3

Helix

11 – 14

4

Helix

22 – 24

3

Helix

25 – 31

7

Helix

39 – 52

14

Beta strand

59 – 61

3

Beta strand

69 – 74

6

Helix

77 – 87

11

Turn

98 – 101

4

Beta strand

106 – 110

5

Turn

112 – 116

5

Helix

117 – 131

15

Beta strand

133 – 135

3

Helix

142 – 145

4

Sequences

	Sequence		Length	Mass (Da)
	P03579 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 7F0169830984069F	FASTA	159	17,590
	10 20 30 40 50 60 MPYTINSPSQ FVYLSSAYAD PVQLINLCTN ALGNQFQTQQ ARTTVQQQFA DAWKPVPSMT 70 80 90 100 110 120 VRFPASDFYV YRYNSTLDPL ITALLNSFDT RNRIIEVDNQ PAPNTTEIVN ATQRVDDATV 130 140 150 AIRASINNLA NELVRGTGMF NQAGFETASG LVWTTTPAT

References

[1]	"The complete nucleotide sequence of the genomic RNA of the tobamovirus tobacco mild green mosaic virus." Solis I., Garcia-Arenal F. Virology 177:553-558(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"Transfer of the movement protein gene between two tobamoviruses: influence on local lesion development." Nejidat A., Cellier F., Holt C.A., Gafny R., Eggenberger A.L., Beachy R.N. Virology 180:318-326(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: ATCC PV-228.
[3]	"Heterogeneity in the 3'-terminal untranslated region of tobacco mild green mosaic tobamoviruses from Nicotiana glauca resulting in variants with three or six pseudoknots." Bodaghi S., Ngon A Yassi M., Dodds J.A. J. Gen. Virol. 81:577-586(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: TMGMVCPR-22.
[4]	"Primary protein structure of strains of tobacco mosaic virus. IV. Amino acid sequences (1 to 61 and 135 to 158) of proteins of tobacco mosaic virus strain U2." Wittmann H.G. Z. Naturforsch. B 20:1213-1223(1965) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-62 AND 136-159.
[5]	"Amino acid sequence and physico-chemical behavior of coat proteins of wild strain tobacco mosaic virus. I. Analysis of primary structure (pos. 62-134) of coat proteins of wild strain U2." Rentschler L. Mol. Gen. Genet. 100:84-95(1967) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 63-135.
[6]	"Structure of the U2 strain of tobacco mosaic virus refined at 3.5-A resolution using X-ray fiber diffraction." Pattanayek R., Stubbs G. J. Mol. Biol. 228:516-528(1992) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

M34077 Genomic RNA. Translation: AAA47937.1.
M34236 Genomic RNA. Translation: AAA47939.1.
AF132907 Genomic RNA. Translation: AAD41791.1.

PIR

VCTMUT. C35520.

RefSeq

NP_062916.1. NC_001556.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VTM	fiber diffraction	3.50	P	2-159	[»]

ProteinModelPortal

P03579.

SMR

P03579. Positions 2-159.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1494073.

Family and domain databases

InterPro

IPR001337. TMV-like_coat.
[Graphical view]

Pfam

PF00721. TMV_coat. 1 hit.
[Graphical view]

SUPFAM

SSF47195. TMV_coat. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

P03579.

Entry information

Entry name

CAPSD_TMGMV

Accession

Primary (citable) accession number: P03579

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 72 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program