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P03513 (NCAP_BUNSH) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name=Protein N
Gene names
Name:N
OrganismBunyavirus snowshoe hare
Taxonomic identifier11580 [NCBI]
Taxonomic lineageVirusesssRNA negative-strand virusesBunyaviridaeOrthobunyavirus
Virus hostAedes [TaxID: 7158]
Bos taurus (Bovine) [TaxID: 9913]
Canis familiaris (Dog) (Canis lupus familiaris) [TaxID: 9615]
Culex [TaxID: 7174]
Culiseta [TaxID: 174825]
Equus caballus (Horse) [TaxID: 9796]
Gallus gallus (Chicken) [TaxID: 9031]
Homo sapiens (Human) [TaxID: 9606]
Lepus americanus (Snowshoe hare) [TaxID: 48086]

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication. Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation By similarity.

Subunit structure

Homomultimerizes to form the nucleocapsid By similarity. Binds to viral genomic RNA By similarity. Interacts with host PABP1 By similarity.

Subcellular location

Virion. Note: Internal protein of virus particle.

Sequence similarities

Belongs to the orthobunyavirus nucleocapsid protein family.

Alternative products

This entry describes 2 isoforms produced by alternative initiation. [Align] [Select]
Isoform N (identifier: P03513-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform NSS (identifier: P03514-1)

The sequence of this isoform can be found in the external entry P03514.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by alternative initiation in the N gene, but encoded on another frame.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 235235Nucleoprotein
PRO_0000221991

Sequences

Sequence LengthMass (Da)Tools
Isoform N [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 687ED1D57AC097F8

FASTA23526,771
        10         20         30         40         50         60 
MSDLVFYDVA STGANGFDPD AGYMAFCVKY AESVNLAAVR IFFLNAAKAK AALSRKPERK 

        70         80         90        100        110        120 
ANPKFGEWQV EVVNNHFPGN RNNPINSDDL TIHRLSGYLA RWVLEQYKEN EDESRRELIK 

       130        140        150        160        170        180 
TTIINPIAES NGVRWDSGAE IYLSFFPGTE MFLETFKFYP LTIGIYRVKQ GMMDPQYLKK 

       190        200        210        220        230 
ALRQRYGSLT ADKWMSQKVT AIAKSLKEVE QLKWGRGGLS DTARSFLQKF GIRLP 

« Hide

Isoform NSS [UniParc].

See P03514.

References

[1]"The complete sequence and coding content of snowshoe hare bunyavirus small (S) viral RNA species."
Bishop D.H.L., Gould K.G., Akashi H., Clerx-Van Haaster C.M.
Nucleic Acids Res. 10:3703-3713(1982) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
J02390 Genomic RNA. No translation available.
PIRVHVUNH. A04103.

3D structure databases

ProteinModelPortalP03513.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR001784. Bunya_nucleocap.
[Graphical view]
PfamPF00952. Bunya_nucleocap. 1 hit.
[Graphical view]
PIRSFPIRSF003947. N_OrthobunV. 1 hit.
ProDomPD001909. Bunya_nucleocap. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameNCAP_BUNSH
AccessionPrimary (citable) accession number: P03513
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: July 9, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families