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Reviewed, UniProtKB/Swiss-Prot P03276 (PEN3_ADE02)

Last modified July 28, 2009. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Penton protein
Alternative name(s):
    Virion component III
    Penton base protein
    pIII
Gene names
Name: PIII
OrganismHuman adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
Taxonomic identifier10515 [NCBI]
Taxonomic lineageViruses › dsDNA viruses, no RNA stage › Adenoviridae › Mastadenovirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

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Protein attributes

Sequence length571 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subunit structure

Interacts with host WWP1 and WWP2. Ref.3

Sequence similarities

Belongs to the adenoviridae pIII family.

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Ontologies

Keywords
   Biological processHost-virus interaction
   Developmental stageLate protein
   Technical term3D-structure
Gene Ontology (GO)
   Biological processinterspecies interaction between organisms

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionstructural molecule activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 571571Penton protein
PRO_0000221872

Secondary structure

1 ........................................................................................ 571
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
P03276-1 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: E9807342982B1BC7

FASTA57163,255
        10         20         30         40         50         60 
MQRAAMYEEG PPPSYESVVS AAPVAAALGS PFDAPLDPPF VPPRYLRPTG GRNSIRYSEL 

        70         80         90        100        110        120 
APLFDTTRVY LVDNKSTDVA SLNYQNDHSN FLTTVIQNND YSPGEASTQT INLDDRSHWG 

       130        140        150        160        170        180 
GDLKTILHTN MPNVNEFMFT NKFKARVMVS RSLTKDKQVE LKYEWVEFTL PEGNYSETMT 

       190        200        210        220        230        240 
IDLMNNAIVE HYLKVGRQNG VLESDIGVKF DTRNFRLGFD PVTGLVMPGV YTNEAFHPDI 

       250        260        270        280        290        300 
ILLPGCGVDF THSRLSNLLG IRKRQPFQEG FRITYDDLEG GNIPALLDVD AYQASLKDDT 

       310        320        330        340        350        360 
EQGGDGAGGG NNSGSGAEEN SNAAAAAMQP VEDMNDHAIR GDTFATRAEE KRAEAEAAAE 

       370        380        390        400        410        420 
AAAPAAQPEV EKPQKKPVIK PLTEDSKKRS YNLISNDSTF TQYRSWYLAY NYGDPQTGIR 

       430        440        450        460        470        480 
SWTLLCTPDV TCGSEQVYWS LPDMMQDPVT FRSTSQISNF PVVGAELLPV HSKSFYNDQA 

       490        500        510        520        530        540 
VYSQLIRQFT SLTHVFNRFP ENQILARPPA PTITTVSENV PALTDHGTLP LRNSIGGVQR 

       550        560        570 
VTITDARRRT CPYVYKALGI VSPRVLSSRT F

« Hide

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References

[1]"DNA sequences from the adenovirus 2 genome."
Roberts R.J., O'Neill K.E., Yen C.E.
J. Biol. Chem. 259:13968-13975(1984) [PubMed: 6334081] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Genes encoding the core proteins of adenovirus type 2."
Alestroem P., Akusjaervi G., Lager M., Yeh-kai L., Pettersson U.
J. Biol. Chem. 259:13980-13985(1984) [PubMed: 6094534] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 295-571.
[3]"Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases."
Galinier R., Gout E., Lortat-Jacob H., Wood J., Chroboczek J.
Biochemistry 41:14299-14305(2002) [PubMed: 12450395] [Abstract]
Cited for: INTERACTION WITH WWP1 AND WWP2.
+Additional computationally mapped references.

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Web resources

Virus Particle ExploreR db

Icosahedral capsid structure

Virus Particle ExploreR db

Icosahedral capsid structure in complex with an ad2 N-terminal fiber peptide

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		J01917 Genomic DNA. Translation: AAA92211.1.
PIRXZAD32. A03847.
RefSeqAP_000170.1.
NP_040521.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1X9PX-ray3.30A49-571[»]
1X9TX-ray3.50A49-571[»]
2BLDelectron microscopy10.00A/B/C/D/E49-571[»]
2C6SX-ray3.60A/B/C/D/E/F/G/H/I/J/K/L/M/N/O49-571[»]
2C9Felectron microscopy16.50A/B/C/D/E49-571[»]
2C9Gelectron microscopy9.30A/B/C/D/E49-571[»]
ModBaseSearch...

Genome annotation databases

GeneID2652996.

Family and domain databases

InterProIPR002605. Adeno_Penton_B.
[Graphical view]
PfamPF01686. Adeno_Penton_B. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry namePEN3_ADE02
AccessionPrimary (citable) accession number: P03276
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: July 28, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectVirus (Virus annotation project)

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Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents