##gff-version 3
P03255	UniProtKB	Chain	1	289	.	.	.	ID=PRO_0000221694;Note=Early E1A protein	
P03255	UniProtKB	Zinc finger	154	174	.	.	.	Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:1835093,ECO:0000269|PubMed:8146144;Dbxref=PMID:1835093,PMID:8146144	
P03255	UniProtKB	Region	41	49	.	.	.	Note=Interaction with RB1 in competition with E2F1;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P03255	UniProtKB	Region	76	140	.	.	.	Note=Interaction with UBE2I	
P03255	UniProtKB	Region	82	107	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P03255	UniProtKB	Region	186	240	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P03255	UniProtKB	Motif	113	117	.	.	.	Note=PXLXP motif%2C interaction with host ZMYND11	
P03255	UniProtKB	Motif	122	126	.	.	.	Note=LXCXE motif%2C interaction with host RB1 and TMEM173/STING;Ontology_term=ECO:0000255,ECO:0000269;evidence=ECO:0000255,ECO:0000269|PubMed:26405230;Dbxref=PMID:26405230	
P03255	UniProtKB	Motif	258	289	.	.	.	Note=Bipartite nuclear localization signal;Ontology_term=ECO:0000255,ECO:0000269;evidence=ECO:0000255,ECO:0000269|PubMed:25194920;Dbxref=PMID:25194920	
P03255	UniProtKB	Motif	279	283	.	.	.	Note=PXDLS motif%2C CTBP-binding;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7479821;Dbxref=PMID:7479821	
P03255	UniProtKB	Compositional bias	220	238	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P03255	UniProtKB	Modified residue	89	89	.	.	.	Note=Phosphoserine%3B by host;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:2966155;Dbxref=PMID:2966155	
P03255	UniProtKB	Modified residue	219	219	.	.	.	Note=Phosphoserine%3B by host;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:2966155;Dbxref=PMID:2966155	
P03255	UniProtKB	Modified residue	231	231	.	.	.	Note=Phosphoserine%3B by host;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:2966155;Dbxref=PMID:2966155	
P03255	UniProtKB	Alternative sequence	29	55	.	.	.	ID=VSP_028918;Note=In isoform early E1A 6 kDa protein. ADNLPPPSHFEPPTLHELYDLDVTAPE->CLNLSLSPSQNRSLQDLPAVLKWRLLS;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P03255	UniProtKB	Alternative sequence	56	289	.	.	.	ID=VSP_028919;Note=In isoform early E1A 6 kDa protein. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P03255	UniProtKB	Alternative sequence	140	185	.	.	.	ID=VSP_000198;Note=In isoform early E1A 26 kDa protein. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P03255	UniProtKB	Mutagenesis	115	115	.	.	.	Note=Complete loss of interaction with host ZMYND11. L->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11733528;Dbxref=PMID:11733528	
P03255	UniProtKB	Mutagenesis	122	126	.	.	.	Note=Abolishes interaction with host TMEM173/STING. LTCHE->VTSHD;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26405230;Dbxref=PMID:26405230	
P03255	UniProtKB	Mutagenesis	122	122	.	.	.	Note=Abolishes binding to UBE2I. L->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:8824223;Dbxref=PMID:8824223	
P03255	UniProtKB	Mutagenesis	123	123	.	.	.	Note=Abolishes increased sumoylation of human ZBED1. T->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25210186;Dbxref=PMID:25210186	
P03255	UniProtKB	Mutagenesis	154	154	.	.	.	Note=Loss of transactivation. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1835093;Dbxref=PMID:1835093	
P03255	UniProtKB	Mutagenesis	157	157	.	.	.	Note=Loss of transactivation. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1835093;Dbxref=PMID:1835093	
P03255	UniProtKB	Mutagenesis	171	171	.	.	.	Note=Loss of transactivation. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1835093;Dbxref=PMID:1835093	
P03255	UniProtKB	Mutagenesis	174	174	.	.	.	Note=Loss of transactivation. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1835093;Dbxref=PMID:1835093	
P03255	UniProtKB	Mutagenesis	253	253	.	.	.	Note=Reduces interaction with human ZBED1. K->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25210186;Dbxref=PMID:25210186	
P03255	UniProtKB	Mutagenesis	262	263	.	.	.	Note=Reduces interaction with human ZBED1. RR->EE;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25210186;Dbxref=PMID:25210186	
P03255	UniProtKB	Mutagenesis	267	267	.	.	.	Note=Reduces interaction with human ZBED1. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25210186;Dbxref=PMID:25210186	
P03255	UniProtKB	Mutagenesis	272	273	.	.	.	Note=Abolishes interaction with human ZBED1. Abolishes E1A-mediated increased sumoylation of ZBED1. Abolishes localization of ZBED1 to peripheral areas of PML bodies. LL->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25210186;Dbxref=PMID:25210186	
P03255	UniProtKB	Mutagenesis	281	282	.	.	.	Note=30%25 decrease in virus replication efficiency. Enhanced immortalization and Ras cooperative transformation. DL->AS;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23747199;Dbxref=PMID:23747199	
P03255	UniProtKB	Helix	43	46	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2R7G	
P03255	UniProtKB	Helix	59	63	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2KJE	
P03255	UniProtKB	Beta strand	68	70	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2KJE	
P03255	UniProtKB	Helix	72	74	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2KJE	
P03255	UniProtKB	Helix	80	82	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2KJE