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Protein

Fimbrial protein

Gene

pilA

Organism
Pseudomonas aeruginosa
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Fimbrial protein
Alternative name(s):
Pilin
Gene namesi
Name:pilA
Synonyms:fimA
OrganismiPseudomonas aeruginosa
Taxonomic identifieri287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Subcellular locationi

GO - Cellular componenti

  • pilus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Fimbrium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PropeptideiPRO_00000241761 – 61 Publication6
ChainiPRO_00000241777 – 150Fimbrial proteinAdd BLAST144

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei7N-methylphenylalanine1 Publication1
Disulfide bondi135 ↔ 148

Keywords - PTMi

Disulfide bond, Methylation

Interactioni

Subunit structurei

The pili are polar flexible filaments of about 5.4 nanometers diameter and 2.5 micrometers average length; they consist of only a single polypeptide chain arranged in a helical configuration of five subunits per turn in the assembled pilus.

Protein-protein interaction databases

IntActiP02973. 1 interactor.

Structurei

Secondary structure

1150
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi35 – 46Combined sources12
Helixi49 – 58Combined sources10
Beta strandi62 – 68Combined sources7
Turni72 – 75Combined sources4
Beta strandi76 – 78Combined sources3
Beta strandi90 – 98Combined sources9
Beta strandi100 – 102Combined sources3
Beta strandi104 – 109Combined sources6
Turni115 – 119Combined sources5
Beta strandi121 – 126Combined sources6
Turni128 – 130Combined sources3
Beta strandi133 – 137Combined sources5
Helixi141 – 143Combined sources3
Turni146 – 148Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1DZOX-ray1.63A35-150[»]
1NILNMR-A134-149[»]
1NIMNMR-A134-149[»]
1OQWX-ray2.00A/B7-150[»]
1PAJNMR-A134-149[»]
1PAKNMR-A134-149[»]
1X6PX-ray1.63A35-150[»]
1X6QX-ray1.51A35-150[»]
1X6RX-ray1.82A35-150[»]
1X6XX-ray0.96X35-150[»]
1X6YX-ray1.55A35-150[»]
1X6ZX-ray0.78A35-150[»]
2PY0X-ray1.35A35-149[»]
ProteinModelPortaliP02973.
SMRiP02973.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02973.

Family & Domainsi

Sequence similaritiesi

Belongs to the N-Me-Phe pilin family.Curated

Family and domain databases

InterProiIPR012902. N_methyl_site.
IPR001082. Pilin.
[Graphical view]
PfamiPF07963. N_methyl. 1 hit.
PF00114. Pilin. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02532. IV_pilin_GFxxxE. 1 hit.
PROSITEiPS00409. PROKAR_NTER_METHYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02973-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAQKGFTLI ELMIVVAIIG ILAAIAIPQY QNYVARSEGA SALASVNPLK
60 70 80 90 100
TTVEEALSRG WSVKSGTGTE DATKKEVPLG VAADANKLGT IALKPDPADG
110 120 130 140 150
TADITLTFTM GGAGPKNKGK IITLTRTAAD GLWKCTSDQD EQFIPKGCSR
Length:150
Mass (Da):15,650
Last modified:November 1, 1990 - v2
Checksum:iC0E35B69FD6FBE84
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti90T → TS AA sequence (PubMed:6131838).Curated1
Sequence conflicti101 – 103TAD → DTA AA sequence (PubMed:6131838).Curated3
Sequence conflicti128A → D in AAM26730 (PubMed:7903973).Curated1
Sequence conflicti150R → K in AAA25955 (PubMed:2430961).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14849 Genomic DNA. Translation: AAA25955.1.
X02402 Genomic DNA. Translation: CAA26248.1.
S67807 Genomic DNA. Translation: AAM26730.1.
PIRiA24603. YQPSPA.
RefSeqiWP_058135760.1. NZ_LLUB01000003.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14849 Genomic DNA. Translation: AAA25955.1.
X02402 Genomic DNA. Translation: CAA26248.1.
S67807 Genomic DNA. Translation: AAM26730.1.
PIRiA24603. YQPSPA.
RefSeqiWP_058135760.1. NZ_LLUB01000003.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1DZOX-ray1.63A35-150[»]
1NILNMR-A134-149[»]
1NIMNMR-A134-149[»]
1OQWX-ray2.00A/B7-150[»]
1PAJNMR-A134-149[»]
1PAKNMR-A134-149[»]
1X6PX-ray1.63A35-150[»]
1X6QX-ray1.51A35-150[»]
1X6RX-ray1.82A35-150[»]
1X6XX-ray0.96X35-150[»]
1X6YX-ray1.55A35-150[»]
1X6ZX-ray0.78A35-150[»]
2PY0X-ray1.35A35-149[»]
ProteinModelPortaliP02973.
SMRiP02973.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP02973. 1 interactor.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP02973.

Family and domain databases

InterProiIPR012902. N_methyl_site.
IPR001082. Pilin.
[Graphical view]
PfamiPF07963. N_methyl. 1 hit.
PF00114. Pilin. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02532. IV_pilin_GFxxxE. 1 hit.
PROSITEiPS00409. PROKAR_NTER_METHYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFMPA_PSEAI
AccessioniPrimary (citable) accession number: P02973
Secondary accession number(s): Q53390
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: November 1, 1990
Last modified: November 2, 2016
This is version 107 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.