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Protein

Lysine/arginine/ornithine-binding periplasmic protein

Gene

argT

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP.2 Publications

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-2377-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine/arginine/ornithine-binding periplasmic protein
Short name:
LAO-binding protein
Gene namesi
Name:argT
Ordered Locus Names:STM2355
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

  • Periplasm 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Add BLAST22
ChainiPRO_000003175023 – 260Lysine/arginine/ornithine-binding periplasmic proteinAdd BLAST238

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi60 ↔ 67

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP02911
PRIDEiP02911

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (HisP), two transmembrane proteins (HisM and HisQ) and a solute-binding protein (ArgT).1 Publication

Protein-protein interaction databases

STRINGi99287.STM2355

Structurei

Secondary structure

1260
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi26 – 32Combined sources7
Turni37 – 39Combined sources3
Beta strandi40 – 42Combined sources3
Beta strandi48 – 50Combined sources3
Helixi51 – 63Combined sources13
Beta strandi66 – 71Combined sources6
Helixi74 – 76Combined sources3
Helixi77 – 82Combined sources6
Beta strandi87 – 89Combined sources3
Helixi97 – 102Combined sources6
Beta strandi114 – 119Combined sources6
Helixi128 – 131Combined sources4
Beta strandi135 – 139Combined sources5
Helixi143 – 151Combined sources9
Helixi153 – 155Combined sources3
Beta strandi158 – 164Combined sources7
Helixi165 – 173Combined sources9
Beta strandi178 – 183Combined sources6
Helixi184 – 190Combined sources7
Turni191 – 193Combined sources3
Helixi195 – 197Combined sources3
Beta strandi200 – 202Combined sources3
Helixi210 – 213Combined sources4
Beta strandi215 – 217Combined sources3
Helixi226 – 241Combined sources16
Helixi244 – 250Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1LAFX-ray2.06E23-260[»]
1LAGX-ray2.06E23-260[»]
1LAHX-ray2.06E23-260[»]
1LSTX-ray1.80A23-260[»]
2LAOX-ray1.90A23-260[»]
ProteinModelPortaliP02911
SMRiP02911
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02911

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105E89 Bacteria
COG0834 LUCA
HOGENOMiHOG000031896
KOiK10013
OMAiFLEEPFT
PhylomeDBiP02911

Family and domain databases

InterProiView protein in InterPro
IPR005768 Lys_Arg_Orn-bd
IPR018313 SBP_3_CS
IPR001638 Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF00497 SBP_bac_3, 1 hit
SMARTiView protein in SMART
SM00062 PBPb, 1 hit
TIGRFAMsiTIGR01096 3A0103s03R, 1 hit
PROSITEiView protein in PROSITE
PS01039 SBP_BACTERIAL_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02911-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTVLALSL LIGLGATAAS YAALPQTVRI GTDTTYAPFS SKDAKGEFIG
60 70 80 90 100
FDIDLGNEMC KRMQVKCTWV ASDFDALIPS LKAKKIDAII SSLSITDKRQ
110 120 130 140 150
QEIAFSDKLY AADSRLIAAK GSPIQPTLES LKGKHVGVLQ GSTQEAYAND
160 170 180 190 200
NWRTKGVDVV AYANQDLIYS DLTAGRLDAA LQDEVAASEG FLKQPAGKEY
210 220 230 240 250
AFAGPSVKDK KYFGDGTGVG LRKDDTELKA AFDKALTELR QDGTYDKMAK
260
KYFDFNVYGD
Length:260
Mass (Da):28,200
Last modified:January 23, 2002 - v2
Checksum:iB996DE523F5F80A5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti124I → V in CAA24651 (PubMed:6273842).Curated1
Sequence conflicti124I → V in AAA75577 (PubMed:6273842).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01368 Genomic DNA Translation: CAA24651.1
J01805 Genomic DNA Translation: AAA75577.1
AE006468 Genomic DNA Translation: AAL21256.1
PIRiA03408 JKEBT
RefSeqiNP_461297.1, NC_003197.2
WP_000754423.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL21256; AAL21256; STM2355
GeneIDi1253877
KEGGistm:STM2355
PATRICifig|99287.12.peg.2492

Similar proteinsi

Entry informationi

Entry nameiARGT_SALTY
AccessioniPrimary (citable) accession number: P02911
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2002
Last modified: March 28, 2018
This is version 125 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health