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Protein

Lysine/arginine/ornithine-binding periplasmic protein

Gene

argT

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP.2 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2370-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine/arginine/ornithine-binding periplasmic protein
Short name:
LAO-binding protein
Gene namesi
Name:argT
Ordered Locus Names:STM2355
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

  • Periplasm 1 Publication

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Add
BLAST
Chaini23 – 260238Lysine/arginine/ornithine-binding periplasmic proteinPRO_0000031750Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi60 ↔ 67

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP02911.
PRIDEiP02911.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (HisP), two transmembrane proteins (HisM and HisQ) and a solute-binding protein (ArgT).1 Publication

Protein-protein interaction databases

STRINGi99287.STM2355.

Structurei

Secondary structure

1
260
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi26 – 327Combined sources
Turni37 – 393Combined sources
Beta strandi40 – 423Combined sources
Beta strandi48 – 503Combined sources
Helixi51 – 6313Combined sources
Beta strandi66 – 716Combined sources
Helixi74 – 763Combined sources
Helixi77 – 826Combined sources
Beta strandi87 – 893Combined sources
Helixi97 – 1026Combined sources
Beta strandi114 – 1196Combined sources
Helixi128 – 1314Combined sources
Beta strandi135 – 1395Combined sources
Helixi143 – 1519Combined sources
Helixi153 – 1553Combined sources
Beta strandi158 – 1647Combined sources
Helixi165 – 1739Combined sources
Beta strandi178 – 1836Combined sources
Helixi184 – 1907Combined sources
Turni191 – 1933Combined sources
Helixi195 – 1973Combined sources
Beta strandi200 – 2023Combined sources
Helixi210 – 2134Combined sources
Beta strandi215 – 2173Combined sources
Helixi226 – 24116Combined sources
Helixi244 – 2507Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1LAFX-ray2.06E23-260[»]
1LAGX-ray2.06E23-260[»]
1LAHX-ray2.06E23-260[»]
1LSTX-ray1.80A23-260[»]
2LAOX-ray1.90A23-260[»]
ProteinModelPortaliP02911.
SMRiP02911. Positions 23-260.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02911.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105E89. Bacteria.
COG0834. LUCA.
HOGENOMiHOG000031896.
KOiK10013.
OMAiNWRSKGV.
PhylomeDBiP02911.

Family and domain databases

InterProiIPR005768. Lys_Arg_Orn-bd.
IPR018313. SBP_3_CS.
IPR001638. Solute-binding_3/MltF_N.
[Graphical view]
PfamiPF00497. SBP_bac_3. 1 hit.
[Graphical view]
SMARTiSM00062. PBPb. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01096. 3A0103s03R. 1 hit.
PROSITEiPS01039. SBP_BACTERIAL_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02911-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTVLALSL LIGLGATAAS YAALPQTVRI GTDTTYAPFS SKDAKGEFIG
60 70 80 90 100
FDIDLGNEMC KRMQVKCTWV ASDFDALIPS LKAKKIDAII SSLSITDKRQ
110 120 130 140 150
QEIAFSDKLY AADSRLIAAK GSPIQPTLES LKGKHVGVLQ GSTQEAYAND
160 170 180 190 200
NWRTKGVDVV AYANQDLIYS DLTAGRLDAA LQDEVAASEG FLKQPAGKEY
210 220 230 240 250
AFAGPSVKDK KYFGDGTGVG LRKDDTELKA AFDKALTELR QDGTYDKMAK
260
KYFDFNVYGD
Length:260
Mass (Da):28,200
Last modified:January 23, 2002 - v2
Checksum:iB996DE523F5F80A5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti124 – 1241I → V in CAA24651 (PubMed:6273842).Curated
Sequence conflicti124 – 1241I → V in AAA75577 (PubMed:6273842).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01368 Genomic DNA. Translation: CAA24651.1.
J01805 Genomic DNA. Translation: AAA75577.1.
AE006468 Genomic DNA. Translation: AAL21256.1.
PIRiA03408. JKEBT.
RefSeqiNP_461297.1. NC_003197.1.
WP_000754423.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL21256; AAL21256; STM2355.
GeneIDi1253877.
KEGGistm:STM2355.
PATRICi32383325. VBISalEnt20916_2492.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01368 Genomic DNA. Translation: CAA24651.1.
J01805 Genomic DNA. Translation: AAA75577.1.
AE006468 Genomic DNA. Translation: AAL21256.1.
PIRiA03408. JKEBT.
RefSeqiNP_461297.1. NC_003197.1.
WP_000754423.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1LAFX-ray2.06E23-260[»]
1LAGX-ray2.06E23-260[»]
1LAHX-ray2.06E23-260[»]
1LSTX-ray1.80A23-260[»]
2LAOX-ray1.90A23-260[»]
ProteinModelPortaliP02911.
SMRiP02911. Positions 23-260.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM2355.

Proteomic databases

PaxDbiP02911.
PRIDEiP02911.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL21256; AAL21256; STM2355.
GeneIDi1253877.
KEGGistm:STM2355.
PATRICi32383325. VBISalEnt20916_2492.

Phylogenomic databases

eggNOGiENOG4105E89. Bacteria.
COG0834. LUCA.
HOGENOMiHOG000031896.
KOiK10013.
OMAiNWRSKGV.
PhylomeDBiP02911.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2370-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP02911.

Family and domain databases

InterProiIPR005768. Lys_Arg_Orn-bd.
IPR018313. SBP_3_CS.
IPR001638. Solute-binding_3/MltF_N.
[Graphical view]
PfamiPF00497. SBP_bac_3. 1 hit.
[Graphical view]
SMARTiSM00062. PBPb. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01096. 3A0103s03R. 1 hit.
PROSITEiPS01039. SBP_BACTERIAL_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARGT_SALTY
AccessioniPrimary (citable) accession number: P02911
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2002
Last modified: September 7, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.