Skip Header

Contribute Send feedback
Read comments (?) or add your own

P02884 (THM2_THADA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Thaumatin-2
Alternative name(s):
Thaumatin II
OrganismThaumatococcus daniellii (Katemfe) (Phrynium daniellii)
Taxonomic identifier4621 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Zingiberales › Marantaceae › Thaumatococcus

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Taste-modifying protein; intensely sweet-tasting. It is 100000 times sweeter than sucrose on a molar basis.

Subcellular location

Cytoplasmic vesicle. Note: Thaumatin accumulates in vesicle-like organelles.

Sequence similarities

Belongs to the thaumatin family.

Ontologies

Keywords
   Cellular componentCytoplasmic vesicle
   DomainSignal
   Molecular functionTaste-modifying protein
   PTMDisulfide bond
   Technical term3D-structure
Gene Ontology (GO)
   Cellular_componentcytoplasmic membrane-bounded vesicle

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Probable
Chain23 – 229207Thaumatin-2
PRO_0000034017
Propeptide230 – 2356 Potential
PRO_0000034018

Amino acid modifications

Disulfide bond31 ↔ 226 By similarity
Disulfide bond78 ↔ 88 By similarity
Disulfide bond93 ↔ 99 By similarity
Disulfide bond143 ↔ 215 By similarity
Disulfide bond148 ↔ 199 By similarity
Disulfide bond156 ↔ 167 By similarity
Disulfide bond171 ↔ 180 By similarity
Disulfide bond181 ↔ 186 By similarity

Secondary structure

1 ............................................ 235
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P02884 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 15E9DA82554D7A75

FASTA23525,523
        10         20         30         40         50         60 
MAATTCFFFL FPFLLLLTLS RAATFEIVNR CSYTVWAAAS KGDAALDAGG RQLNSGESWT 

        70         80         90        100        110        120 
INVEPGTKGG KIWARTDCYF DDSGRGICRT GDCGGLLQCK RFGRPPTTLA EFSLNQYGKD 

       130        140        150        160        170        180 
YIDISNIKGF NVPMDFSPTT RGCRGVRCAA DIVGQCPAKL KAPGGGCNDA CTVFQTSEYC 

       190        200        210        220        230 
CTTGKCGPTE YSRFFKRLCP DAFSYVLDKP TTVTCPGSSN YRVTFCPTAL ELEDE

« Hide

References

[1]"Cloning of cDNA encoding the sweet-tasting plant protein thaumatin and its expression in Escherichia coli."
Edens L., Heslinga L., Klok R., Ledeboer A.M., Maat J., Toonen M.Y., Visser C., Verrips C.T.
Gene 18:1-12(1982) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		J01209 mRNA. Translation: AAA93095.1.
PIRQTTC2. A03378.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3AOKX-ray1.27A23-229[»]
ProteinModelPortalP02884.
SMRP02884. Positions 23-229.
ModBaseSearch...

Protein family/group databases

Allergome9233. Tha da TLP.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.110.10. 1 hit.
InterProIPR001938. Thaumatin.
IPR017949. Thaumatin_CS.
[Graphical view]
PfamPF00314. Thaumatin. 1 hit.
[Graphical view]
PIRSFPIRSF002703. Thaumatin. 1 hit.
PRINTSPR00347. THAUMATIN.
SMARTSM00205. THN. 1 hit.
[Graphical view]
SUPFAMSSF49870. Thaumatin. 1 hit.
PROSITEPS00316. THAUMATIN_1. 1 hit.
PS51367. THAUMATIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTHM2_THADA
AccessionPrimary (citable) accession number: P02884
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: April 3, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents