Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P02883

- THM1_THADA

UniProt

P02883 - THM1_THADA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Thaumatin-1

Gene
N/A
Organism
Thaumatococcus daniellii (Katemfe) (Phrynium daniellii)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Taste-modifying protein; intensely sweet-tasting. It is 100000 times sweeter than sucrose on a molar basis.

Keywords - Molecular functioni

Taste-modifying protein

Names & Taxonomyi

Protein namesi
Recommended name:
Thaumatin-1
Alternative name(s):
Thaumatin I
OrganismiThaumatococcus daniellii (Katemfe) (Phrynium daniellii)
Taxonomic identifieri4621 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaZingiberalesMarantaceaeThaumatococcus

Subcellular locationi

Cytoplasmic vesicle
Note: Thaumatin accumulates in vesicle-like organelles.

GO - Cellular componenti

  1. cytoplasmic vesicle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasmic vesicle

Pathology & Biotechi

Protein family/group databases

Allergomei9233. Tha da TLP.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 207207Thaumatin-1PRO_0000096221Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi9 ↔ 2041 PublicationPROSITE-ProRule annotation
Disulfide bondi56 ↔ 661 PublicationPROSITE-ProRule annotation
Disulfide bondi71 ↔ 771 PublicationPROSITE-ProRule annotation
Disulfide bondi121 ↔ 1931 PublicationPROSITE-ProRule annotation
Disulfide bondi126 ↔ 1771 PublicationPROSITE-ProRule annotation
Disulfide bondi134 ↔ 1451 PublicationPROSITE-ProRule annotation
Disulfide bondi149 ↔ 1581 PublicationPROSITE-ProRule annotation
Disulfide bondi159 ↔ 1641 PublicationPROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

1
207
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 76Combined sources
Beta strandi9 – 113Combined sources
Beta strandi13 – 186Combined sources
Beta strandi20 – 3112Combined sources
Beta strandi36 – 405Combined sources
Beta strandi47 – 559Combined sources
Beta strandi62 – 654Combined sources
Beta strandi67 – 693Combined sources
Beta strandi74 – 763Combined sources
Beta strandi87 – 948Combined sources
Beta strandi97 – 1037Combined sources
Beta strandi108 – 1103Combined sources
Beta strandi112 – 1209Combined sources
Beta strandi124 – 1263Combined sources
Helixi130 – 1334Combined sources
Helixi136 – 1383Combined sources
Beta strandi143 – 1453Combined sources
Helixi148 – 1525Combined sources
Helixi155 – 1584Combined sources
Turni159 – 1613Combined sources
Helixi168 – 1769Combined sources
Beta strandi180 – 1834Combined sources
Beta strandi191 – 1944Combined sources
Beta strandi199 – 2046Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1KWNX-ray1.20A1-207[»]
1LR2X-ray1.80A1-207[»]
1LR3X-ray1.80A1-207[»]
1LXZX-ray1.25A1-207[»]
1LY0X-ray1.36A1-207[»]
1PP3X-ray1.60A/B1-207[»]
1RQWX-ray1.05A1-207[»]
1THIX-ray3.20A1-207[»]
1THUX-ray2.60A1-207[»]
1THVX-ray1.75A1-207[»]
1THWX-ray1.75A1-207[»]
2A7IX-ray1.75X1-207[»]
2BLRX-ray1.40A1-206[»]
2BLUX-ray1.40A1-206[»]
2D8OX-ray2.38A1-207[»]
2D8PX-ray2.30A1-207[»]
2G4YX-ray1.98A1-207[»]
2OQNX-ray1.90A1-207[»]
2PE7X-ray1.46A1-207[»]
2VHKX-ray0.94A1-206[»]
2VHRX-ray0.95A1-207[»]
2VI1X-ray1.04A1-207[»]
2VI2X-ray1.08A1-207[»]
2VI3X-ray0.98A1-207[»]
2VI4X-ray1.10A1-207[»]
2VU6X-ray0.95A1-207[»]
2VU7X-ray1.08A1-207[»]
2WBZX-ray1.60A1-206[»]
3AL7X-ray1.10A1-207[»]
3ALDX-ray1.10A1-207[»]
3DZNX-ray1.51A1-207[»]
3DZPX-ray1.51A1-207[»]
3DZRX-ray1.51A1-207[»]
3E0AX-ray1.51A1-207[»]
3E3SX-ray1.73A1-207[»]
3N02X-ray1.50A1-206[»]
3N03X-ray1.50A1-206[»]
3QY5X-ray1.25A1-207[»]
3V7VX-ray2.30A1-207[»]
3V82X-ray2.30A1-207[»]
3V84X-ray2.30A1-207[»]
3V87X-ray2.30A1-207[»]
3V88X-ray2.30A1-207[»]
3V8AX-ray2.30A1-207[»]
3VCEX-ray2.30A1-207[»]
3VCGX-ray2.30A1-207[»]
3VCHX-ray2.30A1-207[»]
3VCIX-ray2.30A1-207[»]
3VCJX-ray2.30A1-207[»]
3VCKX-ray2.30A1-207[»]
3VHFX-ray1.39A1-207[»]
3VHGX-ray1.00A1-207[»]
3VJQX-ray1.00A1-207[»]
3ZEJX-ray1.55A1-207[»]
4AXRX-ray1.38A1-207[»]
4AXUX-ray1.38A1-206[»]
4BALX-ray1.30A1-207[»]
4BARX-ray1.20A1-207[»]
4C3CX-ray1.80A1-207[»]
4DC5X-ray1.48A1-207[»]
4DC6X-ray1.48A1-207[»]
4DIYX-ray1.98A1-207[»]
4DIZX-ray1.98A1-207[»]
4DJ0X-ray1.98A1-207[»]
4DJ1X-ray1.98A1-207[»]
4EK0X-ray1.52A1-207[»]
4EKAX-ray1.55A1-207[»]
4EKBX-ray1.52A1-207[»]
4EKHX-ray1.75A1-207[»]
4EKOX-ray1.52A1-207[»]
4EKTX-ray1.75A1-207[»]
4EL2X-ray1.52A1-207[»]
4EL3X-ray1.95A1-207[»]
4EL7X-ray1.52A1-207[»]
4ELAX-ray2.00A1-207[»]
4TVTX-ray1.20A1-207[»]
ProteinModelPortaliP02883.
SMRiP02883. Positions 1-207.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02883.

Family & Domainsi

Sequence similaritiesi

Belongs to the thaumatin family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di2.60.110.10. 1 hit.
InterProiIPR001938. Thaumatin.
IPR017949. Thaumatin_CS.
[Graphical view]
PANTHERiPTHR31048. PTHR31048. 1 hit.
PfamiPF00314. Thaumatin. 1 hit.
[Graphical view]
PIRSFiPIRSF002703. Thaumatin. 1 hit.
PRINTSiPR00347. THAUMATIN.
SMARTiSM00205. THN. 1 hit.
[Graphical view]
SUPFAMiSSF49870. SSF49870. 1 hit.
PROSITEiPS00316. THAUMATIN_1. 1 hit.
PS51367. THAUMATIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P02883-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
ATFEIVNRCS YTVWAAASKG DAALDAGGRQ LNSGESWTIN VEPGTNGGKI
60 70 80 90 100
WARTDCYFDD SGSGICKTGD CGGLLRCKRF GRPPTTLAEF SLNQYGKDYI
110 120 130 140 150
DISNIKGFNV PMNFSPTTRG CRGVRCAADI VGQCPAKLKA PGGGCNDACT
160 170 180 190 200
VFQTSEYCCT TGKCGPTEYS RFFKRLCPDA FSYVLDKPTT VTCPGSSNYR

VTFCPTA
Length:207
Mass (Da):22,204
Last modified:July 21, 1986 - v1
Checksum:i9C3288F1873FB32B
GO

Sequence databases

PIRiA03377. QTTC1.

Cross-referencesi

Sequence databases

PIRi A03377. QTTC1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1KWN X-ray 1.20 A 1-207 [» ]
1LR2 X-ray 1.80 A 1-207 [» ]
1LR3 X-ray 1.80 A 1-207 [» ]
1LXZ X-ray 1.25 A 1-207 [» ]
1LY0 X-ray 1.36 A 1-207 [» ]
1PP3 X-ray 1.60 A/B 1-207 [» ]
1RQW X-ray 1.05 A 1-207 [» ]
1THI X-ray 3.20 A 1-207 [» ]
1THU X-ray 2.60 A 1-207 [» ]
1THV X-ray 1.75 A 1-207 [» ]
1THW X-ray 1.75 A 1-207 [» ]
2A7I X-ray 1.75 X 1-207 [» ]
2BLR X-ray 1.40 A 1-206 [» ]
2BLU X-ray 1.40 A 1-206 [» ]
2D8O X-ray 2.38 A 1-207 [» ]
2D8P X-ray 2.30 A 1-207 [» ]
2G4Y X-ray 1.98 A 1-207 [» ]
2OQN X-ray 1.90 A 1-207 [» ]
2PE7 X-ray 1.46 A 1-207 [» ]
2VHK X-ray 0.94 A 1-206 [» ]
2VHR X-ray 0.95 A 1-207 [» ]
2VI1 X-ray 1.04 A 1-207 [» ]
2VI2 X-ray 1.08 A 1-207 [» ]
2VI3 X-ray 0.98 A 1-207 [» ]
2VI4 X-ray 1.10 A 1-207 [» ]
2VU6 X-ray 0.95 A 1-207 [» ]
2VU7 X-ray 1.08 A 1-207 [» ]
2WBZ X-ray 1.60 A 1-206 [» ]
3AL7 X-ray 1.10 A 1-207 [» ]
3ALD X-ray 1.10 A 1-207 [» ]
3DZN X-ray 1.51 A 1-207 [» ]
3DZP X-ray 1.51 A 1-207 [» ]
3DZR X-ray 1.51 A 1-207 [» ]
3E0A X-ray 1.51 A 1-207 [» ]
3E3S X-ray 1.73 A 1-207 [» ]
3N02 X-ray 1.50 A 1-206 [» ]
3N03 X-ray 1.50 A 1-206 [» ]
3QY5 X-ray 1.25 A 1-207 [» ]
3V7V X-ray 2.30 A 1-207 [» ]
3V82 X-ray 2.30 A 1-207 [» ]
3V84 X-ray 2.30 A 1-207 [» ]
3V87 X-ray 2.30 A 1-207 [» ]
3V88 X-ray 2.30 A 1-207 [» ]
3V8A X-ray 2.30 A 1-207 [» ]
3VCE X-ray 2.30 A 1-207 [» ]
3VCG X-ray 2.30 A 1-207 [» ]
3VCH X-ray 2.30 A 1-207 [» ]
3VCI X-ray 2.30 A 1-207 [» ]
3VCJ X-ray 2.30 A 1-207 [» ]
3VCK X-ray 2.30 A 1-207 [» ]
3VHF X-ray 1.39 A 1-207 [» ]
3VHG X-ray 1.00 A 1-207 [» ]
3VJQ X-ray 1.00 A 1-207 [» ]
3ZEJ X-ray 1.55 A 1-207 [» ]
4AXR X-ray 1.38 A 1-207 [» ]
4AXU X-ray 1.38 A 1-206 [» ]
4BAL X-ray 1.30 A 1-207 [» ]
4BAR X-ray 1.20 A 1-207 [» ]
4C3C X-ray 1.80 A 1-207 [» ]
4DC5 X-ray 1.48 A 1-207 [» ]
4DC6 X-ray 1.48 A 1-207 [» ]
4DIY X-ray 1.98 A 1-207 [» ]
4DIZ X-ray 1.98 A 1-207 [» ]
4DJ0 X-ray 1.98 A 1-207 [» ]
4DJ1 X-ray 1.98 A 1-207 [» ]
4EK0 X-ray 1.52 A 1-207 [» ]
4EKA X-ray 1.55 A 1-207 [» ]
4EKB X-ray 1.52 A 1-207 [» ]
4EKH X-ray 1.75 A 1-207 [» ]
4EKO X-ray 1.52 A 1-207 [» ]
4EKT X-ray 1.75 A 1-207 [» ]
4EL2 X-ray 1.52 A 1-207 [» ]
4EL3 X-ray 1.95 A 1-207 [» ]
4EL7 X-ray 1.52 A 1-207 [» ]
4ELA X-ray 2.00 A 1-207 [» ]
4TVT X-ray 1.20 A 1-207 [» ]
ProteinModelPortali P02883.
SMRi P02883. Positions 1-207.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 9233. Tha da TLP.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P02883.

Family and domain databases

Gene3Di 2.60.110.10. 1 hit.
InterProi IPR001938. Thaumatin.
IPR017949. Thaumatin_CS.
[Graphical view ]
PANTHERi PTHR31048. PTHR31048. 1 hit.
Pfami PF00314. Thaumatin. 1 hit.
[Graphical view ]
PIRSFi PIRSF002703. Thaumatin. 1 hit.
PRINTSi PR00347. THAUMATIN.
SMARTi SM00205. THN. 1 hit.
[Graphical view ]
SUPFAMi SSF49870. SSF49870. 1 hit.
PROSITEi PS00316. THAUMATIN_1. 1 hit.
PS51367. THAUMATIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: PROTEIN SEQUENCE.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS).
  3. "X-ray analysis of new crystal forms of the sweet protein thaumatin."
    McPherson A., Weickmann J.
    J. Biomol. Struct. Dyn. 7:1053-1060(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS).
  4. "Crystal structure of a sweet tasting protein thaumatin I, at 1.65-A resolution."
    Ogata C.M., Gordon P.F., de Vos A.M., Kim S.-H.
    J. Mol. Biol. 228:893-908(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS).

Entry informationi

Entry nameiTHM1_THADA
AccessioniPrimary (citable) accession number: P02883
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 26, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3