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Protein

Monellin chain B

Gene
N/A
Organism
Dioscoreophyllum cumminsii (Serendipity berry) (Rhopalandria cumminsii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Taste-modifying protein; intensely sweet-tasting protein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei41 – 411Blocking, abolishes the sweet taste

Keywords - Molecular functioni

Taste-modifying protein

Names & Taxonomyi

Protein namesi
Recommended name:
Monellin chain B
Alternative name(s):
Monellin chain II
OrganismiDioscoreophyllum cumminsii (Serendipity berry) (Rhopalandria cumminsii)
Taxonomic identifieri3457 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsRanunculalesMenispermaceaeTinosporoideaeDioscoreophyllum

Pathology & Biotechi

Biotechnological usei

Natural monellin has not been mass marketed to the food industry, primarily due to the challenge of large-scale purification of the protein which is relatively sensitive to heat or acid treatment.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 5050Monellin chain BPRO_0000207166Add
BLAST

Interactioni

Subunit structurei

Heterodimer of an A chain and a B chain.

Protein-protein interaction databases

MINTiMINT-1542289.

Structurei

Secondary structure

1
50
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 63Combined sources
Helixi10 – 2617Combined sources
Beta strandi28 – 303Combined sources
Beta strandi34 – 4714Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FA3NMR-A1-48[»]
1FUWNMR-A1-48[»]
1IV7X-ray1.82A/B1-48[»]
1IV9X-ray1.90A/B1-50[»]
1KRLX-ray1.90B/D1-50[»]
1M9GNMR-A1-48[»]
1MNLNMR-A1-48[»]
1MOLX-ray1.70A/B1-48[»]
2O9UX-ray1.15X1-48[»]
3MONX-ray2.80B/D/F/H1-48[»]
3PXMX-ray1.80A/B1-48[»]
3PYJX-ray2.00A1-48[»]
3Q2PX-ray2.34A/B/C/D1-48[»]
4MONX-ray2.30B/D1-48[»]
ProteinModelPortaliP02882.
SMRiP02882. Positions 1-50.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02882.

Family & Domainsi

Family and domain databases

InterProiIPR015283. Monellin.
IPR002095. Monellin_B.
[Graphical view]
PfamiPF09200. Monellin. 1 hit.
[Graphical view]
PRINTSiPR00631. MONELLINB.

Sequencei

Sequence statusi: Complete.

P02882-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GEWEIIDIGP FTQNLGKFAV DEENKIGQYG RLTFNKVIRP CMKKTIYEEN
Length:50
Mass (Da):5,835
Last modified:August 1, 1991 - v2
Checksum:iF08396DFCD480C81
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti49 – 502EN → NE AA sequence (PubMed:964918).Curated

Sequence databases

PIRiJH0210. MLDIB.

Cross-referencesi

Sequence databases

PIRiJH0210. MLDIB.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FA3NMR-A1-48[»]
1FUWNMR-A1-48[»]
1IV7X-ray1.82A/B1-48[»]
1IV9X-ray1.90A/B1-50[»]
1KRLX-ray1.90B/D1-50[»]
1M9GNMR-A1-48[»]
1MNLNMR-A1-48[»]
1MOLX-ray1.70A/B1-48[»]
2O9UX-ray1.15X1-48[»]
3MONX-ray2.80B/D/F/H1-48[»]
3PXMX-ray1.80A/B1-48[»]
3PYJX-ray2.00A1-48[»]
3Q2PX-ray2.34A/B/C/D1-48[»]
4MONX-ray2.30B/D1-48[»]
ProteinModelPortaliP02882.
SMRiP02882. Positions 1-50.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1542289.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP02882.

Family and domain databases

InterProiIPR015283. Monellin.
IPR002095. Monellin_B.
[Graphical view]
PfamiPF09200. Monellin. 1 hit.
[Graphical view]
PRINTSiPR00631. MONELLINB.
ProtoNetiSearch...

Entry informationi

Entry nameiMONB_DIOCU
AccessioniPrimary (citable) accession number: P02882
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: August 1, 1991
Last modified: May 11, 2016
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.