ID   MPAA5_AMBEL             Reviewed;          45 AA.
AC   P02878;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   22-FEB-2023, entry version 73.
DE   RecName: Full=Pollen allergen Amb a 5;
DE   AltName: Full=Allergen Amb a V;
DE   AltName: Full=Allergen Ra5;
DE   AltName: Allergen=Amb a 5;
OS   Ambrosia artemisiifolia var. elatior (Short ragweed) (Ambrosia elatior).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Heliantheae; Ambrosia.
OX   NCBI_TaxID=4215;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Pollen;
RX   PubMed=1122277; DOI=10.1021/bi00677a019;
RA   Mole L.E., Goodfriend L., Lapkoff C.B., Kehoe J.M., Capra J.D.;
RT   "The amino acid sequence of ragweed pollen allergen Ra5.";
RL   Biochemistry 14:1216-1220(1975).
RN   [2]
RP   STRUCTURE BY NMR.
RX   PubMed=1390654; DOI=10.1021/bi00152a003;
RA   Metzler W.J., Valentine K., Roebber M., Marsh D.G., Mueller L.;
RT   "Proton resonance assignments and three-dimensional solution structure of
RT   the ragweed allergen Amb a V by nuclear magnetic resonance spectroscopy.";
RL   Biochemistry 31:8697-8705(1992).
CC   -!- SUBUNIT: Monomer.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
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DR   PIR; A03371; ARRA5.
DR   AlphaFoldDB; P02878; -.
DR   SMR; P02878; -.
DR   Allergome; 28; Amb a 5.
DR   Allergome; 3069; Amb a 5.0101.
DR   Gene3D; 3.30.160.80; Amb V Allergen; 1.
DR   InterPro; IPR005611; Amb_V_allergen.
DR   InterPro; IPR036712; Amb_V_allergen_sf.
DR   Pfam; PF03913; Ragweed_pollen; 1.
DR   PIRSF; PIRSF002697; Amb_V_allergen; 1.
DR   SMART; SM00816; Amb_V_allergen; 1.
DR   SUPFAM; SSF57296; Amb V allergen; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Disulfide bond.
FT   CHAIN           1..45
FT                   /note="Pollen allergen Amb a 5"
FT                   /id="PRO_0000096552"
FT   DISULFID        4..39
FT   DISULFID        11..26
FT   DISULFID        18..32
FT   DISULFID        19..43
FT   VARIANT         2
FT                   /note="V -> L (in 33% of the molecules)"
SQ   SEQUENCE   45 AA;  4979 MW;  92870A6D4CBCCA7C CRC64;
     LVPCAWAGNV CGEKRAYCCS DPGRYCPWQV VCYESSEICS KKCGK
//