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P02878 (MPAA5_AMBEL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pollen allergen Amb a 5
Alternative name(s):
Allergen Amb a V
Allergen Ra5
Allergen=Amb a 5
OrganismAmbrosia artemisiifolia var. elatior (Short ragweed) (Ambrosia elatior)
Taxonomic identifier4215 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeHeliantheae allianceHeliantheaeAmbrosia

Protein attributes

Sequence length45 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Monomer.

Allergenic properties

Causes an allergic reaction in human.

Ontologies

Keywords
   DiseaseAllergen
   PTMDisulfide bond
   Technical termDirect protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4545Pollen allergen Amb a 5
PRO_0000096552

Amino acid modifications

Disulfide bond4 ↔ 39
Disulfide bond11 ↔ 26
Disulfide bond18 ↔ 32
Disulfide bond19 ↔ 43

Natural variations

Natural variant21V → L in 33% of the molecules.

Sequences

Sequence LengthMass (Da)Tools
P02878 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 92870A6D4CBCCA7C

FASTA454,979
        10         20         30         40 
LVPCAWAGNV CGEKRAYCCS DPGRYCPWQV VCYESSEICS KKCGK 

« Hide

References

[1]"The amino acid sequence of ragweed pollen allergen Ra5."
Mole L.E., Goodfriend L., Lapkoff C.B., Kehoe J.M., Capra J.D.
Biochemistry 14:1216-1220(1975) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Pollen.
[2]"Proton resonance assignments and three-dimensional solution structure of the ragweed allergen Amb a V by nuclear magnetic resonance spectroscopy."
Metzler W.J., Valentine K., Roebber M., Marsh D.G., Mueller L.
Biochemistry 31:8697-8705(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR.

Cross-references

Sequence databases

PIRARRA5. A03371.

3D structure databases

ProteinModelPortalP02878.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome28. Amb a 5.
3069. Amb a 5.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.160.80. 1 hit.
InterProIPR005611. Amb_V_allergen.
[Graphical view]
PfamPF03913. Amb_V_allergen. 1 hit.
[Graphical view]
PIRSFPIRSF002697. Amb_V_allergen. 1 hit.
ProDomPD018950. Amb_V_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00816. Amb_V_allergen. 1 hit.
[Graphical view]
SUPFAMSSF57296. SSF57296. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMPAA5_AMBEL
AccessionPrimary (citable) accession number: P02878
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Allergens

Nomenclature of allergens and list of entries