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Protein

Metallothionein-2

Gene
N/A
Organism
Scylla serrata (Mud crab)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Metallothioneins have a high content of cysteine residues that bind various heavy metals. Class I MTS in marine crustacea are involved in the sequestration of elevated levels of heavy-metal ions.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi4Divalent metal cation; cluster B1
Metal bindingi5Divalent metal cation; cluster B1
Metal bindingi9Divalent metal cation; cluster B1
Metal bindingi11Divalent metal cation; cluster B1
Metal bindingi16Divalent metal cation; cluster B1
Metal bindingi20Divalent metal cation; cluster B1
Metal bindingi22Divalent metal cation; cluster B1
Metal bindingi25Divalent metal cation; cluster B1
Metal bindingi27Divalent metal cation; cluster B1
Metal bindingi30Divalent metal cation; cluster A1
Metal bindingi33Divalent metal cation; cluster A1
Metal bindingi37Divalent metal cation; cluster A1
Metal bindingi39Divalent metal cation; cluster A1
Metal bindingi45Divalent metal cation; cluster A1
Metal bindingi49Divalent metal cation; cluster A1
Metal bindingi53Divalent metal cation; cluster A1
Metal bindingi55Divalent metal cation; cluster A1
Metal bindingi56Divalent metal cation; cluster A1

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-2
Short name:
MT-2
Alternative name(s):
Metallothionein-II
Short name:
MT-II
OrganismiScylla serrata (Mud crab)
Taxonomic identifieri6761 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataBrachyuraEubrachyuraPortunoideaPortunidaeScylla

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001973411 – 57Metallothionein-2Add BLAST57

Structurei

3D structure databases

ProteinModelPortaliP02806.
SMRiP02806.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 28BetaAdd BLAST28
Regioni29 – 57AlphaAdd BLAST29

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR002045. Metalthion_crustacean.
IPR017854. Metalthion_dom.
PRINTSiPR00858. MTCRUSTACEAN.
SUPFAMiSSF57868. SSF57868. 2 hits.

Sequencei

Sequence statusi: Complete.

P02806-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PDPCCNDKCD CKEGECKTGC KCTSCRCPPC EQCSSGCKCA NKEDCRKTCS

KPCSCCP
Length:57
Mass (Da):6,109
Last modified:July 21, 1986 - v1
Checksum:i8C2B3F6A6BAA3611
GO

Sequence databases

PIRiA03284. SMKD2S.

Similar proteinsi

Entry informationi

Entry nameiMT2_SCYSE
AccessioniPrimary (citable) accession number: P02806
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 10, 2017
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Metallothioneins
    Classification of metallothioneins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families