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P02407

- RS17A_YEAST

UniProt

P02407 - RS17A_YEAST

Protein

40S ribosomal protein S17-A

Gene

RPS17A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 121 (01 Oct 2014)
      Sequence version 1 (21 Jul 1986)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: SGD

    GO - Biological processi

    1. cytoplasmic translation Source: SGD
    2. ribosomal small subunit assembly Source: SGD

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32626-MONOMER.
    ReactomeiREACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S17-A
    Alternative name(s):
    RP51A
    Gene namesi
    Name:RPS17A
    Synonyms:RP51A
    Ordered Locus Names:YML024W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIII

    Organism-specific databases

    CYGDiYML024w.
    SGDiS000004486. RPS17A.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: SGD

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13613640S ribosomal protein S17-APRO_0000141546Add
    BLAST

    Proteomic databases

    PaxDbiP02407.
    PRIDEiP02407.

    Expressioni

    Gene expression databases

    GenevestigatoriP02407.

    Interactioni

    Subunit structurei

    Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

    Protein-protein interaction databases

    BioGridi35145. 72 interactions.
    IntActiP02407. 62 interactions.
    MINTiMINT-8285645.
    STRINGi4932.YML024W.

    Structurei

    Secondary structure

    1
    136
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi7 – 2014
    Turni21 – 233
    Helixi28 – 3811
    Beta strandi40 – 434
    Helixi44 – 6118
    Helixi73 – 797
    Beta strandi97 – 993
    Helixi104 – 11310

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1VW9electron microscopy6.10S1-136[»]
    1VWVelectron microscopy6.10S1-136[»]
    3IZBelectron microscopy-Q1-136[»]
    3O2ZX-ray4.00K1-136[»]
    3O30X-ray4.00K1-136[»]
    3U5CX-ray3.00R1-136[»]
    3U5GX-ray3.00R1-136[»]
    4BYLelectron microscopy4.30R1-136[»]
    4BYTelectron microscopy6.60R1-136[»]
    4CUYelectron microscopy3.70R2-125[»]
    ProteinModelPortaliP02407.
    SMRiP02407. Positions 2-122.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S17e family.Curated

    Phylogenomic databases

    eggNOGiCOG1383.
    GeneTreeiENSGT00390000006548.
    HOGENOMiHOG000227166.
    KOiK02962.
    OMAiNKVAGFS.
    OrthoDBiEOG7G4QT6.

    Family and domain databases

    Gene3Di1.10.60.20. 1 hit.
    HAMAPiMF_00511. Ribosomal_S17e.
    InterProiIPR001210. Ribosomal_S17e.
    IPR018273. Ribosomal_S17e_CS.
    [Graphical view]
    PANTHERiPTHR10732. PTHR10732. 1 hit.
    PfamiPF00833. Ribosomal_S17e. 1 hit.
    [Graphical view]
    SUPFAMiSSF116820. SSF116820. 1 hit.
    PROSITEiPS00712. RIBOSOMAL_S17E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P02407-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGRVRTKTVK RASKALIERY YPKLTLDFQT NKRLCDEIAT IQSKRLRNKI    50
    AGYTTHLMKR IQKGPVRGIS FKLQEEERER KDQYVPEVSA LDLSRSNGVL 100
    NVDNQTSDLV KSLGLKLPLS VINVSAQRDR RYRKRV 136
    Length:136
    Mass (Da):15,788
    Last modified:July 21, 1986 - v1
    Checksum:i956E5382870EA289
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    J01349 Genomic DNA. Translation: AAA88733.1.
    Z46659 Genomic DNA. Translation: CAA86631.1.
    BK006946 Genomic DNA. Translation: DAA09874.1.
    PIRiA02784. R5BY51.
    RefSeqiNP_013688.1. NM_001182382.1.

    Genome annotation databases

    EnsemblFungiiYML024W; YML024W; YML024W.
    GeneIDi854984.
    KEGGisce:YML024W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    J01349 Genomic DNA. Translation: AAA88733.1 .
    Z46659 Genomic DNA. Translation: CAA86631.1 .
    BK006946 Genomic DNA. Translation: DAA09874.1 .
    PIRi A02784. R5BY51.
    RefSeqi NP_013688.1. NM_001182382.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1VW9 electron microscopy 6.10 S 1-136 [» ]
    1VWV electron microscopy 6.10 S 1-136 [» ]
    3IZB electron microscopy - Q 1-136 [» ]
    3O2Z X-ray 4.00 K 1-136 [» ]
    3O30 X-ray 4.00 K 1-136 [» ]
    3U5C X-ray 3.00 R 1-136 [» ]
    3U5G X-ray 3.00 R 1-136 [» ]
    4BYL electron microscopy 4.30 R 1-136 [» ]
    4BYT electron microscopy 6.60 R 1-136 [» ]
    4CUY electron microscopy 3.70 R 2-125 [» ]
    ProteinModelPortali P02407.
    SMRi P02407. Positions 2-122.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35145. 72 interactions.
    IntActi P02407. 62 interactions.
    MINTi MINT-8285645.
    STRINGi 4932.YML024W.

    Proteomic databases

    PaxDbi P02407.
    PRIDEi P02407.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YML024W ; YML024W ; YML024W .
    GeneIDi 854984.
    KEGGi sce:YML024W.

    Organism-specific databases

    CYGDi YML024w.
    SGDi S000004486. RPS17A.

    Phylogenomic databases

    eggNOGi COG1383.
    GeneTreei ENSGT00390000006548.
    HOGENOMi HOG000227166.
    KOi K02962.
    OMAi NKVAGFS.
    OrthoDBi EOG7G4QT6.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32626-MONOMER.
    Reactomei REACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Miscellaneous databases

    NextBioi 978109.

    Gene expression databases

    Genevestigatori P02407.

    Family and domain databases

    Gene3Di 1.10.60.20. 1 hit.
    HAMAPi MF_00511. Ribosomal_S17e.
    InterProi IPR001210. Ribosomal_S17e.
    IPR018273. Ribosomal_S17e_CS.
    [Graphical view ]
    PANTHERi PTHR10732. PTHR10732. 1 hit.
    Pfami PF00833. Ribosomal_S17e. 1 hit.
    [Graphical view ]
    SUPFAMi SSF116820. SSF116820. 1 hit.
    PROSITEi PS00712. RIBOSOMAL_S17E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of a beta-galactosidase gene containing the ribosomal protein 51 intron is sensitive to the rna2 mutation of yeast."
      Teem J.L., Rosbash M.
      Proc. Natl. Acad. Sci. U.S.A. 80:4403-4407(1983) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: RY26.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
      Planta R.J., Mager W.H.
      Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE, SUBUNIT.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiRS17A_YEAST
    AccessioniPrimary (citable) accession number: P02407
    Secondary accession number(s): D6VZF0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 121 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 30900 molecules/cell in log phase SD medium.1 Publication
    There are 2 genes for S17 in yeast.

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families
    4. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    5. Yeast chromosome XIII
      Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

    External Data

    Dasty 3