40S ribosomal protein S17-A - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

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P02407 (RS17A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 112. History...

Clusters with 100%, 90%, 50% identity |

Documents (5) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
40S ribosomal protein S17-A

Alternative name(s):
RP51A

Gene names

Name:	RPS17A
Synonyms:	RP51A
Ordered Locus Names:	YML024W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.4
Subcellular location	Cytoplasm Ref.5.
Miscellaneous	Present with 30900 molecules/cell in log phase SD medium. HAMAP-Rule MF_00511 There are 2 genes for S17 in yeast. HAMAP-Rule MF_00511
Sequence similarities	Belongs to the ribosomal protein S17e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Phosphoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cytoplasmic translation Non-traceable author statement Ref.4. Source: SGD ribosomal small subunit assembly Inferred from mutant phenotype PubMed 3915776. Source: SGD translational elongation Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular_component	cytosolic small ribosomal subunit Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	structural constituent of ribosome Non-traceable author statement Ref.4. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 136

136

40S ribosomal protein S17-A HAMAP-Rule MF_00511

PRO_0000141546

Amino acid modifications

Modified residue

Phosphoserine Ref.7 Ref.8

Modified residue

125

Phosphoserine Ref.7

Secondary structure

136

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P02407 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 956E5382870EA289
Show »

FASTA

136

15,788

        10         20         30         40         50         60 
MGRVRTKTVK RASKALIERY YPKLTLDFQT NKRLCDEIAT IQSKRLRNKI AGYTTHLMKR 

        70         80         90        100        110        120 
IQKGPVRGIS FKLQEEERER KDQYVPEVSA LDLSRSNGVL NVDNQTSDLV KSLGLKLPLS 

       130 
VINVSAQRDR RYRKRV

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Expression of a beta-galactosidase gene containing the ribosomal protein 51 intron is sensitive to the rna2 mutation of yeast." Teem J.L., Rosbash M. Proc. Natl. Acad. Sci. U.S.A. 80:4403-4407(1983) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: RY26.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. Barrell B.G. Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]	"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway." Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N. Mol. Cell. Proteomics 4:310-327(2005) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-70 AND SER-125, MASS SPECTROMETRY. Strain: YAL6B.
[8]	"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry." Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-70, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

J01349 Genomic DNA. Translation: AAA88733.1.
Z46659 Genomic DNA. Translation: CAA86631.1.
BK006946 Genomic DNA. Translation: DAA09874.1.

PIR

R5BY51. A02784.

RefSeq

NP_013688.1. NM_001182382.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IZB	electron microscopy	-	Q	1-136	[»]
3O2Z	X-ray	4.00	K	1-136	[»]
3O30	X-ray	4.00	K	1-136	[»]
3U5C	X-ray	3.00	R	1-136	[»]
3U5G	X-ray	3.00	R	1-136	[»]

ProteinModelPortal

P02407.

SMR

P02407. Positions 2-122.

ModBase

Search...

Protein-protein interaction databases

IntAct

P02407. 58 interactions.

MINT

MINT-1324048.

STRING

4932.YML024W.

Proteomic databases

PaxDb

P02407.

PRIDE

P02407.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblFungi

YML024W; YML024W; YML024W.

GeneID

854984.

KEGG

sce:YML024W.

Organism-specific databases

CYGD

YML024w.

SGD

S000004486. RPS17A.

Phylogenomic databases

eggNOG

COG1383.

GeneTree

ENSGT00390000006548.

HOGENOM

HOG000227166.

K02962.

OMA

XDFGSLS.

OrthoDB

EOG40W003.

Gene expression databases

Genevestigator

P02407.

GermOnline

YML024W. Saccharomyces cerevisiae.

Family and domain databases

Gene3D

1.10.60.20. 1 hit.

HAMAP

MF_00511. Ribosomal_S17e.

InterPro

IPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
[Graphical view]

PANTHER

PTHR10732. PTHR10732. 1 hit.

Pfam

PF00833. Ribosomal_S17e. 1 hit.
[Graphical view]

SUPFAM

SSF116820. SSF116820. 1 hit.

PROSITE

PS00712. RIBOSOMAL_S17E. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

NextBio

978109.

Entry information

Entry name

RS17A_YEAST

Accession

Primary (citable) accession number: P02407
Secondary accession number(s): D6VZF0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	April 3, 2013
This is version 112 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Amino acid modifications

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information

Relevant documents