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Protein

40S ribosomal protein S17-A

Gene

RPS17A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • ribosomal small subunit assembly Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-32626-MONOMER.
ReactomeiREACT_290856. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_302067. L13a-mediated translational silencing of Ceruloplasmin expression.
REACT_307259. Formation of a pool of free 40S subunits.
REACT_314339. SRP-dependent cotranslational protein targeting to membrane.
REACT_332565. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_335938. Ribosomal scanning and start codon recognition.
REACT_343353. Peptide chain elongation.
REACT_346847. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_351622. Formation of the ternary complex, and subsequently, the 43S complex.

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S17-A
Alternative name(s):
RP51A
Gene namesi
Name:RPS17A
Synonyms:RP51A
Ordered Locus Names:YML024W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome XIII

Organism-specific databases

CYGDiYML024w.
EuPathDBiFungiDB:YML024W.
SGDiS000004486. RPS17A.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13613640S ribosomal protein S17-APRO_0000141546Add
BLAST

Proteomic databases

PaxDbiP02407.
PRIDEiP02407.

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

Protein-protein interaction databases

BioGridi35145. 72 interactions.
IntActiP02407. 62 interactions.
MINTiMINT-8285645.

Structurei

Secondary structure

1
136
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 1913Combined sources
Helixi21 – 233Combined sources
Helixi28 – 3811Combined sources
Beta strandi39 – 424Combined sources
Helixi44 – 6118Combined sources
Beta strandi62 – 643Combined sources
Helixi73 – 808Combined sources
Beta strandi97 – 993Combined sources
Helixi104 – 11310Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10171-136[»]
3J6Yelectron microscopy6.10171-136[»]
3J77electron microscopy6.20171-136[»]
3J78electron microscopy6.30171-136[»]
3V88X-ray3.00R1-136[»]
4U3MX-ray3.00C7/c71-136[»]
4U3NX-ray3.20C7/c71-136[»]
4U3UX-ray2.90C7/c71-136[»]
4U4NX-ray3.10C7/c71-136[»]
4U4OX-ray3.60C7/c71-136[»]
4U4QX-ray3.00C7/c71-136[»]
4U4RX-ray2.80C7/c71-136[»]
4U4UX-ray3.00C7/c71-136[»]
4U4YX-ray3.20C7/c71-136[»]
4U4ZX-ray3.10C7/c71-136[»]
4U50X-ray3.20C7/c71-136[»]
4U51X-ray3.20C7/c71-136[»]
4U52X-ray3.00C7/c71-136[»]
4U53X-ray3.30C7/c71-136[»]
4U55X-ray3.20C7/c71-136[»]
4U56X-ray3.45C7/c71-136[»]
4U6FX-ray3.10C7/c71-136[»]
4V6Ielectron microscopy8.80AQ1-136[»]
4V7RX-ray4.00AK/CK1-136[»]
4V88X-ray3.00AR/CR1-136[»]
4V8Yelectron microscopy4.30AR1-136[»]
4V8Zelectron microscopy6.60AR1-136[»]
4V92electron microscopy3.70R2-125[»]
ProteinModelPortaliP02407.
SMRiP02407. Positions 2-126.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S17e family.Curated

Phylogenomic databases

eggNOGiCOG1383.
GeneTreeiENSGT00390000006548.
HOGENOMiHOG000227166.
InParanoidiP02407.
KOiK02962.
OMAiDSDTNDM.
OrthoDBiEOG7G4QT6.

Family and domain databases

Gene3Di1.10.60.20. 1 hit.
HAMAPiMF_00511. Ribosomal_S17e.
InterProiIPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
[Graphical view]
PANTHERiPTHR10732. PTHR10732. 1 hit.
PfamiPF00833. Ribosomal_S17e. 1 hit.
[Graphical view]
SUPFAMiSSF116820. SSF116820. 1 hit.
PROSITEiPS00712. RIBOSOMAL_S17E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P02407-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRVRTKTVK RASKALIERY YPKLTLDFQT NKRLCDEIAT IQSKRLRNKI
60 70 80 90 100
AGYTTHLMKR IQKGPVRGIS FKLQEEERER KDQYVPEVSA LDLSRSNGVL
110 120 130
NVDNQTSDLV KSLGLKLPLS VINVSAQRDR RYRKRV
Length:136
Mass (Da):15,788
Last modified:July 21, 1986 - v1
Checksum:i956E5382870EA289
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01349 Genomic DNA. Translation: AAA88733.1.
Z46659 Genomic DNA. Translation: CAA86631.1.
BK006946 Genomic DNA. Translation: DAA09874.1.
PIRiA02784. R5BY51.
RefSeqiNP_013688.1. NM_001182382.1.

Genome annotation databases

EnsemblFungiiYML024W; YML024W; YML024W.
GeneIDi854984.
KEGGisce:YML024W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01349 Genomic DNA. Translation: AAA88733.1.
Z46659 Genomic DNA. Translation: CAA86631.1.
BK006946 Genomic DNA. Translation: DAA09874.1.
PIRiA02784. R5BY51.
RefSeqiNP_013688.1. NM_001182382.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10171-136[»]
3J6Yelectron microscopy6.10171-136[»]
3J77electron microscopy6.20171-136[»]
3J78electron microscopy6.30171-136[»]
3V88X-ray3.00R1-136[»]
4U3MX-ray3.00C7/c71-136[»]
4U3NX-ray3.20C7/c71-136[»]
4U3UX-ray2.90C7/c71-136[»]
4U4NX-ray3.10C7/c71-136[»]
4U4OX-ray3.60C7/c71-136[»]
4U4QX-ray3.00C7/c71-136[»]
4U4RX-ray2.80C7/c71-136[»]
4U4UX-ray3.00C7/c71-136[»]
4U4YX-ray3.20C7/c71-136[»]
4U4ZX-ray3.10C7/c71-136[»]
4U50X-ray3.20C7/c71-136[»]
4U51X-ray3.20C7/c71-136[»]
4U52X-ray3.00C7/c71-136[»]
4U53X-ray3.30C7/c71-136[»]
4U55X-ray3.20C7/c71-136[»]
4U56X-ray3.45C7/c71-136[»]
4U6FX-ray3.10C7/c71-136[»]
4V6Ielectron microscopy8.80AQ1-136[»]
4V7RX-ray4.00AK/CK1-136[»]
4V88X-ray3.00AR/CR1-136[»]
4V8Yelectron microscopy4.30AR1-136[»]
4V8Zelectron microscopy6.60AR1-136[»]
4V92electron microscopy3.70R2-125[»]
ProteinModelPortaliP02407.
SMRiP02407. Positions 2-126.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35145. 72 interactions.
IntActiP02407. 62 interactions.
MINTiMINT-8285645.

Proteomic databases

PaxDbiP02407.
PRIDEiP02407.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYML024W; YML024W; YML024W.
GeneIDi854984.
KEGGisce:YML024W.

Organism-specific databases

CYGDiYML024w.
EuPathDBiFungiDB:YML024W.
SGDiS000004486. RPS17A.

Phylogenomic databases

eggNOGiCOG1383.
GeneTreeiENSGT00390000006548.
HOGENOMiHOG000227166.
InParanoidiP02407.
KOiK02962.
OMAiDSDTNDM.
OrthoDBiEOG7G4QT6.

Enzyme and pathway databases

BioCyciYEAST:G3O-32626-MONOMER.
ReactomeiREACT_290856. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_302067. L13a-mediated translational silencing of Ceruloplasmin expression.
REACT_307259. Formation of a pool of free 40S subunits.
REACT_314339. SRP-dependent cotranslational protein targeting to membrane.
REACT_332565. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_335938. Ribosomal scanning and start codon recognition.
REACT_343353. Peptide chain elongation.
REACT_346847. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_351622. Formation of the ternary complex, and subsequently, the 43S complex.

Miscellaneous databases

NextBioi978109.
PROiP02407.

Family and domain databases

Gene3Di1.10.60.20. 1 hit.
HAMAPiMF_00511. Ribosomal_S17e.
InterProiIPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
[Graphical view]
PANTHERiPTHR10732. PTHR10732. 1 hit.
PfamiPF00833. Ribosomal_S17e. 1 hit.
[Graphical view]
SUPFAMiSSF116820. SSF116820. 1 hit.
PROSITEiPS00712. RIBOSOMAL_S17E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Expression of a beta-galactosidase gene containing the ribosomal protein 51 intron is sensitive to the rna2 mutation of yeast."
    Teem J.L., Rosbash M.
    Proc. Natl. Acad. Sci. U.S.A. 80:4403-4407(1983) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: RY26.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
    Planta R.J., Mager W.H.
    Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE, SUBUNIT.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRS17A_YEAST
AccessioniPrimary (citable) accession number: P02407
Secondary accession number(s): D6VZF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: July 22, 2015
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 30900 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for S17 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.