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Protein

Leghemoglobin-2

Gene
N/A
Organism
Lupinus luteus (European yellow lupine)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi64Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi98Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processNitrogen fixation, Oxygen transport, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Leghemoglobin-2
Alternative name(s):
Leghemoglobin II
OrganismiLupinus luteus (European yellow lupine)
Taxonomic identifieri3873 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeGenisteaeLupinus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001929852 – 154Leghemoglobin-2Add BLAST153

Expressioni

Tissue specificityi

Root nodules.

Interactioni

Subunit structurei

Monomer.

Structurei

Secondary structure

1154
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 20Combined sources15
Helixi23 – 37Combined sources15
Helixi39 – 44Combined sources6
Turni46 – 50Combined sources5
Helixi59 – 82Combined sources24
Helixi89 – 101Combined sources13
Helixi105 – 107Combined sources3
Helixi108 – 123Combined sources16
Helixi124 – 126Combined sources3
Helixi129 – 153Combined sources25

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GDIX-ray1.80A2-154[»]
1GDJX-ray1.70A2-154[»]
1GDKX-ray1.80A2-154[»]
1GDLX-ray1.80A2-154[»]
1LH1X-ray2.00A2-154[»]
1LH2X-ray2.00A2-154[»]
1LH3X-ray2.00A2-154[»]
1LH5X-ray2.00A2-154[»]
1LH6X-ray2.00A2-154[»]
1LH7X-ray2.00A2-154[»]
2GDMX-ray1.70A2-154[»]
2LH1X-ray2.00A2-154[»]
2LH2X-ray2.00A2-154[»]
2LH3X-ray2.00A2-154[»]
2LH5X-ray2.00A2-154[»]
2LH6X-ray2.00A2-154[»]
2LH7X-ray2.00A2-154[»]
ProteinModelPortaliP02240
SMRiP02240
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02240

Family & Domainsi

Sequence similaritiesi

Belongs to the plant globin family.Curated

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR001032 Leghaemoglobin
IPR019824 Leghaemoglobin_Fe_BS
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00188 PLANTGLOBIN
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit
PS00208 PLANT_GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02240-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGALTESQAA LVKSSWEEFN ANIPKHTHRF FILVLEIAPA AKDLFSFLKG
60 70 80 90 100
TSEVPQNNPE LQAHAGKVFK LVYEAAIQLQ VTGVVVTDAT LKNLGSVHVS
110 120 130 140 150
KGVADAHFPV VKEAILKTIK EVVGAKWSEE LNSAWTIAYD ELAIVIKKEM

NDAA
Length:154
Mass (Da):16,783
Last modified:January 23, 2007 - v2
Checksum:i57091640CBAEAF81
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti62Q → AS in AAA33410 (PubMed:2442601).Curated1
Sequence conflicti80Q → E AA sequence (Ref. 1) Curated1
Sequence conflicti87T → S AA sequence (Ref. 1) Curated1
Sequence conflicti151N → D AA sequence (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17893 mRNA Translation: AAA33410.1
PIRiS41328 GPYL2

Similar proteinsi

Entry informationi

Entry nameiLGB2_LUPLU
AccessioniPrimary (citable) accession number: P02240
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 109 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing
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Main funding by: National Institutes of Health