Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Globin, major monomeric component

Gene
N/A
Organism
Glycera dibranchiata (Bloodworm)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi90 – 901Iron (heme axial ligand)
Sitei105 – 1051Causes a bend in the G helix

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Globin, major monomeric component
OrganismiGlycera dibranchiata (Bloodworm)
Taxonomic identifieri6350 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataAciculataPhyllodocidaGlyceridaeGlycera

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 147147Globin, major monomeric componentPRO_0000052500Add
BLAST

Interactioni

Subunit structurei

Monomer.

Structurei

Secondary structure

1
147
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi4 – 1815Combined sources
Turni19 – 235Combined sources
Helixi24 – 3714Combined sources
Helixi39 – 413Combined sources
Turni42 – 465Combined sources
Helixi53 – 7119Combined sources
Turni72 – 743Combined sources
Helixi76 – 8914Combined sources
Helixi90 – 923Combined sources
Beta strandi94 – 963Combined sources
Helixi100 – 1023Combined sources
Helixi103 – 11816Combined sources
Helixi119 – 1213Combined sources
Helixi124 – 14522Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1HBGX-ray1.50A1-147[»]
1JF3X-ray1.40A1-147[»]
1JL7X-ray1.40A1-147[»]
2HBGX-ray1.50A1-147[»]
ProteinModelPortaliP02216.
SMRiP02216. Positions 1-147.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02216.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P02216-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GLSAAQRQVI AATWKDIAGA DNGAGVGKDC LIKFLSAHPQ MAAVFGFSGA
60 70 80 90 100
SDPGVAALGA KVLAQIGVAV SHLGDEGKMV AQMKAVGVRH KGYGNKHIKA
110 120 130 140
QYFEPLGASL LSAMEHRIGG KMNAAAKDAW AAAYADISGA LISGLQS
Length:147
Mass (Da):14,902
Last modified:January 1, 1990 - v2
Checksum:i980558C06D881C43
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti20 – 201A → N AA sequence (PubMed:5063466).Curated
Sequence conflicti34 – 341F → H AA sequence (PubMed:5063466).Curated
Sequence conflicti54 – 541G → A AA sequence (PubMed:5063466).Curated
Sequence conflicti57 – 571A → D AA sequence (PubMed:5063466).Curated
Sequence conflicti100 – 1001A → G AA sequence (PubMed:5063466).Curated

Sequence databases

PIRiA02538. GGNW1B.

Cross-referencesi

Sequence databases

PIRiA02538. GGNW1B.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1HBGX-ray1.50A1-147[»]
1JF3X-ray1.40A1-147[»]
1JL7X-ray1.40A1-147[»]
2HBGX-ray1.50A1-147[»]
ProteinModelPortaliP02216.
SMRiP02216. Positions 1-147.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP02216.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLB1_GLYDI
AccessioniPrimary (citable) accession number: P02216
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 1, 1990
Last modified: November 11, 2015
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Miscellaneous

X-ray crystallographic analysis indicates that the D helix is absent, Leu-58 replaces the distal His (of myoglobin E7), His-90 binds covalently to the heme iron, the F helix has several more residues than in mammalian globins, and Pro-105 (G7) causes a bend in the G helix.

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.