Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Globin, major monomeric component

Gene
N/A
Organism
Glycera dibranchiata (Bloodworm)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

X-ray crystallographic analysis indicates that the D helix is absent, Leu-58 replaces the distal His (of myoglobin E7), His-90 binds covalently to the heme iron, the F helix has several more residues than in mammalian globins, and Pro-105 (G7) causes a bend in the G helix.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi90Iron (heme axial ligand)1
Sitei105Causes a bend in the G helix1

GO - Molecular functioni

Keywordsi

Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Globin, major monomeric component
OrganismiGlycera dibranchiata (Bloodworm)
Taxonomic identifieri6350 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataAciculataPhyllodocidaGlyceridaeGlycera

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000525001 – 147Globin, major monomeric componentAdd BLAST147

Interactioni

Subunit structurei

Monomer.

Structurei

Secondary structure

1147
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 18Combined sources15
Turni19 – 23Combined sources5
Helixi24 – 37Combined sources14
Helixi39 – 41Combined sources3
Turni42 – 46Combined sources5
Helixi53 – 71Combined sources19
Turni72 – 74Combined sources3
Helixi76 – 89Combined sources14
Helixi90 – 92Combined sources3
Beta strandi94 – 96Combined sources3
Helixi100 – 102Combined sources3
Helixi103 – 118Combined sources16
Helixi119 – 121Combined sources3
Helixi124 – 145Combined sources22

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1HBGX-ray1.50A1-147[»]
1JF3X-ray1.40A1-147[»]
1JL7X-ray1.40A1-147[»]
2HBGX-ray1.50A1-147[»]
ProteinModelPortaliP02216
SMRiP02216
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02216

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
PfamiView protein in Pfam
PF00042 Globin, 1 hit
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

P02216-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GLSAAQRQVI AATWKDIAGA DNGAGVGKDC LIKFLSAHPQ MAAVFGFSGA
60 70 80 90 100
SDPGVAALGA KVLAQIGVAV SHLGDEGKMV AQMKAVGVRH KGYGNKHIKA
110 120 130 140
QYFEPLGASL LSAMEHRIGG KMNAAAKDAW AAAYADISGA LISGLQS
Length:147
Mass (Da):14,902
Last modified:January 1, 1990 - v2
Checksum:i980558C06D881C43
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti20A → N AA sequence (PubMed:5063466).Curated1
Sequence conflicti34F → H AA sequence (PubMed:5063466).Curated1
Sequence conflicti54G → A AA sequence (PubMed:5063466).Curated1
Sequence conflicti57A → D AA sequence (PubMed:5063466).Curated1
Sequence conflicti100A → G AA sequence (PubMed:5063466).Curated1

Sequence databases

PIRiA02538 GGNW1B

Similar proteinsi

Entry informationi

Entry nameiGLB1_GLYDI
AccessioniPrimary (citable) accession number: P02216
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 1, 1990
Last modified: April 25, 2018
This is version 92 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health