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Protein

Myoglobin

Gene

MB

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi65Iron (heme distal ligand)1
Metal bindingi94Iron (heme proximal ligand)1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMuscle protein
Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-GGA-8981607. Intracellular oxygen transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000533562 – 154MyoglobinAdd BLAST153

Proteomic databases

PaxDbiP02197.
PRIDEiP02197.

Expressioni

Gene expression databases

BgeeiENSGALG00000012541.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000020457.

Structurei

3D structure databases

ProteinModelPortaliP02197.
SMRiP02197.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00730000110844.
HOGENOMiHOG000070111.
HOVERGENiHBG107340.
InParanoidiP02197.
OMAiLFRNDIA.
OrthoDBiEOG091G0OAO.
PhylomeDBiP02197.
TreeFamiTF332967.

Family and domain databases

InterProiView protein in InterPro
IPR000971. Globin.
IPR009050. Globin-like.
IPR002335. Myoglobin.
PANTHERiPTHR11442:SF57. PTHR11442:SF57. 1 hit.
PfamiView protein in Pfam
PF00042. Globin. 1 hit.
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiView protein in PROSITE
PS01033. GLOBIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02197-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDQEWQQ VLTIWGKVEA DIAGHGHEVL MRLFHDHPET LDRFDKFKGL
60 70 80 90 100
KTPDQMKGSE DLKKHGATVL TQLGKILKQK GNHESELKPL AQTHATKHKI
110 120 130 140 150
PVKYLEFISE VIIKVIAEKH AADFGADSQA AMKKALELFR NDMASKYKEF

GFQG
Length:154
Mass (Da):17,422
Last modified:January 23, 2007 - v4
Checksum:iAE8AEA7C9E83BCD5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti54 – 55DQ → NE (PubMed:6838896).Curated2
Sequence conflicti82N → Q (PubMed:6838896).Curated1
Sequence conflicti86E → D (PubMed:6838896).Curated1

Sequence databases

PIRiA60792. MYCH.
RefSeqiNP_001161224.1. NM_001167752.2.
UniGeneiGga.1960.

Genome annotation databases

EnsembliENSGALT00000020484; ENSGALP00000020457; ENSGALG00000012541.
GeneIDi418056.
KEGGigga:418056.

Similar proteinsi

Entry informationi

Entry nameiMYG_CHICK
AccessioniPrimary (citable) accession number: P02197
Secondary accession number(s): P02198
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: September 27, 2017
This is version 118 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families