Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Myoglobin

Gene

MB

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi65 – 651Iron (heme distal ligand)
Metal bindingi94 – 941Iron (heme proximal ligand)

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 154153MyoglobinPRO_0000053356Add
BLAST

Proteomic databases

PaxDbiP02197.
PRIDEiP02197.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000020457.

Structurei

3D structure databases

ProteinModelPortaliP02197.
SMRiP02197. Positions 2-154.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00730000110844.
HOGENOMiHOG000070111.
HOVERGENiHBG107340.
InParanoidiP02197.
OMAiKKKGQHE.
OrthoDBiEOG7KSX9V.
PhylomeDBiP02197.
TreeFamiTF332967.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02197-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDQEWQQ VLTIWGKVEA DIAGHGHEVL MRLFHDHPET LDRFDKFKGL
60 70 80 90 100
KTPDQMKGSE DLKKHGATVL TQLGKILKQK GNHESELKPL AQTHATKHKI
110 120 130 140 150
PVKYLEFISE VIIKVIAEKH AADFGADSQA AMKKALELFR NDMASKYKEF

GFQG
Length:154
Mass (Da):17,422
Last modified:January 23, 2007 - v4
Checksum:iAE8AEA7C9E83BCD5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti54 – 552DQ → NE (PubMed:6838896).Curated
Sequence conflicti82 – 821N → Q (PubMed:6838896).Curated
Sequence conflicti86 – 861E → D (PubMed:6838896).Curated

Sequence databases

PIRiA60792. MYCH.
RefSeqiNP_001161224.1. NM_001167752.2.
UniGeneiGga.1960.

Genome annotation databases

EnsembliENSGALT00000020484; ENSGALP00000020457; ENSGALG00000012541.
GeneIDi418056.
KEGGigga:418056.

Cross-referencesi

Sequence databases

PIRiA60792. MYCH.
RefSeqiNP_001161224.1. NM_001167752.2.
UniGeneiGga.1960.

3D structure databases

ProteinModelPortaliP02197.
SMRiP02197. Positions 2-154.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000020457.

Proteomic databases

PaxDbiP02197.
PRIDEiP02197.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000020484; ENSGALP00000020457; ENSGALG00000012541.
GeneIDi418056.
KEGGigga:418056.

Organism-specific databases

CTDi4151.

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00730000110844.
HOGENOMiHOG000070111.
HOVERGENiHBG107340.
InParanoidiP02197.
OMAiKKKGQHE.
OrthoDBiEOG7KSX9V.
PhylomeDBiP02197.
TreeFamiTF332967.

Miscellaneous databases

PROiP02197.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Stability properties of oxymyoglobin from chicken gizzard smooth muscle."
    Matsuoka A., Iwaasa H., Takiguchi K., Arakawa N., Li L., Takagi T., Shikama K.
    Comp. Biochem. Physiol. 88B:783-789(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-154.
  2. "The primary sequence of chicken myoglobin (Gallus gallus)."
    Deconinck M., Peiffer S., Depreter J., Paul C., Schnek A.G., Leonis J.
    Biochim. Biophys. Acta 386:567-575(1975) [PubMed] [Europe PMC] [Abstract]
    Cited for: PRELIMINARY PROTEIN SEQUENCE OF 2-154.
  3. Cited for: SEQUENCE REVISION.
    Tissue: Heart muscle.

Entry informationi

Entry nameiMYG_CHICK
AccessioniPrimary (citable) accession number: P02197
Secondary accession number(s): P02198
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: June 8, 2016
This is version 110 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.