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Protein

Myoglobin

Gene

MB

Organism
Ovis aries (Sheep)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi65Iron (heme distal ligand)1
Metal bindingi94Iron (heme proximal ligand)1

GO - Molecular functioni

Keywordsi

Molecular functionMuscle protein
Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiOvis aries (Sheep)
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis
Proteomesi
  • UP000002356 Componenti: Chromosome 3

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000533442 – 154MyoglobinAdd BLAST153

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei4PhosphoserineBy similarity1
Modified residuei68PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliP02190
SMRiP02190
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00730000110844
HOVERGENiHBG107340
KOiK21892
OMAiLFRNDIA
OrthoDBiEOG091G0OAO

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002335 Myoglobin
PANTHERiPTHR11442:SF5 PTHR11442:SF5, 1 hit
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00613 MYOGLOBIN
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02190-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDGEWQL VLNAWGKVEA DVAGHGQEVL IRLFTGHPET LEKFDKFKHL
60 70 80 90 100
KTEAEMKASE DLKKHGNTVL TALGGILKKK GHHEAEVKHL AESHANKHKI
110 120 130 140 150
PVKYLEFISD AIIHVLHAKH PSDFGADAQG AMSKALELFR NDMAAQYKVL

GFQG
Length:154
Mass (Da):17,055
Last modified:January 23, 2007 - v2
Checksum:iE13E47B6C6851761
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti21D → G in ABJ97274 (Ref. 1) Curated1
Sequence conflicti78K → E in ABJ97274 (Ref. 1) Curated1
Sequence conflicti123D → N AA sequence (PubMed:5065743).Curated1
Sequence conflicti146Q → E AA sequence (PubMed:5065743).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ995220 mRNA Translation: ABJ97274.1
PIRiA91195 MYSH
RefSeqiNP_001072126.1, NM_001078658.1
XP_012015345.1, XM_012159955.2
UniGeneiOar.5169

Genome annotation databases

EnsembliENSOART00000020291; ENSOARP00000020014; ENSOARG00000018639
GeneIDi780509
KEGGioas:780509

Similar proteinsi

Entry informationi

Entry nameiMYG_SHEEP
AccessioniPrimary (citable) accession number: P02190
Secondary accession number(s): A0FH33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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