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Protein

Myoglobin

Gene

MB

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi65Iron (heme distal ligand)1 Publication1
Metal bindingi94Iron (heme proximal ligand)Combined sources2 Publications1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000533362 – 154MyoglobinAdd BLAST153

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei4PhosphoserineBy similarity1
Modified residuei68PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PeptideAtlasiP02189.
PRIDEiP02189.

Structurei

Secondary structure

1154
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 19Combined sources15
Helixi22 – 36Combined sources15
Helixi38 – 41Combined sources4
Helixi45 – 47Combined sources3
Helixi53 – 58Combined sources6
Helixi60 – 77Combined sources18
Turni78 – 81Combined sources4
Helixi84 – 95Combined sources12
Turni96 – 98Combined sources3
Helixi102 – 119Combined sources18
Turni121 – 123Combined sources3
Helixi126 – 149Combined sources24

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1M6CX-ray1.90A/B2-154[»]
1M6MX-ray1.80A/B2-154[»]
1MDNX-ray1.98A/B2-154[»]
1MNHX-ray2.30A2-154[»]
1MNIX-ray2.07A/B2-154[»]
1MNJX-ray2.20A/B2-154[»]
1MNKX-ray2.20A/B2-154[»]
1MNOX-ray1.95A/B2-154[»]
1MWCX-ray1.70A/B2-154[»]
1MWDX-ray1.80A/B2-154[»]
1MYGX-ray1.75A/B2-154[»]
1MYHX-ray1.90A/B2-154[»]
1MYIX-ray2.00A/B2-154[»]
1MYJX-ray1.90A/B2-154[»]
1PMBX-ray2.50A/B2-154[»]
1YCAX-ray2.90A/B2-154[»]
1YCBX-ray2.10A/B2-154[»]
ProteinModelPortaliP02189.
SMRiP02189.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02189.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG107340.
InParanoidiP02189.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02189-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDGEWQL VLNVWGKVEA DVAGHGQEVL IRLFKGHPET LEKFDKFKHL
60 70 80 90 100
KSEDEMKASE DLKKHGNTVL TALGGILKKK GHHEAELTPL AQSHATKHKI
110 120 130 140 150
PVKYLEFISE AIIQVLQSKH PGDFGADAQG AMSKALELFR NDMAAKYKEL

GFQG
Length:154
Mass (Da):17,085
Last modified:January 23, 2007 - v2
Checksum:i1CF92ACD400A76D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14433 mRNA. Translation: AAA31073.1.
PIRiA23988. MYPG.
RefSeqiNP_999401.1. NM_214236.1.
UniGeneiSsc.715.

Genome annotation databases

GeneIDi397467.
KEGGissc:397467.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14433 mRNA. Translation: AAA31073.1.
PIRiA23988. MYPG.
RefSeqiNP_999401.1. NM_214236.1.
UniGeneiSsc.715.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1M6CX-ray1.90A/B2-154[»]
1M6MX-ray1.80A/B2-154[»]
1MDNX-ray1.98A/B2-154[»]
1MNHX-ray2.30A2-154[»]
1MNIX-ray2.07A/B2-154[»]
1MNJX-ray2.20A/B2-154[»]
1MNKX-ray2.20A/B2-154[»]
1MNOX-ray1.95A/B2-154[»]
1MWCX-ray1.70A/B2-154[»]
1MWDX-ray1.80A/B2-154[»]
1MYGX-ray1.75A/B2-154[»]
1MYHX-ray1.90A/B2-154[»]
1MYIX-ray2.00A/B2-154[»]
1MYJX-ray1.90A/B2-154[»]
1PMBX-ray2.50A/B2-154[»]
1YCAX-ray2.90A/B2-154[»]
1YCBX-ray2.10A/B2-154[»]
ProteinModelPortaliP02189.
SMRiP02189.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiP02189.
PRIDEiP02189.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi397467.
KEGGissc:397467.

Organism-specific databases

CTDi4151.

Phylogenomic databases

HOVERGENiHBG107340.
InParanoidiP02189.

Miscellaneous databases

EvolutionaryTraceiP02189.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMYG_PIG
AccessioniPrimary (citable) accession number: P02189
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.