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Protein

Myoglobin

Gene

MB

Organism
Elephas maximus (Indian elephant)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi94Iron (heme proximal ligand)Combined sources1 Publication1

GO - Molecular functioni

Keywordsi

Molecular functionMuscle protein
Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiElephas maximus (Indian elephant)
Taxonomic identifieri9783 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaAfrotheriaProboscideaElephantidaeElephas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000532902 – 154MyoglobinAdd BLAST153

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei4PhosphoserineBy similarity1
Modified residuei68PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Structurei

Secondary structure

1154
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 19Combined sources15
Helixi22 – 36Combined sources15
Helixi38 – 43Combined sources6
Turni45 – 49Combined sources5
Helixi53 – 57Combined sources5
Helixi60 – 78Combined sources19
Turni79 – 81Combined sources3
Helixi84 – 96Combined sources13
Helixi102 – 119Combined sources18
Turni121 – 123Combined sources3
Helixi126 – 149Combined sources24

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EMYX-ray1.78A2-154[»]
ProteinModelPortaliP02186
SMRiP02186
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02186

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG107340

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002335 Myoglobin
PANTHERiPTHR11442:SF5 PTHR11442:SF5, 1 hit
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00613 MYOGLOBIN
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02186-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDGEWEL VLKTWGKVEA DIPGHGETVF VRLFTGHPET LEKFDKFKHL
60 70 80 90 100
KTEGEMKASE DLKKQGVTVL TALGGILKKK GHHEAEIQPL AQSHATKHKI
110 120 130 140 150
PIKYLEFISD AIIHVLQSKH PAEFGADAQG AMKKALELFR NDIAAKYKEL

GFQG
Length:154
Mass (Da):17,127
Last modified:January 23, 2007 - v3
Checksum:iF1031658D39BEAD5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti28T → F AA sequence (PubMed:6102395).Curated1
Sequence conflicti30F → L AA sequence (PubMed:6102395).Curated1

Sequence databases

PIRiA94228 MYELI

Similar proteinsi

Entry informationi

Entry nameiMYG_ELEMA
AccessioniPrimary (citable) accession number: P02186
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 98 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health