##gff-version 3
P01920	UniProtKB	Signal peptide	1	32	.	.	.	Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:6576979;Dbxref=PMID:6576979	
P01920	UniProtKB	Chain	33	261	.	.	.	ID=PRO_0000018989;Note=HLA class II histocompatibility antigen%2C DQ beta 1 chain	
P01920	UniProtKB	Topological domain	33	230	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P01920	UniProtKB	Transmembrane	231	251	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P01920	UniProtKB	Topological domain	252	261	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P01920	UniProtKB	Domain	129	217	.	.	.	Note=Ig-like C1-type	
P01920	UniProtKB	Region	33	126	.	.	.	Note=Beta-1	
P01920	UniProtKB	Region	127	220	.	.	.	Note=Beta-2	
P01920	UniProtKB	Region	221	230	.	.	.	Note=Connecting peptide	
P01920	UniProtKB	Glycosylation	51	51	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P01920	UniProtKB	Disulfide bond	47	111	.	.	.	.	
P01920	UniProtKB	Disulfide bond	149	205	.	.	.	.	
P01920	UniProtKB	Natural variant	6	6	.	.	.	ID=VAR_056570;Note=In allele DQB1*05:01 and allele DQB1*05:02. A->S;Dbxref=dbSNP:rs1049056	
P01920	UniProtKB	Natural variant	12	12	.	.	.	ID=VAR_062679;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*06:02 and allele DQB1*06:12. G->D;Dbxref=dbSNP:rs1049057	
P01920	UniProtKB	Natural variant	15	15	.	.	.	ID=VAR_062680;Note=In allele DQB1*03:02%2C allele DQB1*03:03%2C allele DQB1*04:01%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*06:02 and allele DQB1*06:12. A->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:3584986;Dbxref=dbSNP:rs3189152,PMID:3584986	
P01920	UniProtKB	Natural variant	23	23	.	.	.	ID=VAR_062681;Note=In allele DQB1*02:01 and allele DQB1*02:02. A->S;Dbxref=dbSNP:rs3891176	
P01920	UniProtKB	Natural variant	24	24	.	.	.	ID=VAR_062682;Note=In allele DQB1*05:01 and allele DQB1*05:02. M->I;Dbxref=dbSNP:rs1049059	
P01920	UniProtKB	Natural variant	27	27	.	.	.	ID=VAR_062683;Note=In allele DQB1*04:01. T->A;Dbxref=dbSNP:rs1049060	
P01920	UniProtKB	Natural variant	27	27	.	.	.	ID=VAR_062684;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*06:02 and allele DQB1*06:12. T->S;Dbxref=dbSNP:rs1049060	
P01920	UniProtKB	Natural variant	28	28	.	.	.	ID=VAR_062685;Note=In allele DQB1*06:02 and allele DQB1*06:12. P->L;Dbxref=dbSNP:rs1049062	
P01920	UniProtKB	Natural variant	28	28	.	.	.	ID=VAR_062686;Note=In allele DQB1*05:01 and allele DQB1*05:02. P->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:3584986;Dbxref=dbSNP:rs1049061,PMID:3584986	
P01920	UniProtKB	Natural variant	29	29	.	.	.	ID=VAR_062687;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*06:02 and allele DQB1*06:12. V->L;Dbxref=dbSNP:rs1130366	
P01920	UniProtKB	Natural variant	35	35	.	.	.	ID=VAR_062688;Note=In allele DQB1*06:01. S->P;Dbxref=dbSNP:rs12722106	
P01920	UniProtKB	Natural variant	41	41	.	.	.	ID=VAR_062689;Note=In allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*06:02%2C allele DQB1*06:10%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:29%2C allele DQB1*06:33 and allele DQB1*06:37. Y->F;Dbxref=dbSNP:rs9274407	
P01920	UniProtKB	Natural variant	41	41	.	.	.	ID=VAR_062690;Note=In allele DQB1*06:01 and allele DQB1*06:35%3B requires 2 nucleotide substitutions. Y->L	
P01920	UniProtKB	Natural variant	43	43	.	.	.	ID=VAR_062691;Note=In allele DQB1*06:33. F->L;Dbxref=dbSNP:rs56173496	
P01920	UniProtKB	Natural variant	45	45	.	.	.	ID=VAR_061472;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*03:02%2C allele DQB1*03:03%2C allele DQB1*03:05%2C allele DQB1*03:06%2C allele DQB1*03:07%2C allele DQB1*03:08%2C allele DQB1*03:11%2C allele DQB1*03:15%2C allele DQB1*03:17%2C allele DQB1*03:18%2C allele DQB1*03:20%2C allele DQB1*03:23%2C allele DQB1*03:25%2C allele DQB1*03:26%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39. A->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:3584986;Dbxref=dbSNP:rs1130375,PMID:3584986	
P01920	UniProtKB	Natural variant	46	46	.	.	.	ID=VAR_061473;Note=In allele DQB1*03:11%2C allele DQB1*03:26%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05%2C allele DQB1*06:05%2C allele DQB1*06:20 and allele DQB1*06:31. M->L;Dbxref=dbSNP:rs1130368	
P01920	UniProtKB	Natural variant	55	55	.	.	.	ID=VAR_062692;Note=In allele DQB1*04:01. R->L;Dbxref=dbSNP:rs41540813	
P01920	UniProtKB	Natural variant	58	58	.	.	.	ID=VAR_062693;Note=In allele DQB1*03:05%2C allele DQB1*03:17%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05 and allele DQB1*06:23%3B requires 2 nucleotide substitutions. Y->G	
P01920	UniProtKB	Natural variant	58	58	.	.	.	ID=VAR_062694;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*03:02%2C allele DQB1*03:03%2C allele DQB1*03:06%2C allele DQB1*03:07%2C allele DQB1*03:08%2C allele DQB1*03:11%2C allele DQB1*03:12%2C allele DQB1*03:15%2C allele DQB1*03:18%2C allele DQB1*03:20%2C allele DQB1*03:23%2C allele DQB1*03:25%2C allele DQB1*03:26%2C allele DQB1*04:03%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:06%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39%3B requires 2 nucleotide substitutions. Y->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:3584986;Dbxref=dbSNP:rs766817072,PMID:3584986	
P01920	UniProtKB	Natural variant	59	59	.	.	.	ID=VAR_062695;Note=In allele DQB1*03:18. V->L;Dbxref=dbSNP:rs41563539	
P01920	UniProtKB	Natural variant	60	60	.	.	.	ID=VAR_062696;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05. T->S;Dbxref=dbSNP:rs9274405	
P01920	UniProtKB	Natural variant	62	62	.	.	.	ID=VAR_062697;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:14%2C allele DQB1*06:17%2C allele DQB1*06:21%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39. Y->H;Dbxref=dbSNP:rs281862065	
P01920	UniProtKB	Natural variant	62	62	.	.	.	ID=VAR_062698;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05. Y->S	
P01920	UniProtKB	Natural variant	69	69	.	.	.	ID=VAR_062699;Note=In allele DQB1*06:01 and allele DQB1*06:35. Y->D;Dbxref=dbSNP:rs281874782	
P01920	UniProtKB	Natural variant	69	69	.	.	.	ID=VAR_062700;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05%3B requires 2 nucleotide substitutions. Y->I	
P01920	UniProtKB	Natural variant	70	70	.	.	.	ID=VAR_062701;Note=In allele DQB1*03:20. A->T;Dbxref=dbSNP:rs45519640	
P01920	UniProtKB	Natural variant	70	70	.	.	.	ID=VAR_062702;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*06:01%2C allele DQB1*06:28 and allele DQB1*06:35. A->V;Dbxref=dbSNP:rs1063318	
P01920	UniProtKB	Natural variant	77	77	.	.	.	ID=VAR_062703;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*03:02%2C allele DQB1*03:03%2C allele DQB1*03:05%2C allele DQB1*03:06%2C allele DQB1*03:07%2C allele DQB1*03:08%2C allele DQB1*03:10%2C allele DQB1*03:11%2C allele DQB1*03:12%2C allele DQB1*03:14%2C allele DQB1*03:15%2C allele DQB1*03:17%2C allele DQB1*03:18%2C allele DQB1*03:20%2C allele DQB1*03:23%2C allele DQB1*03:25%2C allele DQB1*03:26%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:06%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39. E->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:3584986;Dbxref=dbSNP:rs1049083,PMID:3584986	
P01920	UniProtKB	Natural variant	78	78	.	.	.	ID=VAR_062704;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05. V->E;Dbxref=dbSNP:rs9274398	
P01920	UniProtKB	Natural variant	79	79	.	.	.	ID=VAR_062705;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05. Y->F;Dbxref=dbSNP:rs9274397	
P01920	UniProtKB	Natural variant	81	81	.	.	.	ID=VAR_062706;Note=In allele DQB1*03:07. A->V;Dbxref=dbSNP:rs41558214	
P01920	UniProtKB	Natural variant	84	84	.	.	.	ID=VAR_062707;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05. P->L;Dbxref=dbSNP:rs9274395	
P01920	UniProtKB	Natural variant	85	85	.	.	.	ID=VAR_062708;Note=In allele DQB1*03:23%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:06%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:20%2C allele DQB1*06:22%2C allele DQB1*06:21%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39. L->Q;Dbxref=dbSNP:rs1140313	
P01920	UniProtKB	Natural variant	87	87	.	.	.	ID=VAR_062709;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05. P->L;Dbxref=dbSNP:rs1130380	
P01920	UniProtKB	Natural variant	87	87	.	.	.	ID=VAR_062710;Note=In allele DQB1*03:16. P->Q;Dbxref=dbSNP:rs1130380	
P01920	UniProtKB	Natural variant	87	87	.	.	.	ID=VAR_062711;Note=In allele DQB1*03:23%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:06%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:35%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39. P->R;Dbxref=dbSNP:rs1130380	
P01920	UniProtKB	Natural variant	88	88	.	.	.	ID=VAR_062712;Note=In allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02 and allele DQB1*04:03. P->L;Dbxref=dbSNP:rs1130381	
P01920	UniProtKB	Natural variant	89	89	.	.	.	ID=VAR_062713;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*03:02%2C allele DQB1*03:04%2C allele DQB1*03:05%2C allele DQB1*03:07%2C allele DQB1*03:08%2C allele DQB1*03:11%2C allele DQB1*03:14%2C allele DQB1*03:18 and allele DQB1*06:29. D->A;Dbxref=dbSNP:rs1071637	
P01920	UniProtKB	Natural variant	89	89	.	.	.	ID=VAR_062714;Note=In allele DQB1*05:02%2C allele DQB1*05:04%2C allele DQB1*05:05%2C allele DQB1*06:10 and allele DQB1*06:25%3B requires 2 nucleotide substitutions. D->S	
P01920	UniProtKB	Natural variant	89	89	.	.	.	ID=VAR_062715;Note=In allele DQB1*05:01%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:06%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:27%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39. D->V;Dbxref=dbSNP:rs1071637	
P01920	UniProtKB	Natural variant	92	92	.	.	.	ID=VAR_062716;Note=In allele DQB1*06:16. Y->N;Dbxref=dbSNP:rs41562414	
P01920	UniProtKB	Natural variant	94	94	.	.	.	ID=VAR_062717;Note=In allele DQB1*06:37. N->K;Dbxref=dbSNP:rs1130382	
P01920	UniProtKB	Natural variant	95	95	.	.	.	ID=VAR_062718;Note=In allele DQB1*03:15. S->R;Dbxref=dbSNP:rs41556215	
P01920	UniProtKB	Natural variant	98	98	.	.	.	ID=VAR_062719;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*03:06%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*05:04%2C allele DQB1*06:01 and allele DQB1*06:35. E->D;Dbxref=dbSNP:rs9274390	
P01920	UniProtKB	Natural variant	99	99	.	.	.	ID=VAR_062720;Note=In allele DQB1*03:13. V->D;Dbxref=dbSNP:rs41563814	
P01920	UniProtKB	Natural variant	99	99	.	.	.	ID=VAR_062721;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*03:06%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*05:04%2C allele DQB1*06:01 and allele DQB1*06:35. V->I;Dbxref=dbSNP:rs9274390	
P01920	UniProtKB	Natural variant	102	102	.	.	.	ID=VAR_062722;Note=In allele DQB1*03:06%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03 and allele DQB1*05:04%3B requires 2 nucleotide substitutions. R->E	
P01920	UniProtKB	Natural variant	102	102	.	.	.	ID=VAR_062723;Note=In allele DQB1*03:08%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:08%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:21%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31 and allele DQB1*06:33. R->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:3584986;Dbxref=dbSNP:rs1130386,PMID:3584986	
P01920	UniProtKB	Natural variant	103	103	.	.	.	ID=VAR_062724;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:17%2C allele DQB1*06:24 and allele DQB1*06:30. T->A;Dbxref=dbSNP:rs1130390	
P01920	UniProtKB	Natural variant	103	103	.	.	.	ID=VAR_062725;Note=In allele DQB1*03:06%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03 and allele DQB1*05:04%3B requires 2 nucleotide substitutions. T->D	
P01920	UniProtKB	Natural variant	103	103	.	.	.	ID=VAR_062726;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04 and allele DQB1*02:05. T->K	
P01920	UniProtKB	Natural variant	106	106	.	.	.	ID=VAR_062727;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05 and allele DQB1*06:06. E->A;Dbxref=dbSNP:rs1130387	
P01920	UniProtKB	Natural variant	106	106	.	.	.	ID=VAR_062728;Note=In allele DQB1*03:06%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04 and allele DQB1*05:05%3B requires 2 nucleotide substitutions. E->S	
P01920	UniProtKB	Natural variant	107	107	.	.	.	ID=VAR_062729;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*02:05%2C allele DQB1*03:06%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*04:03%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05 and allele DQB1*06:06. L->V;Dbxref=dbSNP:rs9274384	
P01920	UniProtKB	Natural variant	109	109	.	.	.	ID=VAR_062730;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:03%2C allele DQB1*02:04%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:04%2C allele DQB1*05:05 and allele DQB1*06:06. T->R;Dbxref=dbSNP:rs1130392	
P01920	UniProtKB	Natural variant	116	116	.	.	.	ID=VAR_062731;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:35%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38%2C allele DQB1*06:39. Q->E;Dbxref=dbSNP:rs1140316	
P01920	UniProtKB	Natural variant	117	117	.	.	.	ID=VAR_062732;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:35%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39. L->V;Dbxref=dbSNP:rs1140317	
P01920	UniProtKB	Natural variant	118	118	.	.	.	ID=VAR_062733;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:08%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:16%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:35 and allele DQB1*06:37. E->A;Dbxref=dbSNP:rs9274380	
P01920	UniProtKB	Natural variant	118	118	.	.	.	ID=VAR_062734;Note=In allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:07%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:15%2C allele DQB1*06:17%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:25%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39. E->G;Dbxref=dbSNP:rs9274380	
P01920	UniProtKB	Natural variant	119	119	.	.	.	ID=VAR_062735;Note=In allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:08%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:16%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:20%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:35 and allele DQB1*06:37. L->F;Dbxref=dbSNP:rs9274379	
P01920	UniProtKB	Natural variant	119	119	.	.	.	ID=VAR_062736;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:07%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:15%2C allele DQB1*06:17%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:25%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39%3B requires 2 nucleotide substitutions. L->Y	
P01920	UniProtKB	Natural variant	121	121	.	.	.	ID=VAR_062737;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:13%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:35%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39%3B requires 2 nucleotide substitutions. T->G	
P01920	UniProtKB	Natural variant	122	122	.	.	.	ID=VAR_062738;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*05:05%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:05%2C allele DQB1*06:07%2C allele DQB1*06:08%2C allele DQB1*06:09%2C allele DQB1*06:10%2C allele DQB1*06:11%2C allele DQB1*06:12%2C allele DQB1*06:14%2C allele DQB1*06:15%2C allele DQB1*06:16%2C allele DQB1*06:17%2C allele DQB1*06:18%2C allele DQB1*06:19%2C allele DQB1*06:21%2C allele DQB1*06:22%2C allele DQB1*06:23%2C allele DQB1*06:24%2C allele DQB1*06:25%2C allele DQB1*06:27%2C allele DQB1*06:28%2C allele DQB1*06:29%2C allele DQB1*06:30%2C allele DQB1*06:31%2C allele DQB1*06:32%2C allele DQB1*06:33%2C allele DQB1*06:34%2C allele DQB1*06:35%2C allele DQB1*06:36%2C allele DQB1*06:37%2C allele DQB1*06:38 and allele DQB1*06:39. T->I;Dbxref=dbSNP:rs1140320	
P01920	UniProtKB	Natural variant	148	148	.	.	.	ID=VAR_056571;Note=In allele DQB1*05:01%2C allele DQB1*05:02 and allele DQB1*05:03. V->I;Dbxref=dbSNP:rs1049100	
P01920	UniProtKB	Natural variant	157	157	.	.	.	ID=VAR_062739;Note=In allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39. A->G;Dbxref=dbSNP:rs1063322	
P01920	UniProtKB	Natural variant	157	157	.	.	.	ID=VAR_062740;Note=In allele DQB1*05:01%2C allele DQB1*05:02 and allele DQB1*05:03. A->S	
P01920	UniProtKB	Natural variant	158	158	.	.	.	ID=VAR_062741;Note=In allele DQB1*05:02. Q->H;Dbxref=dbSNP:rs41542812	
P01920	UniProtKB	Natural variant	162	162	.	.	.	ID=VAR_062742;Note=In allele DQB1*03:22%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:34%2C allele DQB1*06:36 and allele DQB1*06:38. R->Q;Dbxref=dbSNP:rs41544112	
P01920	UniProtKB	Natural variant	165	165	.	.	.	ID=VAR_062744;Note=In allele DQB1*06:38. R->Q;Dbxref=dbSNP:rs9273989	
P01920	UniProtKB	Natural variant	165	165	.	.	.	ID=VAR_062743;Note=In allele DQB1*03:21. R->W;Dbxref=dbSNP:rs63626961	
P01920	UniProtKB	Natural variant	167	167	.	.	.	ID=VAR_062745;Note=In allele DQB1*02:02. D->G;Dbxref=dbSNP:rs2647032	
P01920	UniProtKB	Natural variant	168	168	.	.	.	ID=VAR_062746;Note=In allele DQB1*02:04. Q->E;Dbxref=dbSNP:rs9273981	
P01920	UniProtKB	Natural variant	172	172	.	.	.	ID=VAR_062747;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:04%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39. T->A;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21269460;Dbxref=dbSNP:rs1063323,PMID:21269460	
P01920	UniProtKB	Natural variant	194	194	.	.	.	ID=VAR_056572;Note=E->D;Dbxref=dbSNP:rs9273952	
P01920	UniProtKB	Natural variant	197	197	.	.	.	ID=VAR_059522;Note=P->L;Dbxref=dbSNP:rs9273948	
P01920	UniProtKB	Natural variant	199	199	.	.	.	ID=VAR_062748;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:04%2C allele DQB1*03:02%2C allele DQB1*03:03%2C allele DQB1*03:05%2C allele DQB1*03:23%2C allele DQB1*03:25%2C allele DQB1*04:01%2C allele DQB1*04:02%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39. H->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:3584986;Dbxref=dbSNP:rs701564,PMID:3584986	
P01920	UniProtKB	Natural variant	200	201	.	.	.	ID=VAR_062749;Note=In allele DQB1*03:09. GD->A	
P01920	UniProtKB	Natural variant	202	202	.	.	.	ID=VAR_062750;Note=In allele DQB1*03:24. V->I;Dbxref=dbSNP:rs80255621	
P01920	UniProtKB	Natural variant	214	214	.	.	.	ID=VAR_062751;Note=In allele DQB1*02:01%2C allele DQB1*02:02%2C allele DQB1*02:04%2C allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12%2C allele DQB1*06:34%2C allele DQB1*06:36%2C allele DQB1*06:38 and allele DQB1*06:39. N->S;Dbxref=dbSNP:rs1130398	
P01920	UniProtKB	Natural variant	217	217	.	.	.	ID=VAR_062752;Note=In allele DQB1*03:02%2C allele DQB1*03:03%2C allele DQB1*03:05%2C allele DQB1*03:19%2C allele DQB1*03:25%2C allele DQB1*04:01 and allele DQB1*04:02. T->I;Dbxref=dbSNP:rs1130399	
P01920	UniProtKB	Natural variant	218	218	.	.	.	ID=VAR_062753;Note=In allele DQB1*06:36. V->A;Dbxref=dbSNP:rs281864132	
P01920	UniProtKB	Natural variant	229	229	.	.	.	ID=VAR_062754;Note=In allele DQB1*06:01. S->N;Dbxref=dbSNP:rs1130429	
P01920	UniProtKB	Natural variant	235	235	.	.	.	ID=VAR_062755;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12 and allele DQB1*06:36. I->V;Dbxref=dbSNP:rs1049163	
P01920	UniProtKB	Natural variant	252	252	.	.	.	ID=VAR_062756;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12 and allele DQB1*06:36. H->R;Dbxref=dbSNP:rs1140342	
P01920	UniProtKB	Natural variant	253	253	.	.	.	ID=VAR_062757;Note=In allele DQB1*05:01%2C allele DQB1*05:02%2C allele DQB1*05:03%2C allele DQB1*06:01%2C allele DQB1*06:02%2C allele DQB1*06:03%2C allele DQB1*06:04%2C allele DQB1*06:09%2C allele DQB1*06:12 and allele DQB1*06:36. H->Q;Dbxref=dbSNP:rs1140343	
P01920	UniProtKB	Natural variant	256	256	.	.	.	ID=VAR_061474;Note=In allele DQB1*05:01%2C allele DQB1*05:02 and allele DQB1*05:03. Q->R;Dbxref=dbSNP:rs1130432	
P01920	UniProtKB	Sequence conflict	111	111	.	.	.	Note=C->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P01920	UniProtKB	Sequence conflict	113	113	.	.	.	Note=H->Q;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P01920	UniProtKB	Sequence conflict	173	173	.	.	.	Note=G->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P01920	UniProtKB	Sequence conflict	214	214	.	.	.	Note=N->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P01920	UniProtKB	Beta strand	40	50	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Turn	51	54	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	55	64	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	67	73	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Turn	74	76	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	78	83	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Helix	84	86	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Helix	87	94	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Helix	97	109	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Helix	111	117	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Helix	119	122	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	130	135	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	141	144	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1JK8	
P01920	UniProtKB	Beta strand	146	157	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	160	165	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	168	170	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	174	176	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	183	185	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	187	194	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	203	208	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ	
P01920	UniProtKB	Beta strand	216	220	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1UVQ