Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-2-microglobulin

Gene

B2m

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Immunity

Enzyme and pathway databases

ReactomeiR-GGA-1236974. ER-Phagosome pathway.
R-MMU-1236974. ER-Phagosome pathway.
R-MMU-1236977. Endosomal/Vacuolar pathway.
R-MMU-198933. Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
R-MMU-2172127. DAP12 interactions.
R-MMU-2424491. DAP12 signaling.
R-MMU-983170. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-2-microglobulin
Gene namesi
Name:B2m
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:88127. B2m.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MHC I, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 20202 PublicationsAdd
BLAST
Chaini21 – 11999Beta-2-microglobulinPRO_0000018784Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi45 ↔ 100

Keywords - PTMi

Disulfide bond

Proteomic databases

EPDiP01887.
PaxDbiP01887.
PeptideAtlasiP01887.
PRIDEiP01887.

2D gel databases

SWISS-2DPAGEP01887.

PTM databases

iPTMnetiP01887.
PhosphoSiteiP01887.

Miscellaneous databases

PMAP-CutDBP01887.

Expressioni

Gene expression databases

BgeeiENSMUSG00000060802.
CleanExiMM_B2M.
GenevisibleiP01887. MM.

Interactioni

Subunit structurei

Heterodimer of an alpha chain and a beta chain. Beta-2-microglobulin is the beta-chain of major histocompatibility complex class I molecules.

GO - Molecular functioni

Protein-protein interaction databases

BioGridi198291. 2 interactions.
DIPiDIP-6111N.
IntActiP01887. 5 interactions.
MINTiMINT-1870185.
STRINGi10090.ENSMUSP00000099534.

Structurei

Secondary structure

1
119
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi26 – 338Combined sources
Beta strandi37 – 393Combined sources
Beta strandi41 – 5313Combined sources
Beta strandi56 – 616Combined sources
Beta strandi70 – 767Combined sources
Turni78 – 803Combined sources
Beta strandi82 – 909Combined sources
Beta strandi94 – 963Combined sources
Beta strandi98 – 1036Combined sources
Beta strandi107 – 1093Combined sources
Beta strandi111 – 1144Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1BIIX-ray2.40B1-119[»]
1BQHX-ray2.80B/E21-119[»]
1BZ9X-ray2.80B21-119[»]
1CD1X-ray2.67B/D21-119[»]
1DDHX-ray3.10B22-119[»]
1FFNX-ray2.70B/E21-119[»]
1FFOX-ray2.65B/E21-119[»]
1FFPX-ray2.60B/E21-119[»]
1FG2X-ray2.75B/E/H/K21-119[»]
1FO0X-ray2.50L21-119[»]
1FZJX-ray1.90B21-119[»]
1FZKX-ray1.70B21-119[»]
1FZMX-ray1.80B21-119[»]
1FZOX-ray1.80B21-119[»]
1G6RX-ray2.80L/M21-119[»]
1G7PX-ray1.50B21-119[»]
1G7QX-ray1.60B21-119[»]
1HOCX-ray2.40B21-119[»]
1INQX-ray2.20B21-119[»]
1JPFX-ray2.18B21-119[»]
1JPGX-ray2.20B21-119[»]
1JUFX-ray2.00B21-119[»]
1K8DX-ray2.30B21-119[»]
1KBGX-ray2.20L21-119[»]
1KJ2X-ray2.71L/M21-119[»]
1KJ3X-ray2.30L/M21-119[»]
1KPUX-ray1.50B21-119[»]
1KPVX-ray1.71B21-119[»]
1L6Qmodel-B21-119[»]
1LD9X-ray2.40B/E21-119[»]
1LDPX-ray3.10L21-119[»]
1LEGX-ray1.75B21-119[»]
1LEKX-ray2.15B21-119[»]
1LK2X-ray1.35B21-119[»]
1MHCX-ray2.10B/E21-119[»]
1MWAX-ray2.40L/M21-119[»]
1N3NX-ray3.00B/D/F/H21-119[»]
1N59X-ray2.95B/D21-119[»]
1N5AX-ray2.85B/E/H/K21-119[»]
1NAMX-ray2.70L21-119[»]
1NANX-ray2.30I/P21-119[»]
1NEZX-ray2.10B21-119[»]
1OSZX-ray2.10B21-119[»]
1P1ZX-ray3.26B21-119[»]
1P4LX-ray2.90B21-119[»]
1PQZX-ray2.10B21-119[»]
1QO3X-ray2.30B21-119[»]
1RJYX-ray1.90B/E21-119[»]
1RJZX-ray2.60B/E21-119[»]
1RK0X-ray2.61B21-119[»]
1RK1X-ray2.10B21-119[»]
1S7QX-ray1.99B21-119[»]
1S7RX-ray2.95B/E21-119[»]
1S7SX-ray1.99B21-119[»]
1S7TX-ray2.30B/E21-119[»]
1S7UX-ray2.20B/E/H/K21-119[»]
1S7VX-ray2.20B/E21-119[»]
1S7WX-ray2.40B/E/H/K21-119[»]
1S7XX-ray2.41B/E/H/K21-119[»]
1T0MX-ray2.00B/E21-119[»]
1T0NX-ray1.80B/E21-119[»]
1U58X-ray1.90B21-119[»]
1VACX-ray2.50B21-119[»]
1VADX-ray2.50B21-119[»]
1WBXX-ray1.90B21-119[»]
1WBYX-ray2.30B21-119[»]
1WBZX-ray2.00B/D21-119[»]
1YN6X-ray2.20B21-119[»]
1YN7X-ray2.20B21-119[»]
1Z5LX-ray2.20B/D21-119[»]
1ZHBX-ray2.70B/E/H/K21-119[»]
1ZHNX-ray2.80B21-119[»]
1ZT1X-ray2.50B21-119[»]
1ZT7X-ray3.00B/D21-119[»]
2AKRX-ray1.90B/D21-119[»]
2CKBX-ray3.00L/M21-119[»]
2CLVX-ray1.90B/P21-119[»]
2CLZX-ray1.90B/P21-119[»]
2FIKX-ray1.80B21-119[»]
2FO4X-ray2.70B21-119[»]
2FWOX-ray2.60B21-119[»]
2GAZX-ray2.61B21-119[»]
2MHAX-ray2.50B/D21-119[»]
2OL3X-ray2.90L21-119[»]
2Q7YX-ray1.95B/D21-119[»]
2QRIX-ray2.00A/B21-119[»]
2QRSX-ray2.00A/B21-119[»]
2QRTX-ray1.80A/B21-119[»]
2VAAX-ray2.30B21-119[»]
2VABX-ray2.50B21-119[»]
2VE6X-ray2.65B/E/H/K22-119[»]
2ZOKX-ray2.10B/D/F/H21-119[»]
2ZOLX-ray2.70B/D21-119[»]
2ZSVX-ray1.80B/D21-119[»]
2ZSWX-ray2.80B/D/F/H21-119[»]
3ARBX-ray2.70B21-119[»]
3ARDX-ray3.01B21-119[»]
3AREX-ray2.80B21-119[»]
3ARFX-ray2.90B21-119[»]
3ARGX-ray3.00B21-119[»]
3AU1X-ray2.50B21-119[»]
3BUYX-ray2.60B21-119[»]
3C8KX-ray2.90B21-119[»]
3CC5X-ray1.91B/E21-119[»]
3CCHX-ray2.60B/E/H/K21-119[»]
3CH1X-ray2.30B/E/H/K21-119[»]
3CPLX-ray2.50B/D21-119[»]
3CVHX-ray2.90B/N21-119[»]
3DMMX-ray2.60B21-119[»]
3E6FX-ray2.41B22-119[»]
3E6HX-ray2.10B21-119[»]
3ECBX-ray1.70B21-119[»]
3FOLX-ray2.50B21-119[»]
3FOMX-ray2.10B21-119[»]
3FONX-ray2.03B/D21-119[»]
3FTGX-ray2.60B21-119[»]
3G08X-ray1.60B21-119[»]
3GMLX-ray1.70B21-119[»]
3GMMX-ray1.80B21-119[»]
3GMNX-ray1.70B21-119[»]
3GMOX-ray1.60B21-119[»]
3GMPX-ray1.70B21-119[»]
3GMQX-ray1.80B21-119[»]
3GMRX-ray1.90B21-119[»]
3HE6X-ray2.90B21-119[»]
3HE7X-ray2.80B21-119[»]
3ILPX-ray1.85B21-119[»]
3ILQX-ray2.05D21-119[»]
3L3HX-ray2.70B21-119[»]
3MA7X-ray2.29B/D21-119[»]
3NWMX-ray2.70A21-119[»]
3O8XX-ray2.74B21-119[»]
3O9WX-ray2.80B21-119[»]
3P4MX-ray2.50B/E21-119[»]
3P4NX-ray2.50B/E21-119[»]
3P4OX-ray2.30B/E21-119[»]
3P9LX-ray2.00B/E21-119[»]
3P9MX-ray2.00B/E21-119[»]
3PABX-ray2.20B/E21-119[»]
3PQYX-ray3.19B/G/L/Q21-119[»]
3PWUX-ray1.90B21-119[»]
3QI9X-ray2.30B21-119[»]
3QUKX-ray2.41B/E21-119[»]
3QULX-ray2.00B/E/H/K21-119[»]
3QUXX-ray2.91B21-119[»]
3QUYX-ray2.25B21-119[»]
3QUZX-ray2.30B21-119[»]
3RGVX-ray2.90D21-119[»]
3ROLX-ray2.60B/D21-119[»]
3ROOX-ray2.00B/D21-119[»]
3RTQX-ray2.80B21-119[»]
3RUGX-ray2.20B/D21-119[»]
3RZCX-ray2.80B21-119[»]
3SCMX-ray2.50B21-119[»]
3SDAX-ray2.80B21-119[»]
3SDCX-ray3.10B21-119[»]
3SDDX-ray3.00B21-119[»]
3T1FX-ray1.70B21-119[»]
3TA3X-ray2.70B21-119[»]
3TBSX-ray2.49B/E21-119[»]
3TBTX-ray2.30B/E/H/K21-119[»]
3TBVX-ray2.10B/D/F/H21-119[»]
3TBWX-ray2.15B/D/F/H21-119[»]
3TBYX-ray2.50B/E/H/K21-119[»]
3TN0X-ray3.20B21-119[»]
3TO4X-ray3.10B21-119[»]
3TVMX-ray2.80B/F21-119[»]
3UBXX-ray3.10B/E21-119[»]
3VJ6X-ray1.90B21-119[»]
3WS3X-ray2.34B/D21-119[»]
3WS6X-ray1.98C/D21-119[»]
4APQX-ray3.00B21-119[»]
4EI5X-ray3.10B/F21-119[»]
4ELMX-ray3.48B/D21-119[»]
4HS3X-ray2.10B21-119[»]
4HUUX-ray2.00B/E21-119[»]
4HUVX-ray2.50B/E21-119[»]
4HUWX-ray3.16B/D/F/H21-119[»]
4HUXX-ray2.20B21-119[»]
4HV8X-ray2.00B/D21-119[»]
4IHOX-ray2.80B/E21-119[»]
4IRJX-ray3.00B21-119[»]
4IRSX-ray2.80B21-119[»]
4L8BX-ray2.20B21-119[»]
4L8CX-ray2.80B/D/F/H21-119[»]
4L8DX-ray1.90B/D21-119[»]
4MNGX-ray3.01B/D21-119[»]
4MQ7X-ray2.60B21-119[»]
4MX7X-ray2.24B21-119[»]
4NSKX-ray2.60B21-119[»]
4PG2X-ray2.80C21-119[»]
4PG9X-ray2.40B21-119[»]
4PGBX-ray2.80B/E21-119[»]
4PGCX-ray2.30B/E21-119[»]
4PGDX-ray2.70B21-119[»]
4PGEX-ray2.00B21-119[»]
4PV8X-ray2.31B/D21-119[»]
4PV9X-ray2.00B/D21-119[»]
4Y16X-ray2.60B21-119[»]
4Y2DX-ray3.05B/F21-119[»]
4Y4FX-ray3.19B/F21-119[»]
4Y4HX-ray3.10B/F21-119[»]
4Y4KX-ray2.90B21-119[»]
4ZAKX-ray2.82B21-119[»]
4ZUSX-ray2.60B21-119[»]
4ZUTX-ray2.60B21-119[»]
4ZUUX-ray2.20B21-119[»]
4ZUVX-ray2.30B/E21-119[»]
4ZUWX-ray2.60B21-119[»]
5E8NX-ray2.25B/E/H/K21-119[»]
5E8OX-ray1.98B/E21-119[»]
5E8PX-ray2.00B/E21-119[»]
5EFIX-ray1.80B21-119[»]
5FKPX-ray1.80B21-119[»]
ProteinModelPortaliP01887.
SMRiP01887. Positions 21-119.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01887.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 11490Ig-like C1-typeAdd
BLAST

Sequence similaritiesi

Belongs to the beta-2-microglobulin family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiENOG410J15A. Eukaryota.
ENOG410YTDG. LUCA.
GeneTreeiENSGT00690000102227.
HOGENOMiHOG000043084.
HOVERGENiHBG006197.
InParanoidiP01887.
KOiK08055.
OMAiPNFLNCY.
OrthoDBiEOG091G0ZOW.
TreeFamiTF334167.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR015707. B2Microglobulin.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
[Graphical view]
PANTHERiPTHR19944:SF62. PTHR19944:SF62. 1 hit.
PfamiPF07654. C1-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01887-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARSVTLVFL VLVSLTGLYA IQKTPQIQVY SRHPPENGKP NILNCYVTQF
60 70 80 90 100
HPPHIEIQML KNGKKIPKVE MSDMSFSKDW SFYILAHTEF TPTETDTYAC
110
RVKHASMAEP KTVYWDRDM
Length:119
Mass (Da):13,779
Last modified:October 3, 2012 - v2
Checksum:i94F649EBCF1D7A4E
GO

Polymorphismi

The following alleles of B2M are known: A, B, W2, W3, W4 and W5 (C). The sequence shown is that of allele B.Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti8 – 81V → I in allele W3. 1 Publication
Natural varianti54 – 541H → Q in allele W4. 1 Publication
Natural varianti64 – 641K → E in allele W3. 1 Publication
Natural varianti101 – 1011R → T in allele W2. 1 Publication
Natural varianti105 – 1051A → D in allele A. 6 Publications
Natural varianti105 – 1051A → V in allele W2, W4 and W5. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X01838 mRNA. Translation: CAA25970.1.
M12485 Genomic DNA. No translation available.
M84363 Genomic DNA. Translation: AAA39667.1.
M84364 Genomic DNA. Translation: AAA39668.1.
M84365 Genomic DNA. Translation: AAA39669.1.
M84366 Genomic DNA. Translation: AAA39670.1.
M84367 Genomic DNA. Translation: AAA39671.1.
AK019389 mRNA. Translation: BAB31695.1.
AK028378 mRNA. Translation: BAC25917.1.
AK166067 mRNA. Translation: BAE38551.1.
AL845457 Genomic DNA. Translation: CAM21783.1.
CH466519 Genomic DNA. Translation: EDL28084.1.
BC085164 mRNA. Translation: AAH85164.1.
M10389 mRNA. Translation: AAA39536.1.
M10416 mRNA. Translation: AAA39537.1.
CCDSiCCDS16654.1.
PIRiA90822. MGMSB2.
RefSeqiNP_033865.2. NM_009735.3.
UniGeneiMm.163.

Genome annotation databases

EnsembliENSMUST00000102476; ENSMUSP00000099534; ENSMUSG00000060802.
GeneIDi12010.
KEGGimmu:12010.
UCSCiuc008maf.1. mouse.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X01838 mRNA. Translation: CAA25970.1.
M12485 Genomic DNA. No translation available.
M84363 Genomic DNA. Translation: AAA39667.1.
M84364 Genomic DNA. Translation: AAA39668.1.
M84365 Genomic DNA. Translation: AAA39669.1.
M84366 Genomic DNA. Translation: AAA39670.1.
M84367 Genomic DNA. Translation: AAA39671.1.
AK019389 mRNA. Translation: BAB31695.1.
AK028378 mRNA. Translation: BAC25917.1.
AK166067 mRNA. Translation: BAE38551.1.
AL845457 Genomic DNA. Translation: CAM21783.1.
CH466519 Genomic DNA. Translation: EDL28084.1.
BC085164 mRNA. Translation: AAH85164.1.
M10389 mRNA. Translation: AAA39536.1.
M10416 mRNA. Translation: AAA39537.1.
CCDSiCCDS16654.1.
PIRiA90822. MGMSB2.
RefSeqiNP_033865.2. NM_009735.3.
UniGeneiMm.163.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1BIIX-ray2.40B1-119[»]
1BQHX-ray2.80B/E21-119[»]
1BZ9X-ray2.80B21-119[»]
1CD1X-ray2.67B/D21-119[»]
1DDHX-ray3.10B22-119[»]
1FFNX-ray2.70B/E21-119[»]
1FFOX-ray2.65B/E21-119[»]
1FFPX-ray2.60B/E21-119[»]
1FG2X-ray2.75B/E/H/K21-119[»]
1FO0X-ray2.50L21-119[»]
1FZJX-ray1.90B21-119[»]
1FZKX-ray1.70B21-119[»]
1FZMX-ray1.80B21-119[»]
1FZOX-ray1.80B21-119[»]
1G6RX-ray2.80L/M21-119[»]
1G7PX-ray1.50B21-119[»]
1G7QX-ray1.60B21-119[»]
1HOCX-ray2.40B21-119[»]
1INQX-ray2.20B21-119[»]
1JPFX-ray2.18B21-119[»]
1JPGX-ray2.20B21-119[»]
1JUFX-ray2.00B21-119[»]
1K8DX-ray2.30B21-119[»]
1KBGX-ray2.20L21-119[»]
1KJ2X-ray2.71L/M21-119[»]
1KJ3X-ray2.30L/M21-119[»]
1KPUX-ray1.50B21-119[»]
1KPVX-ray1.71B21-119[»]
1L6Qmodel-B21-119[»]
1LD9X-ray2.40B/E21-119[»]
1LDPX-ray3.10L21-119[»]
1LEGX-ray1.75B21-119[»]
1LEKX-ray2.15B21-119[»]
1LK2X-ray1.35B21-119[»]
1MHCX-ray2.10B/E21-119[»]
1MWAX-ray2.40L/M21-119[»]
1N3NX-ray3.00B/D/F/H21-119[»]
1N59X-ray2.95B/D21-119[»]
1N5AX-ray2.85B/E/H/K21-119[»]
1NAMX-ray2.70L21-119[»]
1NANX-ray2.30I/P21-119[»]
1NEZX-ray2.10B21-119[»]
1OSZX-ray2.10B21-119[»]
1P1ZX-ray3.26B21-119[»]
1P4LX-ray2.90B21-119[»]
1PQZX-ray2.10B21-119[»]
1QO3X-ray2.30B21-119[»]
1RJYX-ray1.90B/E21-119[»]
1RJZX-ray2.60B/E21-119[»]
1RK0X-ray2.61B21-119[»]
1RK1X-ray2.10B21-119[»]
1S7QX-ray1.99B21-119[»]
1S7RX-ray2.95B/E21-119[»]
1S7SX-ray1.99B21-119[»]
1S7TX-ray2.30B/E21-119[»]
1S7UX-ray2.20B/E/H/K21-119[»]
1S7VX-ray2.20B/E21-119[»]
1S7WX-ray2.40B/E/H/K21-119[»]
1S7XX-ray2.41B/E/H/K21-119[»]
1T0MX-ray2.00B/E21-119[»]
1T0NX-ray1.80B/E21-119[»]
1U58X-ray1.90B21-119[»]
1VACX-ray2.50B21-119[»]
1VADX-ray2.50B21-119[»]
1WBXX-ray1.90B21-119[»]
1WBYX-ray2.30B21-119[»]
1WBZX-ray2.00B/D21-119[»]
1YN6X-ray2.20B21-119[»]
1YN7X-ray2.20B21-119[»]
1Z5LX-ray2.20B/D21-119[»]
1ZHBX-ray2.70B/E/H/K21-119[»]
1ZHNX-ray2.80B21-119[»]
1ZT1X-ray2.50B21-119[»]
1ZT7X-ray3.00B/D21-119[»]
2AKRX-ray1.90B/D21-119[»]
2CKBX-ray3.00L/M21-119[»]
2CLVX-ray1.90B/P21-119[»]
2CLZX-ray1.90B/P21-119[»]
2FIKX-ray1.80B21-119[»]
2FO4X-ray2.70B21-119[»]
2FWOX-ray2.60B21-119[»]
2GAZX-ray2.61B21-119[»]
2MHAX-ray2.50B/D21-119[»]
2OL3X-ray2.90L21-119[»]
2Q7YX-ray1.95B/D21-119[»]
2QRIX-ray2.00A/B21-119[»]
2QRSX-ray2.00A/B21-119[»]
2QRTX-ray1.80A/B21-119[»]
2VAAX-ray2.30B21-119[»]
2VABX-ray2.50B21-119[»]
2VE6X-ray2.65B/E/H/K22-119[»]
2ZOKX-ray2.10B/D/F/H21-119[»]
2ZOLX-ray2.70B/D21-119[»]
2ZSVX-ray1.80B/D21-119[»]
2ZSWX-ray2.80B/D/F/H21-119[»]
3ARBX-ray2.70B21-119[»]
3ARDX-ray3.01B21-119[»]
3AREX-ray2.80B21-119[»]
3ARFX-ray2.90B21-119[»]
3ARGX-ray3.00B21-119[»]
3AU1X-ray2.50B21-119[»]
3BUYX-ray2.60B21-119[»]
3C8KX-ray2.90B21-119[»]
3CC5X-ray1.91B/E21-119[»]
3CCHX-ray2.60B/E/H/K21-119[»]
3CH1X-ray2.30B/E/H/K21-119[»]
3CPLX-ray2.50B/D21-119[»]
3CVHX-ray2.90B/N21-119[»]
3DMMX-ray2.60B21-119[»]
3E6FX-ray2.41B22-119[»]
3E6HX-ray2.10B21-119[»]
3ECBX-ray1.70B21-119[»]
3FOLX-ray2.50B21-119[»]
3FOMX-ray2.10B21-119[»]
3FONX-ray2.03B/D21-119[»]
3FTGX-ray2.60B21-119[»]
3G08X-ray1.60B21-119[»]
3GMLX-ray1.70B21-119[»]
3GMMX-ray1.80B21-119[»]
3GMNX-ray1.70B21-119[»]
3GMOX-ray1.60B21-119[»]
3GMPX-ray1.70B21-119[»]
3GMQX-ray1.80B21-119[»]
3GMRX-ray1.90B21-119[»]
3HE6X-ray2.90B21-119[»]
3HE7X-ray2.80B21-119[»]
3ILPX-ray1.85B21-119[»]
3ILQX-ray2.05D21-119[»]
3L3HX-ray2.70B21-119[»]
3MA7X-ray2.29B/D21-119[»]
3NWMX-ray2.70A21-119[»]
3O8XX-ray2.74B21-119[»]
3O9WX-ray2.80B21-119[»]
3P4MX-ray2.50B/E21-119[»]
3P4NX-ray2.50B/E21-119[»]
3P4OX-ray2.30B/E21-119[»]
3P9LX-ray2.00B/E21-119[»]
3P9MX-ray2.00B/E21-119[»]
3PABX-ray2.20B/E21-119[»]
3PQYX-ray3.19B/G/L/Q21-119[»]
3PWUX-ray1.90B21-119[»]
3QI9X-ray2.30B21-119[»]
3QUKX-ray2.41B/E21-119[»]
3QULX-ray2.00B/E/H/K21-119[»]
3QUXX-ray2.91B21-119[»]
3QUYX-ray2.25B21-119[»]
3QUZX-ray2.30B21-119[»]
3RGVX-ray2.90D21-119[»]
3ROLX-ray2.60B/D21-119[»]
3ROOX-ray2.00B/D21-119[»]
3RTQX-ray2.80B21-119[»]
3RUGX-ray2.20B/D21-119[»]
3RZCX-ray2.80B21-119[»]
3SCMX-ray2.50B21-119[»]
3SDAX-ray2.80B21-119[»]
3SDCX-ray3.10B21-119[»]
3SDDX-ray3.00B21-119[»]
3T1FX-ray1.70B21-119[»]
3TA3X-ray2.70B21-119[»]
3TBSX-ray2.49B/E21-119[»]
3TBTX-ray2.30B/E/H/K21-119[»]
3TBVX-ray2.10B/D/F/H21-119[»]
3TBWX-ray2.15B/D/F/H21-119[»]
3TBYX-ray2.50B/E/H/K21-119[»]
3TN0X-ray3.20B21-119[»]
3TO4X-ray3.10B21-119[»]
3TVMX-ray2.80B/F21-119[»]
3UBXX-ray3.10B/E21-119[»]
3VJ6X-ray1.90B21-119[»]
3WS3X-ray2.34B/D21-119[»]
3WS6X-ray1.98C/D21-119[»]
4APQX-ray3.00B21-119[»]
4EI5X-ray3.10B/F21-119[»]
4ELMX-ray3.48B/D21-119[»]
4HS3X-ray2.10B21-119[»]
4HUUX-ray2.00B/E21-119[»]
4HUVX-ray2.50B/E21-119[»]
4HUWX-ray3.16B/D/F/H21-119[»]
4HUXX-ray2.20B21-119[»]
4HV8X-ray2.00B/D21-119[»]
4IHOX-ray2.80B/E21-119[»]
4IRJX-ray3.00B21-119[»]
4IRSX-ray2.80B21-119[»]
4L8BX-ray2.20B21-119[»]
4L8CX-ray2.80B/D/F/H21-119[»]
4L8DX-ray1.90B/D21-119[»]
4MNGX-ray3.01B/D21-119[»]
4MQ7X-ray2.60B21-119[»]
4MX7X-ray2.24B21-119[»]
4NSKX-ray2.60B21-119[»]
4PG2X-ray2.80C21-119[»]
4PG9X-ray2.40B21-119[»]
4PGBX-ray2.80B/E21-119[»]
4PGCX-ray2.30B/E21-119[»]
4PGDX-ray2.70B21-119[»]
4PGEX-ray2.00B21-119[»]
4PV8X-ray2.31B/D21-119[»]
4PV9X-ray2.00B/D21-119[»]
4Y16X-ray2.60B21-119[»]
4Y2DX-ray3.05B/F21-119[»]
4Y4FX-ray3.19B/F21-119[»]
4Y4HX-ray3.10B/F21-119[»]
4Y4KX-ray2.90B21-119[»]
4ZAKX-ray2.82B21-119[»]
4ZUSX-ray2.60B21-119[»]
4ZUTX-ray2.60B21-119[»]
4ZUUX-ray2.20B21-119[»]
4ZUVX-ray2.30B/E21-119[»]
4ZUWX-ray2.60B21-119[»]
5E8NX-ray2.25B/E/H/K21-119[»]
5E8OX-ray1.98B/E21-119[»]
5E8PX-ray2.00B/E21-119[»]
5EFIX-ray1.80B21-119[»]
5FKPX-ray1.80B21-119[»]
ProteinModelPortaliP01887.
SMRiP01887. Positions 21-119.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi198291. 2 interactions.
DIPiDIP-6111N.
IntActiP01887. 5 interactions.
MINTiMINT-1870185.
STRINGi10090.ENSMUSP00000099534.

PTM databases

iPTMnetiP01887.
PhosphoSiteiP01887.

2D gel databases

SWISS-2DPAGEP01887.

Proteomic databases

EPDiP01887.
PaxDbiP01887.
PeptideAtlasiP01887.
PRIDEiP01887.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000102476; ENSMUSP00000099534; ENSMUSG00000060802.
GeneIDi12010.
KEGGimmu:12010.
UCSCiuc008maf.1. mouse.

Organism-specific databases

CTDi567.
MGIiMGI:88127. B2m.

Phylogenomic databases

eggNOGiENOG410J15A. Eukaryota.
ENOG410YTDG. LUCA.
GeneTreeiENSGT00690000102227.
HOGENOMiHOG000043084.
HOVERGENiHBG006197.
InParanoidiP01887.
KOiK08055.
OMAiPNFLNCY.
OrthoDBiEOG091G0ZOW.
TreeFamiTF334167.

Enzyme and pathway databases

ReactomeiR-GGA-1236974. ER-Phagosome pathway.
R-MMU-1236974. ER-Phagosome pathway.
R-MMU-1236977. Endosomal/Vacuolar pathway.
R-MMU-198933. Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
R-MMU-2172127. DAP12 interactions.
R-MMU-2424491. DAP12 signaling.
R-MMU-983170. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Miscellaneous databases

EvolutionaryTraceiP01887.
PMAP-CutDBP01887.
PROiP01887.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000060802.
CleanExiMM_B2M.
GenevisibleiP01887. MM.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR015707. B2Microglobulin.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
[Graphical view]
PANTHERiPTHR19944:SF62. PTHR19944:SF62. 1 hit.
PfamiPF07654. C1-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB2MG_MOUSE
AccessioniPrimary (citable) accession number: P01887
Secondary accession number(s): Q91XJ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: October 3, 2012
Last modified: September 7, 2016
This is version 177 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.