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Protein

Immunoglobulin kappa constant

Gene

Igkc

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Immunoglobulin kappa constantBy similarity
Alternative name(s):
Ig kappa chain C region MOPC 211 Publication
Gene namesi
Name:IgkcImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:96495 Igkc

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000153597‹1 – 107Immunoglobulin kappa constantAdd BLAST›107

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi27 ↔ 87PROSITE-ProRule annotation1 Publication
Disulfide bondi107Interchain (with a heavy chain)PROSITE-ProRule annotation1 Publication

Keywords - PTMi

Disulfide bond

Proteomic databases

EPDiP01837
MaxQBiP01837
PeptideAtlasiP01837
PRIDEiP01837

PTM databases

iPTMnetiP01837

Expressioni

Gene expression databases

BgeeiENSMUSG00000076609

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiP01837, 1 interactor
MINTiP01837

Structurei

Secondary structure

1107
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi7 – 11Combined sources5
Helixi15 – 19Combined sources5
Beta strandi22 – 35Combined sources14
Beta strandi38 – 43Combined sources6
Beta strandi46 – 48Combined sources3
Beta strandi52 – 56Combined sources5
Turni61 – 63Combined sources3
Beta strandi66 – 75Combined sources10
Helixi76 – 79Combined sources4
Beta strandi84 – 90Combined sources7
Beta strandi91 – 96Combined sources6
Beta strandi98 – 103Combined sources6
Helixi104 – 106Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
15C8X-ray2.50L1-105[»]
1A0QX-ray2.30L1-106[»]
1A3LX-ray1.95L1-105[»]
1AHWX-ray3.00A/D1-107[»]
1AI1X-ray2.80L1-104[»]
1AIFX-ray2.90A/L1-107[»]
1C12X-ray2.60A1-106[»]
1CF8X-ray2.70L1-107[»]
1CFNX-ray2.65A1-107[»]
1CFQX-ray2.80A1-107[»]
1CFSX-ray2.75A1-107[»]
1CFTX-ray2.80A1-107[»]
1CICX-ray2.50A1-107[»]
1CK0X-ray2.50L1-104[»]
1CT8X-ray2.20A/C1-107[»]
1DQJX-ray2.00A1-107[»]
1DQMX-ray2.10L1-107[»]
1DQQX-ray1.80A/C1-107[»]
1E4WX-ray1.95L1-107[»]
1E4XX-ray1.90L/M1-107[»]
1EHLX-ray2.40L1-106[»]
1EMTX-ray2.25L1-107[»]
1FAIX-ray2.70L1-107[»]
1FBIX-ray3.00L/P1-107[»]
1FDLX-ray2.50L1-107[»]
1FE8X-ray2.03L/M/N1-104[»]
1FGNX-ray2.50L1-107[»]
1FJ1X-ray2.68A/C1-106[»]
1FL3X-ray2.45B/L1-103[»]
1FNSX-ray2.00L1-107[»]
1FRGX-ray2.80L1-104[»]
1FSKX-ray2.90B/E/H/K1-107[»]
1GPOX-ray1.95L/M1-107[»]
1HH6X-ray2.60A1-107[»]
1HH9X-ray2.70A1-107[»]
1HI6X-ray2.55A1-107[»]
1I8MX-ray2.10A/L1-107[»]
1IAIX-ray2.90M1-107[»]
1IGYX-ray3.20A/C1-107[»]
1JNLX-ray3.00L1-104[»]
1JNNX-ray3.20L1-104[»]
1JRHX-ray2.80L1-107[»]
1K4CX-ray2.00B1-105[»]
1K4DX-ray2.30B1-105[»]
1KB5X-ray2.50L1-107[»]
1KC5X-ray2.50L1-107[»]
1KCRX-ray2.90L1-107[»]
1KCSX-ray2.50L1-107[»]
1KCUX-ray2.20L1-107[»]
1KCVX-ray1.80L1-107[»]
1KENX-ray3.50L/U1-105[»]
1KNOX-ray3.20A/C/E1-107[»]
1LO0X-ray2.00L/X1-107[»]
1MF2X-ray2.60L/M1-104[»]
1MH5X-ray2.10A/L1-107[»]
1MLBX-ray2.10A1-107[»]
1MLCX-ray2.50A/C1-107[»]
1N5YX-ray3.10L1-104[»]
1N6QX-ray3.00L1-104[»]
1NBYX-ray1.80A1-107[»]
1NBZX-ray1.85A1-107[»]
1NDGX-ray1.90A1-107[»]
1NDMX-ray2.10A1-107[»]
1OAKX-ray2.20L1-105[»]
1OB1X-ray2.90A/D1-107[»]
1ORQX-ray3.20A1-107[»]
1ORSX-ray1.90A1-107[»]
1OSPX-ray1.95L1-107[»]
1OTSX-ray2.51D/F1-104[»]
1OTTX-ray3.00D/F1-104[»]
1OTUX-ray3.30D/F1-104[»]
1P2CX-ray2.00A/D1-105[»]
1P7KX-ray1.75A/L1-107[»]
1PSKX-ray2.80L1-107[»]
1Q9OX-ray1.79A/C1-107[»]
1Q9WX-ray1.75A/C1-107[»]
1QGCelectron microscopy30.0041-107[»]
1R0AX-ray2.80L1-104[»]
1R24X-ray3.10A/C1-99[»]
1R3IX-ray2.40L1-105[»]
1R3JX-ray1.90A1-105[»]
1R3KX-ray2.80A1-105[»]
1R3LX-ray2.41A1-105[»]
1RIHX-ray2.50L1-107[»]
1RUQX-ray1.86L1-105[»]
1RURX-ray1.50L1-105[»]
1S5HX-ray2.20A1-105[»]
1SEQX-ray1.78L1-107[»]
1T03X-ray3.10L1-104[»]
1T4KX-ray2.50C1-105[»]
1UB5X-ray2.00B/L1-102[»]
1UB6X-ray2.12B/L1-102[»]
1UWXX-ray2.20K/L1-106[»]
1XF2X-ray2.30A/L1-107[»]
1XF3X-ray2.30A/L1-107[»]
1XF4X-ray2.50A/L1-107[»]
1XGPX-ray2.10A1-107[»]
1XGQX-ray2.10A1-107[»]
1XGUX-ray2.10A1-107[»]
25C8X-ray2.00L1-104[»]
2A6DX-ray2.90L1-107[»]
2A6KX-ray3.00A/L1-107[»]
2ADFX-ray1.90L1-103[»]
2ADJX-ray2.90A1-107[»]
2AJSX-ray1.70L1-104[»]
2AJUX-ray1.50L1-104[»]
2AJVX-ray1.50L1-104[»]
2AJXX-ray1.85L1-104[»]
2AJYX-ray2.10L1-104[»]
2AJZX-ray2.30A/L1-104[»]
2AK1X-ray1.85L1-104[»]
2BOBX-ray2.76B1-105[»]
2BOCX-ray3.01B1-105[»]
2CK0X-ray2.20L1-104[»]
2F19X-ray2.80L1-107[»]
2FR4X-ray1.95A1-107[»]
2G5BX-ray2.30C/E/G1-105[»]
2H8PX-ray2.25B1-105[»]
2HG5X-ray2.75B1-105[»]
2HRPX-ray2.20L/M1-107[»]
2MPAX-ray2.60L9-13[»]
2NR6X-ray2.81C/E1-104[»]
2Q76X-ray2.00A/C1-105[»]
2R1WX-ray1.70A1-107[»]
2R1YX-ray1.60A1-107[»]
2R23X-ray1.65A1-107[»]
2R2BX-ray1.60A1-107[»]
2UYLX-ray2.50A/M/V/X1-107[»]
2V17X-ray1.65L1-107[»]
2V7HX-ray2.80A/L1-107[»]
2VC2X-ray3.10L1-107[»]
2VDKX-ray2.80L1-107[»]
2VDLX-ray2.75L1-107[»]
2VDMX-ray2.90L1-107[»]
2VDNX-ray2.90L1-107[»]
2VDOX-ray2.51L1-107[»]
2VDPX-ray2.80L1-107[»]
2VDQX-ray2.59L1-107[»]
2VDRX-ray2.40L1-107[»]
2VL5X-ray2.10B/D1-107[»]
2VQ1X-ray2.50A/E1-105[»]
2VWEX-ray3.40C/J1-107[»]
2W60X-ray1.50B1-105[»]
2W65X-ray2.21B/D1-105[»]
2W9DX-ray1.57L1-106[»]
2W9EX-ray2.90L1-106[»]
2Z91X-ray2.60B/D1-107[»]
2Z92X-ray2.30B1-107[»]
2Z93X-ray2.40B/D1-107[»]
2ZJSX-ray3.20L1-107[»]
35C8X-ray2.00L1-104[»]
3BAEX-ray1.59L1-106[»]
3BGFX-ray3.00C/L1-105[»]
3BKCX-ray1.90L1-107[»]
3BKJX-ray1.59L1-107[»]
3BKMX-ray1.60L1-107[»]
3BPCX-ray1.85A1-107[»]
3BQUX-ray3.00C1-104[»]
3BSZX-ray3.38L/M1-104[»]
3BT2X-ray2.50L1-107[»]
3BZ4X-ray1.80A/C/E/G1-107[»]
3C5SX-ray2.00A/C1-107[»]
3C6SX-ray1.80A/C/E/G1-107[»]
3CFBX-ray1.60A/L1-107[»]
3CFCX-ray1.70L1-107[»]
3CFDX-ray2.50A/L1-107[»]
3CFEX-ray2.99A/L1-107[»]
3CK0X-ray3.00L1-104[»]
3CLEX-ray2.50L1-107[»]
3CLFX-ray2.00L1-107[»]
3CMOX-ray2.30L/X1-104[»]
3CVHX-ray2.90L/R1-103[»]
3CVIX-ray1.80L1-103[»]
3D9AX-ray1.20L1-106[»]
3EJZX-ray2.90D/F1-104[»]
3EOTX-ray1.90L1-107[»]
3F7VX-ray3.20B1-105[»]
3F7YX-ray3.40B1-105[»]
3FB6X-ray3.00B1-105[»]
3HFMX-ray3.00L1-107[»]
4KK5X-ray3.17D/F1-104[»]
4KK8X-ray2.86D/F1-104[»]
4KVCX-ray2.31L1-105[»]
4QNPX-ray2.80F/L1-106[»]
4ZXBX-ray3.30B1-107[»]
6FABX-ray1.90L1-107[»]
ProteinModelPortaliP01837
SMRiP01837
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01837

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 103Ig-likePROSITE-ProRule annotationAdd BLAST98

Keywords - Domaini

Immunoglobulin C region, Immunoglobulin domain

Phylogenomic databases

HOVERGENiHBG039526
InParanoidiP01837
OMAiHKVYACE
PhylomeDBiP01837

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Complete.

P01837-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RADAAPTVSI FPPSSEQLTS GGASVVCFLN NFYPKDINVK WKIDGSERQN
60 70 80 90 100
GVLNSWTDQD SKDSTYSMSS TLTLTKDEYE RHNSYTCEAT HKTSTSPIVK

SFNRNEC
Length:107
Mass (Da):11,934
Last modified:February 28, 2018 - v2
Checksum:iA3B25CFA8D7C30CC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00807 Genomic DNA Translation: CAA24189.1
AC153612 Genomic DNA No translation available.
PIRiB90262 K1MS
UniGeneiMm.333124

Similar proteinsi

Entry informationi

Entry nameiIGKC_MOUSE
AccessioniPrimary (citable) accession number: P01837
Secondary accession number(s): A0A075B5P2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: February 28, 2018
Last modified: May 23, 2018
This is version 155 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

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