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P01837

- IGKC_MOUSE

UniProt

P01837 - IGKC_MOUSE

Protein

Ig kappa chain C region

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. antigen binding Source: UniProtKB-KW

    Enzyme and pathway databases

    ReactomeiREACT_188194. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ig kappa chain C region
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    Organism-specific databases

    MGIiMGI:96495. Igk-C.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: Reactome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 106›106Ig kappa chain C regionPRO_0000153597Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi26 ↔ 861 PublicationPROSITE-ProRule annotation
    Disulfide bondi106 – 106Interchain (with a heavy chain)1 PublicationPROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    MaxQBiP01837.
    PaxDbiP01837.
    PRIDEiP01837.

    PTM databases

    PhosphoSiteiP01837.

    Expressioni

    Gene expression databases

    BgeeiP01837.
    GenevestigatoriP01837.

    Interactioni

    Protein-protein interaction databases

    IntActiP01837. 1 interaction.
    MINTiMINT-147676.

    Structurei

    Secondary structure

    1
    106
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi6 – 105
    Helixi14 – 185
    Beta strandi21 – 3414
    Beta strandi37 – 426
    Beta strandi45 – 473
    Beta strandi51 – 555
    Turni60 – 623
    Beta strandi65 – 7410
    Helixi75 – 784
    Beta strandi83 – 897
    Beta strandi90 – 956
    Beta strandi97 – 1026
    Helixi103 – 1053

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    15C8X-ray2.50L1-104[»]
    1A0QX-ray2.30L1-105[»]
    1A3LX-ray1.95L1-104[»]
    1AHWX-ray3.00A/D1-106[»]
    1AI1X-ray2.80L1-103[»]
    1AIFX-ray2.90A/L1-106[»]
    1C12X-ray2.60A1-105[»]
    1CF8X-ray2.70L1-106[»]
    1CFNX-ray2.65A1-106[»]
    1CFQX-ray2.80A1-106[»]
    1CFSX-ray2.75A1-106[»]
    1CFTX-ray2.80A1-106[»]
    1CICX-ray2.50A1-106[»]
    1CK0X-ray2.50L1-103[»]
    1CT8X-ray2.20A/C1-106[»]
    1DQJX-ray2.00A1-106[»]
    1DQMX-ray2.10L1-106[»]
    1DQQX-ray1.80A/C1-106[»]
    1E4WX-ray1.95L1-106[»]
    1E4XX-ray1.90L/M1-106[»]
    1EHLX-ray2.40L1-105[»]
    1EMTX-ray2.25L1-106[»]
    1FAIX-ray2.70L1-106[»]
    1FBIX-ray3.00L/P1-106[»]
    1FDLX-ray2.50L1-106[»]
    1FE8X-ray2.03L/M/N1-103[»]
    1FGNX-ray2.50L1-106[»]
    1FJ1X-ray2.68A/C1-105[»]
    1FL3X-ray2.45B/L1-102[»]
    1FNSX-ray2.00L1-106[»]
    1FRGX-ray2.80L1-103[»]
    1FSKX-ray2.90B/E/H/K1-106[»]
    1GPOX-ray1.95L/M1-106[»]
    1HH6X-ray2.60A1-106[»]
    1HH9X-ray2.70A1-106[»]
    1HI6X-ray2.55A1-106[»]
    1I8MX-ray2.10A/L1-106[»]
    1IAIX-ray2.90M1-106[»]
    1IGYX-ray3.20A/C1-106[»]
    1JNLX-ray3.00L1-103[»]
    1JNNX-ray3.20L1-103[»]
    1JRHX-ray2.80L1-106[»]
    1K4CX-ray2.00B1-104[»]
    1K4DX-ray2.30B1-104[»]
    1KB5X-ray2.50L1-106[»]
    1KC5X-ray2.50L1-106[»]
    1KCRX-ray2.90L1-106[»]
    1KCSX-ray2.50L1-106[»]
    1KCUX-ray2.20L1-106[»]
    1KCVX-ray1.80L1-106[»]
    1KENX-ray3.50L/U1-104[»]
    1KNOX-ray3.20A/C/E1-106[»]
    1LO0X-ray2.00L/X1-106[»]
    1MF2X-ray2.60L/M1-103[»]
    1MH5X-ray2.10A/L1-106[»]
    1MLBX-ray2.10A1-106[»]
    1MLCX-ray2.50A/C1-106[»]
    1N5YX-ray3.10L1-103[»]
    1N6QX-ray3.00L1-103[»]
    1NBYX-ray1.80A1-106[»]
    1NBZX-ray1.85A1-106[»]
    1NDGX-ray1.90A1-106[»]
    1NDMX-ray2.10A1-106[»]
    1OAKX-ray2.20L1-104[»]
    1OB1X-ray2.90A/D1-106[»]
    1ORQX-ray3.20A1-106[»]
    1ORSX-ray1.90A1-106[»]
    1OSPX-ray1.95L1-106[»]
    1OTSX-ray2.51D/F1-103[»]
    1OTTX-ray3.00D/F1-103[»]
    1OTUX-ray3.30D/F1-103[»]
    1P2CX-ray2.00A/D1-104[»]
    1P7KX-ray1.75A/L1-106[»]
    1PSKX-ray2.80L1-106[»]
    1Q9OX-ray1.79A/C1-106[»]
    1Q9WX-ray1.75A/C1-106[»]
    1QGCelectron microscopy30.0041-106[»]
    1R0AX-ray2.80L1-103[»]
    1R24X-ray3.10A/C1-98[»]
    1R3IX-ray2.40L1-104[»]
    1R3JX-ray1.90A1-104[»]
    1R3KX-ray2.80A1-104[»]
    1R3LX-ray2.41A1-104[»]
    1RIHX-ray2.50L1-106[»]
    1RUQX-ray1.86L1-104[»]
    1RURX-ray1.50L1-104[»]
    1S5HX-ray2.20A1-104[»]
    1SEQX-ray1.78L1-106[»]
    1T03X-ray3.10L1-103[»]
    1T4KX-ray2.50C1-104[»]
    1UB5X-ray2.00B/L1-101[»]
    1UB6X-ray2.12B/L1-101[»]
    1UWXX-ray2.20K/L1-105[»]
    1XF2X-ray2.30A/L1-106[»]
    1XF3X-ray2.30A/L1-106[»]
    1XF4X-ray2.50A/L1-106[»]
    1XGPX-ray2.10A1-106[»]
    1XGQX-ray2.10A1-106[»]
    1XGUX-ray2.10A1-106[»]
    25C8X-ray2.00L1-103[»]
    2A6DX-ray2.90L1-106[»]
    2A6KX-ray3.00A/L1-106[»]
    2ADFX-ray1.90L1-102[»]
    2ADJX-ray2.90A1-106[»]
    2AJSX-ray1.70L1-103[»]
    2AJUX-ray1.50L1-103[»]
    2AJVX-ray1.50L1-103[»]
    2AJXX-ray1.85L1-103[»]
    2AJYX-ray2.10L1-103[»]
    2AJZX-ray2.30A/L1-103[»]
    2AK1X-ray1.85L1-103[»]
    2BOBX-ray2.76B1-104[»]
    2BOCX-ray3.01B1-104[»]
    2CK0X-ray2.20L1-103[»]
    2F19X-ray2.80L1-106[»]
    2FR4X-ray1.95A1-106[»]
    2G5BX-ray2.30C/E/G1-104[»]
    2H8PX-ray2.25B1-104[»]
    2HG5X-ray2.75B1-104[»]
    2HRPX-ray2.20L/M1-106[»]
    2MPAX-ray2.60L8-12[»]
    2NR6X-ray2.81C/E1-103[»]
    2Q76X-ray2.00A/C1-104[»]
    2R1WX-ray1.70A1-106[»]
    2R1YX-ray1.60A1-106[»]
    2R23X-ray1.65A1-106[»]
    2R2BX-ray1.60A1-106[»]
    2UYLX-ray2.50A/M/V/X1-106[»]
    2V17X-ray1.65L1-106[»]
    2V7HX-ray2.80A/L1-106[»]
    2VC2X-ray3.10L1-106[»]
    2VDKX-ray2.80L1-106[»]
    2VDLX-ray2.75L1-106[»]
    2VDMX-ray2.90L1-106[»]
    2VDNX-ray2.90L1-106[»]
    2VDOX-ray2.51L1-106[»]
    2VDPX-ray2.80L1-106[»]
    2VDQX-ray2.59L1-106[»]
    2VDRX-ray2.40L1-106[»]
    2VL5X-ray2.10B/D1-106[»]
    2VQ1X-ray2.50A/E1-104[»]
    2VWEX-ray3.40C/J1-106[»]
    2W60X-ray1.50B1-104[»]
    2W65X-ray2.21B/D1-104[»]
    2W9DX-ray1.57L1-105[»]
    2W9EX-ray2.90L1-105[»]
    2Z91X-ray2.60B/D1-106[»]
    2Z92X-ray2.30B1-106[»]
    2Z93X-ray2.40B/D1-106[»]
    2ZJSX-ray3.20L1-106[»]
    35C8X-ray2.00L1-103[»]
    3BAEX-ray1.59L1-105[»]
    3BGFX-ray3.00C/L1-104[»]
    3BKCX-ray1.90L1-106[»]
    3BKJX-ray1.59L1-106[»]
    3BKMX-ray1.60L1-106[»]
    3BPCX-ray1.85A1-106[»]
    3BQUX-ray3.00C1-103[»]
    3BSZX-ray3.38L/M1-103[»]
    3BT2X-ray2.50L1-106[»]
    3BZ4X-ray1.80A/C/E/G1-106[»]
    3C5SX-ray2.00A/C1-106[»]
    3C6SX-ray1.80A/C/E/G1-106[»]
    3CFBX-ray1.60A/L1-106[»]
    3CFCX-ray1.70L1-106[»]
    3CFDX-ray2.50A/L1-106[»]
    3CFEX-ray2.99A/L1-106[»]
    3CK0X-ray3.00L1-103[»]
    3CLEX-ray2.50L1-106[»]
    3CLFX-ray2.00L1-106[»]
    3CMOX-ray2.30L/X1-103[»]
    3CVHX-ray2.90L/R1-102[»]
    3CVIX-ray1.80L1-102[»]
    3D9AX-ray1.20L1-105[»]
    3EJZX-ray2.90D/F1-103[»]
    3EOTX-ray1.90L1-106[»]
    3F7VX-ray3.20B1-104[»]
    3F7YX-ray3.40B1-104[»]
    3FB6X-ray3.00B1-104[»]
    3HFMX-ray3.00L1-106[»]
    4KK5X-ray3.17D/F1-103[»]
    4KK8X-ray2.86D/F1-103[»]
    6FABX-ray1.90L1-106[»]
    ProteinModelPortaliP01837.
    SMRiP01837. Positions 1-105.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP01837.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini5 – 10298Ig-likeAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Immunoglobulin C region, Immunoglobulin domain

    Phylogenomic databases

    eggNOGiNOG116969.
    HOVERGENiHBG039526.
    InParanoidiP01837.
    OMAiKSFNRNE.
    PhylomeDBiP01837.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    [Graphical view]
    SMARTiSM00407. IGc1. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P01837-1 [UniParc]FASTAAdd to Basket

    « Hide

    ADAAPTVSIF PPSSEQLTSG GASVVCFLNN FYPKDINVKW KIDGSERQNG    50
    VLNSWTDQDS KDSTYSMSST LTLTKDEYER HNSYTCEATH KTSTSPIVKS 100
    FNRNEC 106
    Length:106
    Mass (Da):11,778
    Last modified:July 21, 1986 - v1
    Checksum:i4B51FF5EF49BAEB5
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    V00807 Genomic DNA. Translation: CAA24189.1.
    PIRiB90262. K1MS.
    UniGeneiMm.333124.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    V00807 Genomic DNA. Translation: CAA24189.1 .
    PIRi B90262. K1MS.
    UniGenei Mm.333124.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    15C8 X-ray 2.50 L 1-104 [» ]
    1A0Q X-ray 2.30 L 1-105 [» ]
    1A3L X-ray 1.95 L 1-104 [» ]
    1AHW X-ray 3.00 A/D 1-106 [» ]
    1AI1 X-ray 2.80 L 1-103 [» ]
    1AIF X-ray 2.90 A/L 1-106 [» ]
    1C12 X-ray 2.60 A 1-105 [» ]
    1CF8 X-ray 2.70 L 1-106 [» ]
    1CFN X-ray 2.65 A 1-106 [» ]
    1CFQ X-ray 2.80 A 1-106 [» ]
    1CFS X-ray 2.75 A 1-106 [» ]
    1CFT X-ray 2.80 A 1-106 [» ]
    1CIC X-ray 2.50 A 1-106 [» ]
    1CK0 X-ray 2.50 L 1-103 [» ]
    1CT8 X-ray 2.20 A/C 1-106 [» ]
    1DQJ X-ray 2.00 A 1-106 [» ]
    1DQM X-ray 2.10 L 1-106 [» ]
    1DQQ X-ray 1.80 A/C 1-106 [» ]
    1E4W X-ray 1.95 L 1-106 [» ]
    1E4X X-ray 1.90 L/M 1-106 [» ]
    1EHL X-ray 2.40 L 1-105 [» ]
    1EMT X-ray 2.25 L 1-106 [» ]
    1FAI X-ray 2.70 L 1-106 [» ]
    1FBI X-ray 3.00 L/P 1-106 [» ]
    1FDL X-ray 2.50 L 1-106 [» ]
    1FE8 X-ray 2.03 L/M/N 1-103 [» ]
    1FGN X-ray 2.50 L 1-106 [» ]
    1FJ1 X-ray 2.68 A/C 1-105 [» ]
    1FL3 X-ray 2.45 B/L 1-102 [» ]
    1FNS X-ray 2.00 L 1-106 [» ]
    1FRG X-ray 2.80 L 1-103 [» ]
    1FSK X-ray 2.90 B/E/H/K 1-106 [» ]
    1GPO X-ray 1.95 L/M 1-106 [» ]
    1HH6 X-ray 2.60 A 1-106 [» ]
    1HH9 X-ray 2.70 A 1-106 [» ]
    1HI6 X-ray 2.55 A 1-106 [» ]
    1I8M X-ray 2.10 A/L 1-106 [» ]
    1IAI X-ray 2.90 M 1-106 [» ]
    1IGY X-ray 3.20 A/C 1-106 [» ]
    1JNL X-ray 3.00 L 1-103 [» ]
    1JNN X-ray 3.20 L 1-103 [» ]
    1JRH X-ray 2.80 L 1-106 [» ]
    1K4C X-ray 2.00 B 1-104 [» ]
    1K4D X-ray 2.30 B 1-104 [» ]
    1KB5 X-ray 2.50 L 1-106 [» ]
    1KC5 X-ray 2.50 L 1-106 [» ]
    1KCR X-ray 2.90 L 1-106 [» ]
    1KCS X-ray 2.50 L 1-106 [» ]
    1KCU X-ray 2.20 L 1-106 [» ]
    1KCV X-ray 1.80 L 1-106 [» ]
    1KEN X-ray 3.50 L/U 1-104 [» ]
    1KNO X-ray 3.20 A/C/E 1-106 [» ]
    1LO0 X-ray 2.00 L/X 1-106 [» ]
    1MF2 X-ray 2.60 L/M 1-103 [» ]
    1MH5 X-ray 2.10 A/L 1-106 [» ]
    1MLB X-ray 2.10 A 1-106 [» ]
    1MLC X-ray 2.50 A/C 1-106 [» ]
    1N5Y X-ray 3.10 L 1-103 [» ]
    1N6Q X-ray 3.00 L 1-103 [» ]
    1NBY X-ray 1.80 A 1-106 [» ]
    1NBZ X-ray 1.85 A 1-106 [» ]
    1NDG X-ray 1.90 A 1-106 [» ]
    1NDM X-ray 2.10 A 1-106 [» ]
    1OAK X-ray 2.20 L 1-104 [» ]
    1OB1 X-ray 2.90 A/D 1-106 [» ]
    1ORQ X-ray 3.20 A 1-106 [» ]
    1ORS X-ray 1.90 A 1-106 [» ]
    1OSP X-ray 1.95 L 1-106 [» ]
    1OTS X-ray 2.51 D/F 1-103 [» ]
    1OTT X-ray 3.00 D/F 1-103 [» ]
    1OTU X-ray 3.30 D/F 1-103 [» ]
    1P2C X-ray 2.00 A/D 1-104 [» ]
    1P7K X-ray 1.75 A/L 1-106 [» ]
    1PSK X-ray 2.80 L 1-106 [» ]
    1Q9O X-ray 1.79 A/C 1-106 [» ]
    1Q9W X-ray 1.75 A/C 1-106 [» ]
    1QGC electron microscopy 30.00 4 1-106 [» ]
    1R0A X-ray 2.80 L 1-103 [» ]
    1R24 X-ray 3.10 A/C 1-98 [» ]
    1R3I X-ray 2.40 L 1-104 [» ]
    1R3J X-ray 1.90 A 1-104 [» ]
    1R3K X-ray 2.80 A 1-104 [» ]
    1R3L X-ray 2.41 A 1-104 [» ]
    1RIH X-ray 2.50 L 1-106 [» ]
    1RUQ X-ray 1.86 L 1-104 [» ]
    1RUR X-ray 1.50 L 1-104 [» ]
    1S5H X-ray 2.20 A 1-104 [» ]
    1SEQ X-ray 1.78 L 1-106 [» ]
    1T03 X-ray 3.10 L 1-103 [» ]
    1T4K X-ray 2.50 C 1-104 [» ]
    1UB5 X-ray 2.00 B/L 1-101 [» ]
    1UB6 X-ray 2.12 B/L 1-101 [» ]
    1UWX X-ray 2.20 K/L 1-105 [» ]
    1XF2 X-ray 2.30 A/L 1-106 [» ]
    1XF3 X-ray 2.30 A/L 1-106 [» ]
    1XF4 X-ray 2.50 A/L 1-106 [» ]
    1XGP X-ray 2.10 A 1-106 [» ]
    1XGQ X-ray 2.10 A 1-106 [» ]
    1XGU X-ray 2.10 A 1-106 [» ]
    25C8 X-ray 2.00 L 1-103 [» ]
    2A6D X-ray 2.90 L 1-106 [» ]
    2A6K X-ray 3.00 A/L 1-106 [» ]
    2ADF X-ray 1.90 L 1-102 [» ]
    2ADJ X-ray 2.90 A 1-106 [» ]
    2AJS X-ray 1.70 L 1-103 [» ]
    2AJU X-ray 1.50 L 1-103 [» ]
    2AJV X-ray 1.50 L 1-103 [» ]
    2AJX X-ray 1.85 L 1-103 [» ]
    2AJY X-ray 2.10 L 1-103 [» ]
    2AJZ X-ray 2.30 A/L 1-103 [» ]
    2AK1 X-ray 1.85 L 1-103 [» ]
    2BOB X-ray 2.76 B 1-104 [» ]
    2BOC X-ray 3.01 B 1-104 [» ]
    2CK0 X-ray 2.20 L 1-103 [» ]
    2F19 X-ray 2.80 L 1-106 [» ]
    2FR4 X-ray 1.95 A 1-106 [» ]
    2G5B X-ray 2.30 C/E/G 1-104 [» ]
    2H8P X-ray 2.25 B 1-104 [» ]
    2HG5 X-ray 2.75 B 1-104 [» ]
    2HRP X-ray 2.20 L/M 1-106 [» ]
    2MPA X-ray 2.60 L 8-12 [» ]
    2NR6 X-ray 2.81 C/E 1-103 [» ]
    2Q76 X-ray 2.00 A/C 1-104 [» ]
    2R1W X-ray 1.70 A 1-106 [» ]
    2R1Y X-ray 1.60 A 1-106 [» ]
    2R23 X-ray 1.65 A 1-106 [» ]
    2R2B X-ray 1.60 A 1-106 [» ]
    2UYL X-ray 2.50 A/M/V/X 1-106 [» ]
    2V17 X-ray 1.65 L 1-106 [» ]
    2V7H X-ray 2.80 A/L 1-106 [» ]
    2VC2 X-ray 3.10 L 1-106 [» ]
    2VDK X-ray 2.80 L 1-106 [» ]
    2VDL X-ray 2.75 L 1-106 [» ]
    2VDM X-ray 2.90 L 1-106 [» ]
    2VDN X-ray 2.90 L 1-106 [» ]
    2VDO X-ray 2.51 L 1-106 [» ]
    2VDP X-ray 2.80 L 1-106 [» ]
    2VDQ X-ray 2.59 L 1-106 [» ]
    2VDR X-ray 2.40 L 1-106 [» ]
    2VL5 X-ray 2.10 B/D 1-106 [» ]
    2VQ1 X-ray 2.50 A/E 1-104 [» ]
    2VWE X-ray 3.40 C/J 1-106 [» ]
    2W60 X-ray 1.50 B 1-104 [» ]
    2W65 X-ray 2.21 B/D 1-104 [» ]
    2W9D X-ray 1.57 L 1-105 [» ]
    2W9E X-ray 2.90 L 1-105 [» ]
    2Z91 X-ray 2.60 B/D 1-106 [» ]
    2Z92 X-ray 2.30 B 1-106 [» ]
    2Z93 X-ray 2.40 B/D 1-106 [» ]
    2ZJS X-ray 3.20 L 1-106 [» ]
    35C8 X-ray 2.00 L 1-103 [» ]
    3BAE X-ray 1.59 L 1-105 [» ]
    3BGF X-ray 3.00 C/L 1-104 [» ]
    3BKC X-ray 1.90 L 1-106 [» ]
    3BKJ X-ray 1.59 L 1-106 [» ]
    3BKM X-ray 1.60 L 1-106 [» ]
    3BPC X-ray 1.85 A 1-106 [» ]
    3BQU X-ray 3.00 C 1-103 [» ]
    3BSZ X-ray 3.38 L/M 1-103 [» ]
    3BT2 X-ray 2.50 L 1-106 [» ]
    3BZ4 X-ray 1.80 A/C/E/G 1-106 [» ]
    3C5S X-ray 2.00 A/C 1-106 [» ]
    3C6S X-ray 1.80 A/C/E/G 1-106 [» ]
    3CFB X-ray 1.60 A/L 1-106 [» ]
    3CFC X-ray 1.70 L 1-106 [» ]
    3CFD X-ray 2.50 A/L 1-106 [» ]
    3CFE X-ray 2.99 A/L 1-106 [» ]
    3CK0 X-ray 3.00 L 1-103 [» ]
    3CLE X-ray 2.50 L 1-106 [» ]
    3CLF X-ray 2.00 L 1-106 [» ]
    3CMO X-ray 2.30 L/X 1-103 [» ]
    3CVH X-ray 2.90 L/R 1-102 [» ]
    3CVI X-ray 1.80 L 1-102 [» ]
    3D9A X-ray 1.20 L 1-105 [» ]
    3EJZ X-ray 2.90 D/F 1-103 [» ]
    3EOT X-ray 1.90 L 1-106 [» ]
    3F7V X-ray 3.20 B 1-104 [» ]
    3F7Y X-ray 3.40 B 1-104 [» ]
    3FB6 X-ray 3.00 B 1-104 [» ]
    3HFM X-ray 3.00 L 1-106 [» ]
    4KK5 X-ray 3.17 D/F 1-103 [» ]
    4KK8 X-ray 2.86 D/F 1-103 [» ]
    6FAB X-ray 1.90 L 1-106 [» ]
    ProteinModelPortali P01837.
    SMRi P01837. Positions 1-105.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P01837. 1 interaction.
    MINTi MINT-147676.

    Protein family/group databases

    IMGTi Search...

    PTM databases

    PhosphoSitei P01837.

    Proteomic databases

    MaxQBi P01837.
    PaxDbi P01837.
    PRIDEi P01837.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:96495. Igk-C.

    Phylogenomic databases

    eggNOGi NOG116969.
    HOVERGENi HBG039526.
    InParanoidi P01837.
    OMAi KSFNRNE.
    PhylomeDBi P01837.

    Enzyme and pathway databases

    Reactomei REACT_188194. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.

    Miscellaneous databases

    EvolutionaryTracei P01837.
    PROi P01837.

    Gene expression databases

    Bgeei P01837.
    Genevestigatori P01837.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    [Graphical view ]
    SMARTi SM00407. IGc1. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete amino acid sequence of a mouse kappa light chain."
      Svasti J., Milstein C.
      Biochem. J. 128:427-444(1972) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE (MOPC 21).
    2. "The disulphide bridges of a mouse immunoglobulin G1 protein."
      Svasti J., Milstein C.
      Biochem. J. 126:837-850(1972) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISULFIDE BONDS (MOPC 21).
    3. "Complete sequence of constant and 3' noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing."
      Hamlyn P.H., Brownlee G.G., Cheng C.-C., Gait M.J., Milstein C.
      Cell 15:1067-1075(1978) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SEQUENCE REVISION TO 53-59.
    4. "Complete sequence of an immunoglobulin mRNA using specific priming and the dideoxynucleotide method of RNA sequencing."
      Hamlyn P.H., Gait M.J., Milstein C.
      Nucleic Acids Res. 9:4485-4494(1981) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    5. "The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes."
      Max E.E., Maizel J.V. Jr., Leder P.
      J. Biol. Chem. 256:5116-5120(1981) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    6. "DNA sequence of the constant gene region of the mouse immunoglobulin kappa chain."
      Altenburger W., Neumaier P.S., Steinmetz M., Zachau H.G.
      Nucleic Acids Res. 9:971-981(1981) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    7. "Expression in non-lymphoid cells of mouse recombinant immunoglobulin directed against the tumour marker human placental alkaline phosphatase."
      de Waele P., Feys V., van de Voorde A., Molemans F., Fiers W.
      Eur. J. Biochem. 176:287-295(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiIGKC_MOUSE
    AccessioniPrimary (citable) accession number: P01837
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 127 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3