Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P01837

- IGKC_MOUSE

UniProt

P01837 - IGKC_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ig kappa chain C region

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antigen binding Source: UniProtKB-KW
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_188194. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.
REACT_188202. FCERI mediated Ca+2 mobilization.
REACT_188204. Fc epsilon receptor (FCERI) signaling.
REACT_188530. FCERI mediated MAPK activation.
REACT_196487. FCGR activation.
REACT_196575. Scavenging of heme from plasma.
REACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_202834. Initial triggering of complement.
REACT_202937. Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
REACT_205561. FCERI mediated NF-kB activation.
REACT_209334. Classical antibody-mediated complement activation.
REACT_210240. Role of phospholipids in phagocytosis.
REACT_213364. Role of LAT2/NTAL/LAB on calcium mobilization.

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain C region
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:96495. Igk-C.

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: Reactome
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 106›106Ig kappa chain C regionPRO_0000153597Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi26 ↔ 861 PublicationPROSITE-ProRule annotation
Disulfide bondi106 – 106Interchain (with a heavy chain)1 PublicationPROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP01837.
PaxDbiP01837.
PRIDEiP01837.

PTM databases

PhosphoSiteiP01837.

Expressioni

Gene expression databases

BgeeiP01837.
GenevestigatoriP01837.

Interactioni

Protein-protein interaction databases

IntActiP01837. 1 interaction.
MINTiMINT-147676.

Structurei

Secondary structure

1
106
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi6 – 105Combined sources
Helixi14 – 185Combined sources
Beta strandi21 – 3414Combined sources
Beta strandi37 – 426Combined sources
Beta strandi45 – 473Combined sources
Beta strandi51 – 555Combined sources
Turni60 – 623Combined sources
Beta strandi65 – 7410Combined sources
Helixi75 – 784Combined sources
Beta strandi83 – 897Combined sources
Beta strandi90 – 956Combined sources
Beta strandi97 – 1026Combined sources
Helixi103 – 1053Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
15C8X-ray2.50L1-104[»]
1A0QX-ray2.30L1-105[»]
1A3LX-ray1.95L1-104[»]
1AHWX-ray3.00A/D1-106[»]
1AI1X-ray2.80L1-103[»]
1AIFX-ray2.90A/L1-106[»]
1C12X-ray2.60A1-105[»]
1CF8X-ray2.70L1-106[»]
1CFNX-ray2.65A1-106[»]
1CFQX-ray2.80A1-106[»]
1CFSX-ray2.75A1-106[»]
1CFTX-ray2.80A1-106[»]
1CICX-ray2.50A1-106[»]
1CK0X-ray2.50L1-103[»]
1CT8X-ray2.20A/C1-106[»]
1DQJX-ray2.00A1-106[»]
1DQMX-ray2.10L1-106[»]
1DQQX-ray1.80A/C1-106[»]
1E4WX-ray1.95L1-106[»]
1E4XX-ray1.90L/M1-106[»]
1EHLX-ray2.40L1-105[»]
1EMTX-ray2.25L1-106[»]
1FAIX-ray2.70L1-106[»]
1FBIX-ray3.00L/P1-106[»]
1FDLX-ray2.50L1-106[»]
1FE8X-ray2.03L/M/N1-103[»]
1FGNX-ray2.50L1-106[»]
1FJ1X-ray2.68A/C1-105[»]
1FL3X-ray2.45B/L1-102[»]
1FNSX-ray2.00L1-106[»]
1FRGX-ray2.80L1-103[»]
1FSKX-ray2.90B/E/H/K1-106[»]
1GPOX-ray1.95L/M1-106[»]
1HH6X-ray2.60A1-106[»]
1HH9X-ray2.70A1-106[»]
1HI6X-ray2.55A1-106[»]
1I8MX-ray2.10A/L1-106[»]
1IAIX-ray2.90M1-106[»]
1IGYX-ray3.20A/C1-106[»]
1JNLX-ray3.00L1-103[»]
1JNNX-ray3.20L1-103[»]
1JRHX-ray2.80L1-106[»]
1K4CX-ray2.00B1-104[»]
1K4DX-ray2.30B1-104[»]
1KB5X-ray2.50L1-106[»]
1KC5X-ray2.50L1-106[»]
1KCRX-ray2.90L1-106[»]
1KCSX-ray2.50L1-106[»]
1KCUX-ray2.20L1-106[»]
1KCVX-ray1.80L1-106[»]
1KENX-ray3.50L/U1-104[»]
1KNOX-ray3.20A/C/E1-106[»]
1LO0X-ray2.00L/X1-106[»]
1MF2X-ray2.60L/M1-103[»]
1MH5X-ray2.10A/L1-106[»]
1MLBX-ray2.10A1-106[»]
1MLCX-ray2.50A/C1-106[»]
1N5YX-ray3.10L1-103[»]
1N6QX-ray3.00L1-103[»]
1NBYX-ray1.80A1-106[»]
1NBZX-ray1.85A1-106[»]
1NDGX-ray1.90A1-106[»]
1NDMX-ray2.10A1-106[»]
1OAKX-ray2.20L1-104[»]
1OB1X-ray2.90A/D1-106[»]
1ORQX-ray3.20A1-106[»]
1ORSX-ray1.90A1-106[»]
1OSPX-ray1.95L1-106[»]
1OTSX-ray2.51D/F1-103[»]
1OTTX-ray3.00D/F1-103[»]
1OTUX-ray3.30D/F1-103[»]
1P2CX-ray2.00A/D1-104[»]
1P7KX-ray1.75A/L1-106[»]
1PSKX-ray2.80L1-106[»]
1Q9OX-ray1.79A/C1-106[»]
1Q9WX-ray1.75A/C1-106[»]
1QGCelectron microscopy30.0041-106[»]
1R0AX-ray2.80L1-103[»]
1R24X-ray3.10A/C1-98[»]
1R3IX-ray2.40L1-104[»]
1R3JX-ray1.90A1-104[»]
1R3KX-ray2.80A1-104[»]
1R3LX-ray2.41A1-104[»]
1RIHX-ray2.50L1-106[»]
1RUQX-ray1.86L1-104[»]
1RURX-ray1.50L1-104[»]
1S5HX-ray2.20A1-104[»]
1SEQX-ray1.78L1-106[»]
1T03X-ray3.10L1-103[»]
1T4KX-ray2.50C1-104[»]
1UB5X-ray2.00B/L1-101[»]
1UB6X-ray2.12B/L1-101[»]
1UWXX-ray2.20K/L1-105[»]
1XF2X-ray2.30A/L1-106[»]
1XF3X-ray2.30A/L1-106[»]
1XF4X-ray2.50A/L1-106[»]
1XGPX-ray2.10A1-106[»]
1XGQX-ray2.10A1-106[»]
1XGUX-ray2.10A1-106[»]
25C8X-ray2.00L1-103[»]
2A6DX-ray2.90L1-106[»]
2A6KX-ray3.00A/L1-106[»]
2ADFX-ray1.90L1-102[»]
2ADJX-ray2.90A1-106[»]
2AJSX-ray1.70L1-103[»]
2AJUX-ray1.50L1-103[»]
2AJVX-ray1.50L1-103[»]
2AJXX-ray1.85L1-103[»]
2AJYX-ray2.10L1-103[»]
2AJZX-ray2.30A/L1-103[»]
2AK1X-ray1.85L1-103[»]
2BOBX-ray2.76B1-104[»]
2BOCX-ray3.01B1-104[»]
2CK0X-ray2.20L1-103[»]
2F19X-ray2.80L1-106[»]
2FR4X-ray1.95A1-106[»]
2G5BX-ray2.30C/E/G1-104[»]
2H8PX-ray2.25B1-104[»]
2HG5X-ray2.75B1-104[»]
2HRPX-ray2.20L/M1-106[»]
2MPAX-ray2.60L8-12[»]
2NR6X-ray2.81C/E1-103[»]
2Q76X-ray2.00A/C1-104[»]
2R1WX-ray1.70A1-106[»]
2R1YX-ray1.60A1-106[»]
2R23X-ray1.65A1-106[»]
2R2BX-ray1.60A1-106[»]
2UYLX-ray2.50A/M/V/X1-106[»]
2V17X-ray1.65L1-106[»]
2V7HX-ray2.80A/L1-106[»]
2VC2X-ray3.10L1-106[»]
2VDKX-ray2.80L1-106[»]
2VDLX-ray2.75L1-106[»]
2VDMX-ray2.90L1-106[»]
2VDNX-ray2.90L1-106[»]
2VDOX-ray2.51L1-106[»]
2VDPX-ray2.80L1-106[»]
2VDQX-ray2.59L1-106[»]
2VDRX-ray2.40L1-106[»]
2VL5X-ray2.10B/D1-106[»]
2VQ1X-ray2.50A/E1-104[»]
2VWEX-ray3.40C/J1-106[»]
2W60X-ray1.50B1-104[»]
2W65X-ray2.21B/D1-104[»]
2W9DX-ray1.57L1-105[»]
2W9EX-ray2.90L1-105[»]
2Z91X-ray2.60B/D1-106[»]
2Z92X-ray2.30B1-106[»]
2Z93X-ray2.40B/D1-106[»]
2ZJSX-ray3.20L1-106[»]
35C8X-ray2.00L1-103[»]
3BAEX-ray1.59L1-105[»]
3BGFX-ray3.00C/L1-104[»]
3BKCX-ray1.90L1-106[»]
3BKJX-ray1.59L1-106[»]
3BKMX-ray1.60L1-106[»]
3BPCX-ray1.85A1-106[»]
3BQUX-ray3.00C1-103[»]
3BSZX-ray3.38L/M1-103[»]
3BT2X-ray2.50L1-106[»]
3BZ4X-ray1.80A/C/E/G1-106[»]
3C5SX-ray2.00A/C1-106[»]
3C6SX-ray1.80A/C/E/G1-106[»]
3CFBX-ray1.60A/L1-106[»]
3CFCX-ray1.70L1-106[»]
3CFDX-ray2.50A/L1-106[»]
3CFEX-ray2.99A/L1-106[»]
3CK0X-ray3.00L1-103[»]
3CLEX-ray2.50L1-106[»]
3CLFX-ray2.00L1-106[»]
3CMOX-ray2.30L/X1-103[»]
3CVHX-ray2.90L/R1-102[»]
3CVIX-ray1.80L1-102[»]
3D9AX-ray1.20L1-105[»]
3EJZX-ray2.90D/F1-103[»]
3EOTX-ray1.90L1-106[»]
3F7VX-ray3.20B1-104[»]
3F7YX-ray3.40B1-104[»]
3FB6X-ray3.00B1-104[»]
3HFMX-ray3.00L1-106[»]
4KK5X-ray3.17D/F1-103[»]
4KK8X-ray2.86D/F1-103[»]
6FABX-ray1.90L1-106[»]
ProteinModelPortaliP01837.
SMRiP01837. Positions 1-105.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01837.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 10298Ig-likeAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin C region, Immunoglobulin domain

Phylogenomic databases

eggNOGiNOG116969.
HOVERGENiHBG039526.
InParanoidiP01837.
OMAiKSFNRNE.
PhylomeDBiP01837.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01837-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
ADAAPTVSIF PPSSEQLTSG GASVVCFLNN FYPKDINVKW KIDGSERQNG
60 70 80 90 100
VLNSWTDQDS KDSTYSMSST LTLTKDEYER HNSYTCEATH KTSTSPIVKS

FNRNEC
Length:106
Mass (Da):11,778
Last modified:July 21, 1986 - v1
Checksum:i4B51FF5EF49BAEB5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00807 Genomic DNA. Translation: CAA24189.1.
PIRiB90262. K1MS.
UniGeneiMm.333124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00807 Genomic DNA. Translation: CAA24189.1 .
PIRi B90262. K1MS.
UniGenei Mm.333124.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
15C8 X-ray 2.50 L 1-104 [» ]
1A0Q X-ray 2.30 L 1-105 [» ]
1A3L X-ray 1.95 L 1-104 [» ]
1AHW X-ray 3.00 A/D 1-106 [» ]
1AI1 X-ray 2.80 L 1-103 [» ]
1AIF X-ray 2.90 A/L 1-106 [» ]
1C12 X-ray 2.60 A 1-105 [» ]
1CF8 X-ray 2.70 L 1-106 [» ]
1CFN X-ray 2.65 A 1-106 [» ]
1CFQ X-ray 2.80 A 1-106 [» ]
1CFS X-ray 2.75 A 1-106 [» ]
1CFT X-ray 2.80 A 1-106 [» ]
1CIC X-ray 2.50 A 1-106 [» ]
1CK0 X-ray 2.50 L 1-103 [» ]
1CT8 X-ray 2.20 A/C 1-106 [» ]
1DQJ X-ray 2.00 A 1-106 [» ]
1DQM X-ray 2.10 L 1-106 [» ]
1DQQ X-ray 1.80 A/C 1-106 [» ]
1E4W X-ray 1.95 L 1-106 [» ]
1E4X X-ray 1.90 L/M 1-106 [» ]
1EHL X-ray 2.40 L 1-105 [» ]
1EMT X-ray 2.25 L 1-106 [» ]
1FAI X-ray 2.70 L 1-106 [» ]
1FBI X-ray 3.00 L/P 1-106 [» ]
1FDL X-ray 2.50 L 1-106 [» ]
1FE8 X-ray 2.03 L/M/N 1-103 [» ]
1FGN X-ray 2.50 L 1-106 [» ]
1FJ1 X-ray 2.68 A/C 1-105 [» ]
1FL3 X-ray 2.45 B/L 1-102 [» ]
1FNS X-ray 2.00 L 1-106 [» ]
1FRG X-ray 2.80 L 1-103 [» ]
1FSK X-ray 2.90 B/E/H/K 1-106 [» ]
1GPO X-ray 1.95 L/M 1-106 [» ]
1HH6 X-ray 2.60 A 1-106 [» ]
1HH9 X-ray 2.70 A 1-106 [» ]
1HI6 X-ray 2.55 A 1-106 [» ]
1I8M X-ray 2.10 A/L 1-106 [» ]
1IAI X-ray 2.90 M 1-106 [» ]
1IGY X-ray 3.20 A/C 1-106 [» ]
1JNL X-ray 3.00 L 1-103 [» ]
1JNN X-ray 3.20 L 1-103 [» ]
1JRH X-ray 2.80 L 1-106 [» ]
1K4C X-ray 2.00 B 1-104 [» ]
1K4D X-ray 2.30 B 1-104 [» ]
1KB5 X-ray 2.50 L 1-106 [» ]
1KC5 X-ray 2.50 L 1-106 [» ]
1KCR X-ray 2.90 L 1-106 [» ]
1KCS X-ray 2.50 L 1-106 [» ]
1KCU X-ray 2.20 L 1-106 [» ]
1KCV X-ray 1.80 L 1-106 [» ]
1KEN X-ray 3.50 L/U 1-104 [» ]
1KNO X-ray 3.20 A/C/E 1-106 [» ]
1LO0 X-ray 2.00 L/X 1-106 [» ]
1MF2 X-ray 2.60 L/M 1-103 [» ]
1MH5 X-ray 2.10 A/L 1-106 [» ]
1MLB X-ray 2.10 A 1-106 [» ]
1MLC X-ray 2.50 A/C 1-106 [» ]
1N5Y X-ray 3.10 L 1-103 [» ]
1N6Q X-ray 3.00 L 1-103 [» ]
1NBY X-ray 1.80 A 1-106 [» ]
1NBZ X-ray 1.85 A 1-106 [» ]
1NDG X-ray 1.90 A 1-106 [» ]
1NDM X-ray 2.10 A 1-106 [» ]
1OAK X-ray 2.20 L 1-104 [» ]
1OB1 X-ray 2.90 A/D 1-106 [» ]
1ORQ X-ray 3.20 A 1-106 [» ]
1ORS X-ray 1.90 A 1-106 [» ]
1OSP X-ray 1.95 L 1-106 [» ]
1OTS X-ray 2.51 D/F 1-103 [» ]
1OTT X-ray 3.00 D/F 1-103 [» ]
1OTU X-ray 3.30 D/F 1-103 [» ]
1P2C X-ray 2.00 A/D 1-104 [» ]
1P7K X-ray 1.75 A/L 1-106 [» ]
1PSK X-ray 2.80 L 1-106 [» ]
1Q9O X-ray 1.79 A/C 1-106 [» ]
1Q9W X-ray 1.75 A/C 1-106 [» ]
1QGC electron microscopy 30.00 4 1-106 [» ]
1R0A X-ray 2.80 L 1-103 [» ]
1R24 X-ray 3.10 A/C 1-98 [» ]
1R3I X-ray 2.40 L 1-104 [» ]
1R3J X-ray 1.90 A 1-104 [» ]
1R3K X-ray 2.80 A 1-104 [» ]
1R3L X-ray 2.41 A 1-104 [» ]
1RIH X-ray 2.50 L 1-106 [» ]
1RUQ X-ray 1.86 L 1-104 [» ]
1RUR X-ray 1.50 L 1-104 [» ]
1S5H X-ray 2.20 A 1-104 [» ]
1SEQ X-ray 1.78 L 1-106 [» ]
1T03 X-ray 3.10 L 1-103 [» ]
1T4K X-ray 2.50 C 1-104 [» ]
1UB5 X-ray 2.00 B/L 1-101 [» ]
1UB6 X-ray 2.12 B/L 1-101 [» ]
1UWX X-ray 2.20 K/L 1-105 [» ]
1XF2 X-ray 2.30 A/L 1-106 [» ]
1XF3 X-ray 2.30 A/L 1-106 [» ]
1XF4 X-ray 2.50 A/L 1-106 [» ]
1XGP X-ray 2.10 A 1-106 [» ]
1XGQ X-ray 2.10 A 1-106 [» ]
1XGU X-ray 2.10 A 1-106 [» ]
25C8 X-ray 2.00 L 1-103 [» ]
2A6D X-ray 2.90 L 1-106 [» ]
2A6K X-ray 3.00 A/L 1-106 [» ]
2ADF X-ray 1.90 L 1-102 [» ]
2ADJ X-ray 2.90 A 1-106 [» ]
2AJS X-ray 1.70 L 1-103 [» ]
2AJU X-ray 1.50 L 1-103 [» ]
2AJV X-ray 1.50 L 1-103 [» ]
2AJX X-ray 1.85 L 1-103 [» ]
2AJY X-ray 2.10 L 1-103 [» ]
2AJZ X-ray 2.30 A/L 1-103 [» ]
2AK1 X-ray 1.85 L 1-103 [» ]
2BOB X-ray 2.76 B 1-104 [» ]
2BOC X-ray 3.01 B 1-104 [» ]
2CK0 X-ray 2.20 L 1-103 [» ]
2F19 X-ray 2.80 L 1-106 [» ]
2FR4 X-ray 1.95 A 1-106 [» ]
2G5B X-ray 2.30 C/E/G 1-104 [» ]
2H8P X-ray 2.25 B 1-104 [» ]
2HG5 X-ray 2.75 B 1-104 [» ]
2HRP X-ray 2.20 L/M 1-106 [» ]
2MPA X-ray 2.60 L 8-12 [» ]
2NR6 X-ray 2.81 C/E 1-103 [» ]
2Q76 X-ray 2.00 A/C 1-104 [» ]
2R1W X-ray 1.70 A 1-106 [» ]
2R1Y X-ray 1.60 A 1-106 [» ]
2R23 X-ray 1.65 A 1-106 [» ]
2R2B X-ray 1.60 A 1-106 [» ]
2UYL X-ray 2.50 A/M/V/X 1-106 [» ]
2V17 X-ray 1.65 L 1-106 [» ]
2V7H X-ray 2.80 A/L 1-106 [» ]
2VC2 X-ray 3.10 L 1-106 [» ]
2VDK X-ray 2.80 L 1-106 [» ]
2VDL X-ray 2.75 L 1-106 [» ]
2VDM X-ray 2.90 L 1-106 [» ]
2VDN X-ray 2.90 L 1-106 [» ]
2VDO X-ray 2.51 L 1-106 [» ]
2VDP X-ray 2.80 L 1-106 [» ]
2VDQ X-ray 2.59 L 1-106 [» ]
2VDR X-ray 2.40 L 1-106 [» ]
2VL5 X-ray 2.10 B/D 1-106 [» ]
2VQ1 X-ray 2.50 A/E 1-104 [» ]
2VWE X-ray 3.40 C/J 1-106 [» ]
2W60 X-ray 1.50 B 1-104 [» ]
2W65 X-ray 2.21 B/D 1-104 [» ]
2W9D X-ray 1.57 L 1-105 [» ]
2W9E X-ray 2.90 L 1-105 [» ]
2Z91 X-ray 2.60 B/D 1-106 [» ]
2Z92 X-ray 2.30 B 1-106 [» ]
2Z93 X-ray 2.40 B/D 1-106 [» ]
2ZJS X-ray 3.20 L 1-106 [» ]
35C8 X-ray 2.00 L 1-103 [» ]
3BAE X-ray 1.59 L 1-105 [» ]
3BGF X-ray 3.00 C/L 1-104 [» ]
3BKC X-ray 1.90 L 1-106 [» ]
3BKJ X-ray 1.59 L 1-106 [» ]
3BKM X-ray 1.60 L 1-106 [» ]
3BPC X-ray 1.85 A 1-106 [» ]
3BQU X-ray 3.00 C 1-103 [» ]
3BSZ X-ray 3.38 L/M 1-103 [» ]
3BT2 X-ray 2.50 L 1-106 [» ]
3BZ4 X-ray 1.80 A/C/E/G 1-106 [» ]
3C5S X-ray 2.00 A/C 1-106 [» ]
3C6S X-ray 1.80 A/C/E/G 1-106 [» ]
3CFB X-ray 1.60 A/L 1-106 [» ]
3CFC X-ray 1.70 L 1-106 [» ]
3CFD X-ray 2.50 A/L 1-106 [» ]
3CFE X-ray 2.99 A/L 1-106 [» ]
3CK0 X-ray 3.00 L 1-103 [» ]
3CLE X-ray 2.50 L 1-106 [» ]
3CLF X-ray 2.00 L 1-106 [» ]
3CMO X-ray 2.30 L/X 1-103 [» ]
3CVH X-ray 2.90 L/R 1-102 [» ]
3CVI X-ray 1.80 L 1-102 [» ]
3D9A X-ray 1.20 L 1-105 [» ]
3EJZ X-ray 2.90 D/F 1-103 [» ]
3EOT X-ray 1.90 L 1-106 [» ]
3F7V X-ray 3.20 B 1-104 [» ]
3F7Y X-ray 3.40 B 1-104 [» ]
3FB6 X-ray 3.00 B 1-104 [» ]
3HFM X-ray 3.00 L 1-106 [» ]
4KK5 X-ray 3.17 D/F 1-103 [» ]
4KK8 X-ray 2.86 D/F 1-103 [» ]
6FAB X-ray 1.90 L 1-106 [» ]
ProteinModelPortali P01837.
SMRi P01837. Positions 1-105.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P01837. 1 interaction.
MINTi MINT-147676.

Protein family/group databases

IMGTi Search...

PTM databases

PhosphoSitei P01837.

Proteomic databases

MaxQBi P01837.
PaxDbi P01837.
PRIDEi P01837.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:96495. Igk-C.

Phylogenomic databases

eggNOGi NOG116969.
HOVERGENi HBG039526.
InParanoidi P01837.
OMAi KSFNRNE.
PhylomeDBi P01837.

Enzyme and pathway databases

Reactomei REACT_188194. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.
REACT_188202. FCERI mediated Ca+2 mobilization.
REACT_188204. Fc epsilon receptor (FCERI) signaling.
REACT_188530. FCERI mediated MAPK activation.
REACT_196487. FCGR activation.
REACT_196575. Scavenging of heme from plasma.
REACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_202834. Initial triggering of complement.
REACT_202937. Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
REACT_205561. FCERI mediated NF-kB activation.
REACT_209334. Classical antibody-mediated complement activation.
REACT_210240. Role of phospholipids in phagocytosis.
REACT_213364. Role of LAT2/NTAL/LAB on calcium mobilization.

Miscellaneous databases

EvolutionaryTracei P01837.
PROi P01837.

Gene expression databases

Bgeei P01837.
Genevestigatori P01837.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
[Graphical view ]
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete amino acid sequence of a mouse kappa light chain."
    Svasti J., Milstein C.
    Biochem. J. 128:427-444(1972) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE (MOPC 21).
  2. "The disulphide bridges of a mouse immunoglobulin G1 protein."
    Svasti J., Milstein C.
    Biochem. J. 126:837-850(1972) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISULFIDE BONDS (MOPC 21).
  3. "Complete sequence of constant and 3' noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing."
    Hamlyn P.H., Brownlee G.G., Cheng C.-C., Gait M.J., Milstein C.
    Cell 15:1067-1075(1978) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SEQUENCE REVISION TO 53-59.
  4. "Complete sequence of an immunoglobulin mRNA using specific priming and the dideoxynucleotide method of RNA sequencing."
    Hamlyn P.H., Gait M.J., Milstein C.
    Nucleic Acids Res. 9:4485-4494(1981) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  5. "The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes."
    Max E.E., Maizel J.V. Jr., Leder P.
    J. Biol. Chem. 256:5116-5120(1981) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  6. "DNA sequence of the constant gene region of the mouse immunoglobulin kappa chain."
    Altenburger W., Neumaier P.S., Steinmetz M., Zachau H.G.
    Nucleic Acids Res. 9:971-981(1981) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  7. "Expression in non-lymphoid cells of mouse recombinant immunoglobulin directed against the tumour marker human placental alkaline phosphatase."
    de Waele P., Feys V., van de Voorde A., Molemans F., Fiers W.
    Eur. J. Biochem. 176:287-295(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiIGKC_MOUSE
AccessioniPrimary (citable) accession number: P01837
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 26, 2014
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3