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Protein

Ig heavy chain V region MOPC 315

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

This alpha chain was isolated from a myeloma protein that has anti-dinitrophenyl activity.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region MOPC 315
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 182 PublicationsAdd BLAST18
ChainiPRO_000001523219 – 137Ig heavy chain V region MOPC 315Add BLAST119

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi40 ↔ 114PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP01822.

Structurei

3D structure databases

ProteinModelPortaliP01822.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 48Framework-1Add BLAST30
Regioni49 – 54Complementarity-determining-16
Regioni55 – 68Framework-2Add BLAST14
Regioni69 – 84Complementarity-determining-2Add BLAST16
Regioni85 – 116Framework-3Add BLAST32
Regioni117 – 126Complementarity-determining-310
Regioni127 – 137Framework-4Add BLAST11

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

HOGENOMiHOG000154831.
HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
PfamiView protein in Pfam
PF07686. V-set. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01822-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLSLLYLL TAIPGIMSDV QLQESGPGLV KPSQSLSLTC SVTGYSITSG
60 70 80 90 100
YFWNWIRQFP GNKLEWLGFI KYDGSNGYNP SLKNRVSITR DTSENQFFLK
110 120 130
LNSVTTEDTA TYYCAGDNDH LYYFDYWGQG TTLTVSS
Length:137
Mass (Da):15,399
Last modified:August 1, 1992 - v2
Checksum:iFB3828304C2B81DC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti15G → GG in CAA30727 (PubMed:2497341).Curated1
Sequence conflicti15G → H AA sequence (PubMed:414225).Curated1
Sequence conflicti77 – 78GY → YG AA sequence (PubMed:4524622).Curated2
Sequence conflicti102N → D AA sequence (PubMed:4524622).Curated1
Sequence conflicti123Missing AA sequence (PubMed:4524622).Curated1
Non-terminal residuei1371

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M27638 Genomic DNA. Translation: AAA61337.1.
X07880 Genomic DNA. Translation: CAA30727.1.
PIRiPL0102. AVMS35.
UniGeneiMm.303767.

Similar proteinsi

Entry informationi

Entry nameiHVM46_MOUSE
AccessioniPrimary (citable) accession number: P01822
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: August 1, 1992
Last modified: October 25, 2017
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome