ID   HVM44_MOUSE             Reviewed;         115 AA.
AC   P01820;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   27-MAR-2024, entry version 138.
DE   RecName: Full=Ig heavy chain V region PJ14;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6774258; DOI=10.1038/286676a0;
RA   Sakano H., Maki R., Kurosawa Y., Roeder W., Tonegawa S.;
RT   "Two types of somatic recombination are necessary for the generation of
RT   complete immunoglobulin heavy-chain genes.";
RL   Nature 286:676-683(1980).
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DR   EMBL; V00767; CAA24148.1; -; Genomic_DNA.
DR   PIR; A02095; HVMS14.
DR   PDB; 1A2Y; X-ray; 1.50 A; B=20-115.
DR   PDB; 1A7N; X-ray; 2.01 A; H=20-115.
DR   PDB; 1A7O; X-ray; 2.00 A; H=20-115.
DR   PDB; 1A7P; X-ray; 2.01 A; H=20-115.
DR   PDB; 1A7Q; X-ray; 2.00 A; H=20-115.
DR   PDB; 1A7R; X-ray; 2.01 A; H=20-115.
DR   PDB; 1DL7; X-ray; 2.35 A; H=20-115.
DR   PDB; 1DVF; X-ray; 1.90 A; B=20-115.
DR   PDB; 1G7H; X-ray; 1.85 A; B=20-115.
DR   PDB; 1G7I; X-ray; 1.80 A; B=20-115.
DR   PDB; 1G7J; X-ray; 1.75 A; B=20-115.
DR   PDB; 1G7L; X-ray; 2.00 A; B=20-115.
DR   PDB; 1G7M; X-ray; 1.90 A; B=20-115.
DR   PDB; 1KIR; X-ray; 2.00 A; B=20-115.
DR   PDB; 1P4B; X-ray; 2.35 A; H=21-114.
DR   PDB; 1P4I; X-ray; 2.80 A; H=21-114.
DR   PDB; 1VFA; X-ray; 1.80 A; B=20-115.
DR   PDB; 1VFB; X-ray; 1.80 A; B=20-115.
DR   PDB; 43C9; X-ray; 2.20 A; B/D/F/H=20-114.
DR   PDB; 43CA; X-ray; 2.30 A; B/D/F/H=20-114.
DR   PDBsum; 1A2Y; -.
DR   PDBsum; 1A7N; -.
DR   PDBsum; 1A7O; -.
DR   PDBsum; 1A7P; -.
DR   PDBsum; 1A7Q; -.
DR   PDBsum; 1A7R; -.
DR   PDBsum; 1DL7; -.
DR   PDBsum; 1DVF; -.
DR   PDBsum; 1G7H; -.
DR   PDBsum; 1G7I; -.
DR   PDBsum; 1G7J; -.
DR   PDBsum; 1G7L; -.
DR   PDBsum; 1G7M; -.
DR   PDBsum; 1KIR; -.
DR   PDBsum; 1P4B; -.
DR   PDBsum; 1P4I; -.
DR   PDBsum; 1VFA; -.
DR   PDBsum; 1VFB; -.
DR   PDBsum; 43C9; -.
DR   PDBsum; 43CA; -.
DR   AlphaFoldDB; P01820; -.
DR   SMR; P01820; -.
DR   IntAct; P01820; 1.
DR   MINT; P01820; -.
DR   MaxQB; P01820; -.
DR   InParanoid; P01820; -.
DR   EvolutionaryTrace; P01820; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01820; Protein.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR23266:SF269; IG HEAVY CHAIN V REGION MC101-RELATED; 1.
DR   PANTHER; PTHR23266; IMMUNOGLOBULIN HEAVY CHAIN; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Immunity; Immunoglobulin;
KW   Reference proteome; Signal.
FT   SIGNAL          1..19
FT   CHAIN           20..115
FT                   /note="Ig heavy chain V region PJ14"
FT                   /id="PRO_0000015230"
FT   DOMAIN          20..>115
FT                   /note="Ig-like"
FT   NON_TER         115
FT   STRAND          22..26
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   STRAND          29..31
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   STRAND          37..46
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   STRAND          50..58
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   TURN            60..62
FT                   /evidence="ECO:0007829|PDB:43C9"
FT   STRAND          65..70
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   STRAND          72..74
FT                   /evidence="ECO:0007829|PDB:43C9"
FT   STRAND          76..78
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   TURN            80..82
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   HELIX           83..85
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   STRAND          86..91
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   HELIX           92..94
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   STRAND          96..101
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   HELIX           106..108
FT                   /evidence="ECO:0007829|PDB:1A2Y"
FT   STRAND          110..115
FT                   /evidence="ECO:0007829|PDB:1A2Y"
SQ   SEQUENCE   115 AA;  12447 MW;  7569DD4A4843D500 CRC64;
     MAVLALLFCL VTFPSCILSQ VQLKESGPGL VAPSQSLSIT CTVSGFSLTG YGVNWVRQPP
     GKGLEWLGMI WGDGSTDYNS ALKSRLSISK DNSKSQVFLK MNSLQTDDTA RYYCA
//