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P01820

- HVM44_MOUSE

UniProt

P01820 - HVM44_MOUSE

Protein

Ig heavy chain V region PJ14

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. antigen binding Source: UniProtKB-KW

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ig heavy chain V region PJ14
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Add
    BLAST
    Chaini20 – 11596Ig heavy chain V region PJ14PRO_0000015230Add
    BLAST

    Proteomic databases

    PaxDbiP01820.

    Expressioni

    Gene expression databases

    GenevestigatoriP01820.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    P017231EBI-1027999,EBI-1037949

    Protein-protein interaction databases

    IntActiP01820. 1 interaction.
    MINTiMINT-135771.

    Structurei

    Secondary structure

    1
    115
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi22 – 265
    Beta strandi29 – 313
    Beta strandi37 – 4610
    Beta strandi50 – 589
    Turni60 – 623
    Beta strandi65 – 706
    Beta strandi72 – 743
    Beta strandi76 – 783
    Turni80 – 823
    Helixi83 – 853
    Beta strandi86 – 916
    Helixi92 – 943
    Beta strandi96 – 1016
    Helixi106 – 1083
    Beta strandi110 – 1156

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1A2YX-ray1.50B20-115[»]
    1A7NX-ray2.01H20-115[»]
    1A7OX-ray2.00H20-115[»]
    1A7PX-ray2.01H20-115[»]
    1A7QX-ray2.00H20-115[»]
    1A7RX-ray2.01H20-115[»]
    1DL7X-ray2.35H20-115[»]
    1DVFX-ray1.90B20-115[»]
    1G7HX-ray1.85B20-115[»]
    1G7IX-ray1.80B20-115[»]
    1G7JX-ray1.75B20-115[»]
    1G7LX-ray2.00B20-115[»]
    1G7MX-ray1.90B20-115[»]
    1KIRX-ray2.00B20-115[»]
    1P4BX-ray2.35H21-114[»]
    1P4IX-ray2.80H21-114[»]
    1VFAX-ray1.80B20-115[»]
    1VFBX-ray1.80B20-115[»]
    43C9X-ray2.20B/D/F/H20-114[»]
    43CAX-ray2.30B/D/F/H20-114[»]
    ProteinModelPortaliP01820.
    SMRiP01820. Positions 20-115.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP01820.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini20 – ›115›96Ig-likeAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Immunoglobulin domain, Immunoglobulin V region, Signal

    Phylogenomic databases

    eggNOGiNOG28103.
    HOGENOMiHOG000154831.
    HOVERGENiHBG018013.
    InParanoidiP01820.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view]
    PfamiPF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00406. IGv. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P01820-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVLALLFCL VTFPSCILSQ VQLKESGPGL VAPSQSLSIT CTVSGFSLTG    50
    YGVNWVRQPP GKGLEWLGMI WGDGSTDYNS ALKSRLSISK DNSKSQVFLK 100
    MNSLQTDDTA RYYCA 115
    Length:115
    Mass (Da):12,447
    Last modified:July 21, 1986 - v1
    Checksum:i7569DD4A4843D500
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei115 – 1151

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    V00767 Genomic DNA. Translation: CAA24148.1.
    PIRiA02095. HVMS14.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    V00767 Genomic DNA. Translation: CAA24148.1 .
    PIRi A02095. HVMS14.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1A2Y X-ray 1.50 B 20-115 [» ]
    1A7N X-ray 2.01 H 20-115 [» ]
    1A7O X-ray 2.00 H 20-115 [» ]
    1A7P X-ray 2.01 H 20-115 [» ]
    1A7Q X-ray 2.00 H 20-115 [» ]
    1A7R X-ray 2.01 H 20-115 [» ]
    1DL7 X-ray 2.35 H 20-115 [» ]
    1DVF X-ray 1.90 B 20-115 [» ]
    1G7H X-ray 1.85 B 20-115 [» ]
    1G7I X-ray 1.80 B 20-115 [» ]
    1G7J X-ray 1.75 B 20-115 [» ]
    1G7L X-ray 2.00 B 20-115 [» ]
    1G7M X-ray 1.90 B 20-115 [» ]
    1KIR X-ray 2.00 B 20-115 [» ]
    1P4B X-ray 2.35 H 21-114 [» ]
    1P4I X-ray 2.80 H 21-114 [» ]
    1VFA X-ray 1.80 B 20-115 [» ]
    1VFB X-ray 1.80 B 20-115 [» ]
    43C9 X-ray 2.20 B/D/F/H 20-114 [» ]
    43CA X-ray 2.30 B/D/F/H 20-114 [» ]
    ProteinModelPortali P01820.
    SMRi P01820. Positions 20-115.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P01820. 1 interaction.
    MINTi MINT-135771.

    Protein family/group databases

    IMGTi Search...

    Proteomic databases

    PaxDbi P01820.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG28103.
    HOGENOMi HOG000154831.
    HOVERGENi HBG018013.
    InParanoidi P01820.

    Miscellaneous databases

    EvolutionaryTracei P01820.

    Gene expression databases

    Genevestigatori P01820.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view ]
    Pfami PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00406. IGv. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes."
      Sakano H., Maki R., Kurosawa Y., Roeder W., Tonegawa S.
      Nature 286:676-683(1980) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiHVM44_MOUSE
    AccessioniPrimary (citable) accession number: P01820
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3