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P01820

- HVM44_MOUSE

UniProt

P01820 - HVM44_MOUSE

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Protein

Ig heavy chain V region PJ14

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antigen binding Source: UniProtKB-KW
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region PJ14
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Add
BLAST
Chaini20 – 11596Ig heavy chain V region PJ14PRO_0000015230Add
BLAST

Proteomic databases

PaxDbiP01820.

Expressioni

Gene expression databases

GenevestigatoriP01820.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
P017231EBI-1027999,EBI-1037949

Protein-protein interaction databases

IntActiP01820. 1 interaction.
MINTiMINT-135771.

Structurei

Secondary structure

1
115
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi22 – 265
Beta strandi29 – 313
Beta strandi37 – 4610
Beta strandi50 – 589
Turni60 – 623
Beta strandi65 – 706
Beta strandi72 – 743
Beta strandi76 – 783
Turni80 – 823
Helixi83 – 853
Beta strandi86 – 916
Helixi92 – 943
Beta strandi96 – 1016
Helixi106 – 1083
Beta strandi110 – 1156

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1A2YX-ray1.50B20-115[»]
1A7NX-ray2.01H20-115[»]
1A7OX-ray2.00H20-115[»]
1A7PX-ray2.01H20-115[»]
1A7QX-ray2.00H20-115[»]
1A7RX-ray2.01H20-115[»]
1DL7X-ray2.35H20-115[»]
1DVFX-ray1.90B20-115[»]
1G7HX-ray1.85B20-115[»]
1G7IX-ray1.80B20-115[»]
1G7JX-ray1.75B20-115[»]
1G7LX-ray2.00B20-115[»]
1G7MX-ray1.90B20-115[»]
1KIRX-ray2.00B20-115[»]
1P4BX-ray2.35H21-114[»]
1P4IX-ray2.80H21-114[»]
1VFAX-ray1.80B20-115[»]
1VFBX-ray1.80B20-115[»]
43C9X-ray2.20B/D/F/H20-114[»]
43CAX-ray2.30B/D/F/H20-114[»]
ProteinModelPortaliP01820.
SMRiP01820. Positions 20-115.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01820.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – ›115›96Ig-likeAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

eggNOGiNOG28103.
HOGENOMiHOG000154831.
HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01820-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVLALLFCL VTFPSCILSQ VQLKESGPGL VAPSQSLSIT CTVSGFSLTG
60 70 80 90 100
YGVNWVRQPP GKGLEWLGMI WGDGSTDYNS ALKSRLSISK DNSKSQVFLK
110
MNSLQTDDTA RYYCA
Length:115
Mass (Da):12,447
Last modified:July 21, 1986 - v1
Checksum:i7569DD4A4843D500
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei115 – 1151

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
V00767 Genomic DNA. Translation: CAA24148.1.
PIRiA02095. HVMS14.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
V00767 Genomic DNA. Translation: CAA24148.1 .
PIRi A02095. HVMS14.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1A2Y X-ray 1.50 B 20-115 [» ]
1A7N X-ray 2.01 H 20-115 [» ]
1A7O X-ray 2.00 H 20-115 [» ]
1A7P X-ray 2.01 H 20-115 [» ]
1A7Q X-ray 2.00 H 20-115 [» ]
1A7R X-ray 2.01 H 20-115 [» ]
1DL7 X-ray 2.35 H 20-115 [» ]
1DVF X-ray 1.90 B 20-115 [» ]
1G7H X-ray 1.85 B 20-115 [» ]
1G7I X-ray 1.80 B 20-115 [» ]
1G7J X-ray 1.75 B 20-115 [» ]
1G7L X-ray 2.00 B 20-115 [» ]
1G7M X-ray 1.90 B 20-115 [» ]
1KIR X-ray 2.00 B 20-115 [» ]
1P4B X-ray 2.35 H 21-114 [» ]
1P4I X-ray 2.80 H 21-114 [» ]
1VFA X-ray 1.80 B 20-115 [» ]
1VFB X-ray 1.80 B 20-115 [» ]
43C9 X-ray 2.20 B/D/F/H 20-114 [» ]
43CA X-ray 2.30 B/D/F/H 20-114 [» ]
ProteinModelPortali P01820.
SMRi P01820. Positions 20-115.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P01820. 1 interaction.
MINTi MINT-135771.

Protein family/group databases

IMGTi Search...

Proteomic databases

PaxDbi P01820.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG28103.
HOGENOMi HOG000154831.
HOVERGENi HBG018013.

Miscellaneous databases

EvolutionaryTracei P01820.

Gene expression databases

Genevestigatori P01820.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view ]
Pfami PF07686. V-set. 1 hit.
[Graphical view ]
SMARTi SM00406. IGv. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes."
    Sakano H., Maki R., Kurosawa Y., Roeder W., Tonegawa S.
    Nature 286:676-683(1980) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiHVM44_MOUSE
AccessioniPrimary (citable) accession number: P01820
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 29, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3