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Protein

Ig heavy chain V region PJ14

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antigen binding Source: UniProtKB-KW
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region PJ14
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Add
BLAST
Chaini20 – 11596Ig heavy chain V region PJ14PRO_0000015230Add
BLAST

Proteomic databases

PaxDbiP01820.

Expressioni

Gene expression databases

GenevestigatoriP01820.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
P017231EBI-1027999,EBI-1037949

Protein-protein interaction databases

IntActiP01820. 1 interaction.
MINTiMINT-135771.

Structurei

Secondary structure

1
115
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi22 – 265Combined sources
Beta strandi29 – 313Combined sources
Beta strandi37 – 4610Combined sources
Beta strandi50 – 589Combined sources
Turni60 – 623Combined sources
Beta strandi65 – 706Combined sources
Beta strandi72 – 743Combined sources
Beta strandi76 – 783Combined sources
Turni80 – 823Combined sources
Helixi83 – 853Combined sources
Beta strandi86 – 916Combined sources
Helixi92 – 943Combined sources
Beta strandi96 – 1016Combined sources
Helixi106 – 1083Combined sources
Beta strandi110 – 1156Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1A2YX-ray1.50B20-115[»]
1A7NX-ray2.01H20-115[»]
1A7OX-ray2.00H20-115[»]
1A7PX-ray2.01H20-115[»]
1A7QX-ray2.00H20-115[»]
1A7RX-ray2.01H20-115[»]
1DL7X-ray2.35H20-115[»]
1DVFX-ray1.90B20-115[»]
1G7HX-ray1.85B20-115[»]
1G7IX-ray1.80B20-115[»]
1G7JX-ray1.75B20-115[»]
1G7LX-ray2.00B20-115[»]
1G7MX-ray1.90B20-115[»]
1KIRX-ray2.00B20-115[»]
1P4BX-ray2.35H21-114[»]
1P4IX-ray2.80H21-114[»]
1VFAX-ray1.80B20-115[»]
1VFBX-ray1.80B20-115[»]
43C9X-ray2.20B/D/F/H20-114[»]
43CAX-ray2.30B/D/F/H20-114[»]
ProteinModelPortaliP01820.
SMRiP01820. Positions 20-115.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01820.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – ›115›96Ig-likeAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

eggNOGiNOG28103.
HOGENOMiHOG000154831.
HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01820-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVLALLFCL VTFPSCILSQ VQLKESGPGL VAPSQSLSIT CTVSGFSLTG
60 70 80 90 100
YGVNWVRQPP GKGLEWLGMI WGDGSTDYNS ALKSRLSISK DNSKSQVFLK
110
MNSLQTDDTA RYYCA
Length:115
Mass (Da):12,447
Last modified:July 21, 1986 - v1
Checksum:i7569DD4A4843D500
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei115 – 1151

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00767 Genomic DNA. Translation: CAA24148.1.
PIRiA02095. HVMS14.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00767 Genomic DNA. Translation: CAA24148.1.
PIRiA02095. HVMS14.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1A2YX-ray1.50B20-115[»]
1A7NX-ray2.01H20-115[»]
1A7OX-ray2.00H20-115[»]
1A7PX-ray2.01H20-115[»]
1A7QX-ray2.00H20-115[»]
1A7RX-ray2.01H20-115[»]
1DL7X-ray2.35H20-115[»]
1DVFX-ray1.90B20-115[»]
1G7HX-ray1.85B20-115[»]
1G7IX-ray1.80B20-115[»]
1G7JX-ray1.75B20-115[»]
1G7LX-ray2.00B20-115[»]
1G7MX-ray1.90B20-115[»]
1KIRX-ray2.00B20-115[»]
1P4BX-ray2.35H21-114[»]
1P4IX-ray2.80H21-114[»]
1VFAX-ray1.80B20-115[»]
1VFBX-ray1.80B20-115[»]
43C9X-ray2.20B/D/F/H20-114[»]
43CAX-ray2.30B/D/F/H20-114[»]
ProteinModelPortaliP01820.
SMRiP01820. Positions 20-115.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP01820. 1 interaction.
MINTiMINT-135771.

Protein family/group databases

IMGTiSearch...

Proteomic databases

PaxDbiP01820.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiNOG28103.
HOGENOMiHOG000154831.
HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiP01820.

Gene expression databases

GenevestigatoriP01820.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes."
    Sakano H., Maki R., Kurosawa Y., Roeder W., Tonegawa S.
    Nature 286:676-683(1980) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiHVM44_MOUSE
AccessioniPrimary (citable) accession number: P01820
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: January 7, 2015
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.