P01811 (HVM41_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Ig heavy chain V region UPC10
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	117 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous	This chain was isolated from an Ig gamma-2a myeloma protein binding 2,6-levan.
Sequence similarities	Contains 1 Ig-like (immunoglobulin-like) domain.

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›117	›117	Ig heavy chain V region UPC10		PRO_0000059894
Regions
	Domain	1 – 116	116	Ig-like
Experimental info
	Non-terminal residue	117	1

Sequences

	Sequence		Length	Mass (Da)
	P01811 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: B20A1074F8E99E7F	FASTA	117	13,001
	10 20 30 40 50 60 EVKLLESGGG LVQPGGSLKL SCAASGFDFS GYWMSWVRQA PGKGLEWIGE INPDSSTINY 70 80 90 100 110 TPFLKDKFII SRDNAKNTLF LQMSKVRSED TALYFCARNW DVGFDYWGQV TTLTVSS

References

[1]	"Correlation between D region structure and antigen-binding specificity: evidences from the comparison of closely related immunoglobulin VH sequences." Auffray C., Sikorav J.-L., Ollo R., Rougeon F. Ann. Immunol. (Paris) 132D:77-88(1981) [PubMed: 6181731] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

M36631 mRNA. Translation: AAA38078.1.

IPI

IPI00457477.

PIR

G2MSU1. A02081.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1UZ6	X-ray	2.05	F/H/P/W	1-117	[»]
1UZ8	X-ray	1.80	B/H	1-117	[»]

ProteinModelPortal

P01811.

SMR

P01811. Positions 1-117.

ModBase

Search...

Protein-protein interaction databases

STRING

P01811.

Protein family/group databases

IMGT

Search...

Proteomic databases

PRIDE

P01811.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

HOVERGEN

HBG018013.

Gene expression databases

Genevestigator

P01811.

Family and domain databases

InterPro

IPR007110. Ig-like.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]

Gene3D

G3DSA:2.60.40.10. Ig-like_fold. 1 hit.

Pfam

PF07686. V-set. 1 hit.
[Graphical view]

SMART

SM00406. IGv. 1 hit.
[Graphical view]

PROSITE

PS50835. IG_LIKE. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

HVM41_MOUSE

Accession

Primary (citable) accession number: P01811

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	September 21, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program