Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ig heavy chain V region J539

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region J539
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›119›119Ig heavy chain V region J539PRO_0000059893Add
BLAST

Proteomic databases

PRIDEiP01810.

Interactioni

Protein-protein interaction databases

MINTiMINT-1560252.

Structurei

Secondary structure

1
119
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 75Combined sources
Beta strandi10 – 123Combined sources
Beta strandi18 – 2710Combined sources
Helixi29 – 313Combined sources
Beta strandi34 – 396Combined sources
Beta strandi45 – 517Combined sources
Beta strandi58 – 603Combined sources
Turni62 – 676Combined sources
Beta strandi68 – 725Combined sources
Beta strandi74 – 763Combined sources
Beta strandi78 – 836Combined sources
Helixi88 – 903Combined sources
Beta strandi92 – 1009Combined sources
Turni101 – 1033Combined sources
Beta strandi104 – 1085Combined sources
Beta strandi112 – 1165Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FBJX-ray1.95H1-119[»]
ProteinModelPortaliP01810.
SMRiP01810. Positions 1-119.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01810.

Family & Domainsi

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01810-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EVKLLESGGG LVQPGGSLKL SCAASGFDFS KYWMSWVRQA PGKGLEWIGE
60 70 80 90 100
IHPDSGTINY TPSLKDKFII SRDNAKNSLY LQMSKVRSED TALYYCARLH
110
YYGYNAYWGQ GTLVTVSAE
Length:119
Mass (Da):13,240
Last modified:July 21, 1986 - v1
Checksum:i577B4F1DB675C1F1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei119 – 1191

Sequence databases

PIRiA02080. AVMSJ5.

Cross-referencesi

Sequence databases

PIRiA02080. AVMSJ5.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FBJX-ray1.95H1-119[»]
ProteinModelPortaliP01810.
SMRiP01810. Positions 1-119.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1560252.

Proteomic databases

PRIDEiP01810.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiP01810.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structural evidence for independent joining region gene in immunoglobulin heavy chains from anti-galactan myeloma proteins and its potential role in generating diversity in complementarity-determining regions."
    Rao D.N., Rudikoff S., Krutzsch H., Potter M.
    Proc. Natl. Acad. Sci. U.S.A. 76:2890-2894(1979) [PubMed] [Europe PMC] [Abstract]
    Cited for: PRELIMINARY PROTEIN SEQUENCE.
  2. "The galactan-binding immunoglobulin Fab J539: an X-ray diffraction study at 2.6-A resolution."
    Suh S.W., Bhat T.N., Navia M.A., Cohen G.H., Rao D.N., Rudikoff S., Davies D.R.
    Proteins 1:74-80(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS).

Entry informationi

Entry nameiHVM40_MOUSE
AccessioniPrimary (citable) accession number: P01810
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: June 8, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This chain was isolated from a myeloma protein that binds galactan.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.