ID   HVM38_MOUSE             Reviewed;         119 AA.
AC   P01808;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   RecName: Full=Ig heavy chain V region T601;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=111245; DOI=10.1073/pnas.76.6.2890;
RA   Rao D.N., Rudikoff S., Krutzsch H., Potter M.;
RT   "Structural evidence for independent joining region gene in immunoglobulin
RT   heavy chains from anti-galactan myeloma proteins and its potential role in
RT   generating diversity in complementarity-determining regions.";
RL   Proc. Natl. Acad. Sci. U.S.A. 76:2890-2894(1979).
CC   -!- MISCELLANEOUS: This chain was isolated from an IgA myeloma protein that
CC       binds galactan.
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DR   PIR; A02078; AVMST6.
DR   PDB; 1OTS; X-ray; 2.51 A; C/E=1-118.
DR   PDB; 1OTT; X-ray; 3.00 A; C/E=1-118.
DR   PDB; 1OTU; X-ray; 3.30 A; C/E=1-118.
DR   PDB; 2EXW; X-ray; 3.20 A; C/E=1-118.
DR   PDB; 2EXY; X-ray; 3.10 A; C/E=1-118.
DR   PDB; 2EZ0; X-ray; 3.54 A; C/E=1-118.
DR   PDB; 2H2P; X-ray; 3.10 A; C/E=2-118.
DR   PDB; 2H2S; X-ray; 3.10 A; C/E=2-118.
DR   PDB; 2HLF; X-ray; 3.30 A; C/E=2-118.
DR   PDB; 2HT2; X-ray; 3.32 A; C/E=2-118.
DR   PDB; 2HT3; X-ray; 3.30 A; C/E=2-118.
DR   PDB; 2HT4; X-ray; 3.20 A; C/E=2-118.
DR   PDB; 2HTK; X-ray; 3.41 A; C/E=2-118.
DR   PDB; 2HTL; X-ray; 3.40 A; C/E=2-118.
DR   PDB; 3DET; X-ray; 2.80 A; C/E=2-118.
DR   PDB; 3EJY; X-ray; 3.20 A; C/E=2-118.
DR   PDB; 3EJZ; X-ray; 2.90 A; C/E=2-118.
DR   PDB; 3U0W; X-ray; 2.00 A; H=1-98.
DR   PDB; 4KKB; X-ray; 3.02 A; C/E=1-118.
DR   PDB; 4MQX; X-ray; 3.52 A; C/E=1-118.
DR   PDBsum; 1OTS; -.
DR   PDBsum; 1OTT; -.
DR   PDBsum; 1OTU; -.
DR   PDBsum; 2EXW; -.
DR   PDBsum; 2EXY; -.
DR   PDBsum; 2EZ0; -.
DR   PDBsum; 2H2P; -.
DR   PDBsum; 2H2S; -.
DR   PDBsum; 2HLF; -.
DR   PDBsum; 2HT2; -.
DR   PDBsum; 2HT3; -.
DR   PDBsum; 2HT4; -.
DR   PDBsum; 2HTK; -.
DR   PDBsum; 2HTL; -.
DR   PDBsum; 3DET; -.
DR   PDBsum; 3EJY; -.
DR   PDBsum; 3EJZ; -.
DR   PDBsum; 3U0W; -.
DR   PDBsum; 4KKB; -.
DR   PDBsum; 4MQX; -.
DR   AlphaFoldDB; P01808; -.
DR   SMR; P01808; -.
DR   MaxQB; P01808; -.
DR   MGI; MGI:96461; Igh-J.
DR   InParanoid; P01808; -.
DR   EvolutionaryTrace; P01808; -.
DR   PRO; PR:P01808; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01808; Protein.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IBA:GO_Central.
DR   CDD; cd04981; IgV_H; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR23266:SF219; IG HEAVY CHAIN V REGION 441-RELATED; 1.
DR   PANTHER; PTHR23266; IMMUNOGLOBULIN HEAVY CHAIN; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Direct protein sequencing; Immunity;
KW   Immunoglobulin; Reference proteome.
FT   CHAIN           1..>119
FT                   /note="Ig heavy chain V region T601"
FT                   /id="PRO_0000059891"
FT   DOMAIN          1..112
FT                   /note="Ig-like"
FT   NON_TER         119
FT   STRAND          3..7
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          10..12
FT                   /evidence="ECO:0007829|PDB:1OTS"
FT   STRAND          18..27
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   HELIX           29..31
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          34..39
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          45..51
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          58..60
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   HELIX           62..64
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   TURN            65..67
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          68..73
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   HELIX           74..76
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          78..83
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   HELIX           88..90
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          92..98
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   TURN            101..103
FT                   /evidence="ECO:0007829|PDB:3U0W"
FT   STRAND          105..108
FT                   /evidence="ECO:0007829|PDB:4KKB"
FT   STRAND          112..116
FT                   /evidence="ECO:0007829|PDB:3U0W"
SQ   SEQUENCE   119 AA;  13169 MW;  BC38CC84E6EA00E8 CRC64;
     EVKLLESGGG LVQPGGSLKL SCAASGFDFS RYWMSWVRQA PGKGLEWIGE INPDSSTINY
     TPSLKDKFII SRDNAKNTLY LQMSKVRSED TALYYCARLG YYGYFDVWGA GTTVTVSSE
//