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Protein

Ig heavy chain V region T601

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antigen binding Source: UniProtKB-KW
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region T601
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:96461. Igh-J.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›119›119Ig heavy chain V region T601PRO_0000059891Add
BLAST

Proteomic databases

PRIDEiP01808.

Expressioni

Gene expression databases

GenevestigatoriP01808.

Structurei

Secondary structure

1
119
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 75Combined sources
Beta strandi10 – 123Combined sources
Beta strandi18 – 2710Combined sources
Helixi29 – 313Combined sources
Beta strandi34 – 396Combined sources
Beta strandi45 – 517Combined sources
Beta strandi58 – 603Combined sources
Helixi62 – 643Combined sources
Turni65 – 673Combined sources
Beta strandi68 – 736Combined sources
Helixi74 – 763Combined sources
Beta strandi78 – 836Combined sources
Helixi88 – 903Combined sources
Beta strandi92 – 987Combined sources
Beta strandi104 – 1085Combined sources
Beta strandi112 – 1165Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1OTSX-ray2.51C/E1-118[»]
1OTTX-ray3.00C/E1-118[»]
1OTUX-ray3.30C/E1-118[»]
2EXWX-ray3.20C/E1-118[»]
2EXYX-ray3.10C/E1-118[»]
2EZ0X-ray3.54C/E1-118[»]
2H2PX-ray3.10C/E2-118[»]
2H2SX-ray3.10C/E2-118[»]
2HLFX-ray3.30C/E2-118[»]
2HT2X-ray3.32C/E2-118[»]
2HT3X-ray3.30C/E2-118[»]
2HT4X-ray3.20C/E2-118[»]
2HTKX-ray3.41C/E2-118[»]
2HTLX-ray3.40C/E2-118[»]
3DETX-ray2.80C/E2-118[»]
3EJYX-ray3.20C/E2-118[»]
3EJZX-ray2.90C/E2-118[»]
3U0WX-ray2.00H1-98[»]
4KKBX-ray3.02C/E1-118[»]
4MQXX-ray3.52C/E1-118[»]
ProteinModelPortaliP01808.
SMRiP01808. Positions 1-118.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01808.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 112112Ig-likeAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region

Phylogenomic databases

HOVERGENiHBG018013.
InParanoidiP01808.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01808-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
EVKLLESGGG LVQPGGSLKL SCAASGFDFS RYWMSWVRQA PGKGLEWIGE
60 70 80 90 100
INPDSSTINY TPSLKDKFII SRDNAKNTLY LQMSKVRSED TALYYCARLG
110
YYGYFDVWGA GTTVTVSSE
Length:119
Mass (Da):13,169
Last modified:July 21, 1986 - v1
Checksum:iBC38CC84E6EA00E8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei119 – 1191

Sequence databases

PIRiA02078. AVMST6.

Cross-referencesi

Sequence databases

PIRiA02078. AVMST6.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1OTSX-ray2.51C/E1-118[»]
1OTTX-ray3.00C/E1-118[»]
1OTUX-ray3.30C/E1-118[»]
2EXWX-ray3.20C/E1-118[»]
2EXYX-ray3.10C/E1-118[»]
2EZ0X-ray3.54C/E1-118[»]
2H2PX-ray3.10C/E2-118[»]
2H2SX-ray3.10C/E2-118[»]
2HLFX-ray3.30C/E2-118[»]
2HT2X-ray3.32C/E2-118[»]
2HT3X-ray3.30C/E2-118[»]
2HT4X-ray3.20C/E2-118[»]
2HTKX-ray3.41C/E2-118[»]
2HTLX-ray3.40C/E2-118[»]
3DETX-ray2.80C/E2-118[»]
3EJYX-ray3.20C/E2-118[»]
3EJZX-ray2.90C/E2-118[»]
3U0WX-ray2.00H1-98[»]
4KKBX-ray3.02C/E1-118[»]
4MQXX-ray3.52C/E1-118[»]
ProteinModelPortaliP01808.
SMRiP01808. Positions 1-118.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP01808.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:96461. Igh-J.

Phylogenomic databases

HOVERGENiHBG018013.
InParanoidiP01808.

Miscellaneous databases

EvolutionaryTraceiP01808.
NextBioi35563506.

Gene expression databases

GenevestigatoriP01808.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structural evidence for independent joining region gene in immunoglobulin heavy chains from anti-galactan myeloma proteins and its potential role in generating diversity in complementarity-determining regions."
    Rao D.N., Rudikoff S., Krutzsch H., Potter M.
    Proc. Natl. Acad. Sci. U.S.A. 76:2890-2894(1979) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.

Entry informationi

Entry nameiHVM38_MOUSE
AccessioniPrimary (citable) accession number: P01808
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: January 7, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This chain was isolated from an IgA myeloma protein that binds galactan.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.