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P01808

- HVM38_MOUSE

UniProt

P01808 - HVM38_MOUSE

Protein

Ig heavy chain V region T601

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. antigen binding Source: UniProtKB-KW

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ig heavy chain V region T601
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    Organism-specific databases

    MGIiMGI:96461. Igh-J.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›119›119Ig heavy chain V region T601PRO_0000059891Add
    BLAST

    Proteomic databases

    PRIDEiP01808.

    Expressioni

    Gene expression databases

    GenevestigatoriP01808.

    Structurei

    Secondary structure

    1
    119
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi3 – 75
    Beta strandi10 – 123
    Beta strandi18 – 2710
    Helixi29 – 313
    Beta strandi34 – 396
    Beta strandi45 – 517
    Beta strandi58 – 603
    Helixi62 – 643
    Turni65 – 673
    Beta strandi68 – 736
    Helixi74 – 763
    Beta strandi78 – 836
    Helixi88 – 903
    Beta strandi92 – 987
    Beta strandi104 – 1085
    Beta strandi112 – 1165

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1OTSX-ray2.51C/E1-118[»]
    1OTTX-ray3.00C/E1-118[»]
    1OTUX-ray3.30C/E1-118[»]
    2EXWX-ray3.20C/E1-118[»]
    2EXYX-ray3.10C/E1-118[»]
    2EZ0X-ray3.54C/E1-118[»]
    2H2PX-ray3.10C/E2-118[»]
    2H2SX-ray3.10C/E2-118[»]
    2HLFX-ray3.30C/E2-118[»]
    2HT2X-ray3.32C/E2-118[»]
    2HT3X-ray3.30C/E2-118[»]
    2HT4X-ray3.20C/E2-118[»]
    2HTKX-ray3.41C/E2-118[»]
    2HTLX-ray3.40C/E2-118[»]
    3DETX-ray2.80C/E2-118[»]
    3EJYX-ray3.20C/E2-118[»]
    3EJZX-ray2.90C/E2-118[»]
    3U0WX-ray2.00H1-98[»]
    4KKBX-ray3.02C/E1-118[»]
    4MQXX-ray3.52C/E1-118[»]
    ProteinModelPortaliP01808.
    SMRiP01808. Positions 1-118.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP01808.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 112112Ig-likeAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Immunoglobulin domain, Immunoglobulin V region

    Phylogenomic databases

    HOVERGENiHBG018013.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view]
    PfamiPF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00406. IGv. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P01808-1 [UniParc]FASTAAdd to Basket

    « Hide

    EVKLLESGGG LVQPGGSLKL SCAASGFDFS RYWMSWVRQA PGKGLEWIGE    50
    INPDSSTINY TPSLKDKFII SRDNAKNTLY LQMSKVRSED TALYYCARLG 100
    YYGYFDVWGA GTTVTVSSE 119
    Length:119
    Mass (Da):13,169
    Last modified:July 21, 1986 - v1
    Checksum:iBC38CC84E6EA00E8
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei119 – 1191

    Sequence databases

    PIRiA02078. AVMST6.

    Cross-referencesi

    Sequence databases

    PIRi A02078. AVMST6.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1OTS X-ray 2.51 C/E 1-118 [» ]
    1OTT X-ray 3.00 C/E 1-118 [» ]
    1OTU X-ray 3.30 C/E 1-118 [» ]
    2EXW X-ray 3.20 C/E 1-118 [» ]
    2EXY X-ray 3.10 C/E 1-118 [» ]
    2EZ0 X-ray 3.54 C/E 1-118 [» ]
    2H2P X-ray 3.10 C/E 2-118 [» ]
    2H2S X-ray 3.10 C/E 2-118 [» ]
    2HLF X-ray 3.30 C/E 2-118 [» ]
    2HT2 X-ray 3.32 C/E 2-118 [» ]
    2HT3 X-ray 3.30 C/E 2-118 [» ]
    2HT4 X-ray 3.20 C/E 2-118 [» ]
    2HTK X-ray 3.41 C/E 2-118 [» ]
    2HTL X-ray 3.40 C/E 2-118 [» ]
    3DET X-ray 2.80 C/E 2-118 [» ]
    3EJY X-ray 3.20 C/E 2-118 [» ]
    3EJZ X-ray 2.90 C/E 2-118 [» ]
    3U0W X-ray 2.00 H 1-98 [» ]
    4KKB X-ray 3.02 C/E 1-118 [» ]
    4MQX X-ray 3.52 C/E 1-118 [» ]
    ProteinModelPortali P01808.
    SMRi P01808. Positions 1-118.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P01808.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:96461. Igh-J.

    Phylogenomic databases

    HOVERGENi HBG018013.

    Miscellaneous databases

    EvolutionaryTracei P01808.
    NextBioi 35563506.

    Gene expression databases

    Genevestigatori P01808.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view ]
    Pfami PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00406. IGv. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural evidence for independent joining region gene in immunoglobulin heavy chains from anti-galactan myeloma proteins and its potential role in generating diversity in complementarity-determining regions."
      Rao D.N., Rudikoff S., Krutzsch H., Potter M.
      Proc. Natl. Acad. Sci. U.S.A. 76:2890-2894(1979) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.

    Entry informationi

    Entry nameiHVM38_MOUSE
    AccessioniPrimary (citable) accession number: P01808
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    This chain was isolated from an IgA myeloma protein that binds galactan.

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3