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Protein

Ig heavy chain V-III region J606

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V-III region J606
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›115›115Ig heavy chain V-III region J606PRO_0000059886Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi22 ↔ 98PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP01801.
PRIDEiP01801.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
P018372EBI-8556558,EBI-1035302

Protein-protein interaction databases

MINTiMINT-249808.

Structurei

Secondary structure

1
115
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 75Combined sources
Beta strandi10 – 123Combined sources
Beta strandi18 – 2710Combined sources
Helixi29 – 313Combined sources
Beta strandi33 – 408Combined sources
Turni41 – 433Combined sources
Beta strandi44 – 518Combined sources
Helixi54 – 563Combined sources
Beta strandi60 – 623Combined sources
Turni64 – 696Combined sources
Beta strandi70 – 756Combined sources
Turni76 – 794Combined sources
Beta strandi80 – 856Combined sources
Helixi90 – 923Combined sources
Beta strandi94 – 996Combined sources
Beta strandi103 – 1053Combined sources
Beta strandi109 – 1135Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1M71X-ray2.80B1-114[»]
1M7DX-ray2.30B1-114[»]
1M7IX-ray2.50B1-114[»]
1PZ5X-ray1.80B1-114[»]
1SM3X-ray1.95H2-114[»]
2DLFX-ray1.55H1-115[»]
5A2IX-ray1.88H6-99[»]
H102-115[»]
5A2JX-ray1.65H6-99[»]
H102-115[»]
5A2KX-ray1.70H6-99[»]
H102-115[»]
5A2LX-ray1.79H6-99[»]
H102-115[»]
ProteinModelPortaliP01801.
SMRiP01801. Positions 1-108.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01801.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 114114Ig-likeAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01801-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EVKLEESGGG LVQPGGSMKL SCVASGFTFS NYWMNWVRQS PEKGLEWVAE
60 70 80 90 100
IRLKSNNYAT HYAESVKGRF TISRDDSKSS VYLQMNNLRA EDTGIYYCTT
110
GFAYWGQGTL VTVSA
Length:115
Mass (Da):12,810
Last modified:July 21, 1986 - v1
Checksum:iB67AD6638A121A5F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei115 – 1151

Sequence databases

PIRiC92811. AVMS06.
UniGeneiMm.422809.
Mm.431322.

Cross-referencesi

Sequence databases

PIRiC92811. AVMS06.
UniGeneiMm.422809.
Mm.431322.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1M71X-ray2.80B1-114[»]
1M7DX-ray2.30B1-114[»]
1M7IX-ray2.50B1-114[»]
1PZ5X-ray1.80B1-114[»]
1SM3X-ray1.95H2-114[»]
2DLFX-ray1.55H1-115[»]
5A2IX-ray1.88H6-99[»]
H102-115[»]
5A2JX-ray1.65H6-99[»]
H102-115[»]
5A2KX-ray1.70H6-99[»]
H102-115[»]
5A2LX-ray1.79H6-99[»]
H102-115[»]
ProteinModelPortaliP01801.
SMRiP01801. Positions 1-108.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-249808.

Proteomic databases

MaxQBiP01801.
PRIDEiP01801.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiP01801.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The complete V domain amino acid sequences of two myeloma inulin-binding proteins."
    Johnson N., Slankard J., Paul L., Hood L.
    J. Immunol. 128:302-307(1982) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.

Entry informationi

Entry nameiHVM32_MOUSE
AccessioniPrimary (citable) accession number: P01801
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 11, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This chain was isolated from a myeloma protein that binds inulin.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.